Structures, Functions and Expressions of GnRH and GnRH Receptor in Peripheral Reproductive Organs and Their Regulation by Estradiol-17 beta

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dc.contributor.authorCiftci, H. B.
dc.date.accessioned2020-03-26T19:07:12Z
dc.date.available2020-03-26T19:07:12Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractStudies have shown that estradiol-17 beta (E-2) regulates gonadotropin-releasing hormone (GnRH) and GnRH receptor expression in hypothalamus and pituitary. Several studies have shown that GnRH and its receptor are also expressed in peripheral reproductive organs and little is known about their regulations. In this study, GnRH and GnRH receptor structures, functions, their peripheral expressions and regulations by E-2 were reviewed. Several in vivo and in vitro conducted studies indicate that E-2 decreases the expression of GnRH mRNA and regulates GnRH receptor expression in a time dependent manner. Nevertheless, the exact mechanism has not been clearly explained yet.en_US
dc.identifier.endpage786en_US
dc.identifier.issn2251-628Xen_US
dc.identifier.issn2251-631Xen_US
dc.identifier.issue4en_US
dc.identifier.pmid#YOKen_US
dc.identifier.startpage775en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32580
dc.identifier.volume5en_US
dc.identifier.wosWOS:000436766300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherISLAMIC AZAD UNIV, RASHTen_US
dc.relation.ispartofIRANIAN JOURNAL OF APPLIED ANIMAL SCIENCEen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectestradiolen_US
dc.subjectGnRHen_US
dc.subjectovaryen_US
dc.subjectoviducten_US
dc.subjectuterusen_US
dc.titleStructures, Functions and Expressions of GnRH and GnRH Receptor in Peripheral Reproductive Organs and Their Regulation by Estradiol-17 betaen_US
dc.typeReviewen_US

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