Oxygen Free Radicals in Children with Acute Rheumatic Fever

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dc.contributor.authorOran, B.
dc.contributor.authorAtabek, E.
dc.contributor.authorKaraaslan, S.
dc.contributor.authorReisli, Y.
dc.contributor.authorGültekin, F.
dc.contributor.authorErkul, Y.
dc.date.accessioned2020-03-26T16:37:18Z
dc.date.available2020-03-26T16:37:18Z
dc.date.issued2001
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractWe have investigated the relationship between oxygen free radicals and acute rheumatic fever with regard to diagnosis of the disease process. At the time of diagnosis, we measured the levels of reactive oxygen molecules in the plasma, this being a parameter for oxygen free radicals, and discovered the levels to be significantly higher when compared with those measured in a control group (P<0.05). The levels measured in the plasma, however, were not statistically different among patients with and without carditis. We found a progressive decrease in the levels measured in the plasma when patients with acute rheumatic fever were tested on the 15(th), 30(th) and 90(th) days subsequent to diagnosis. By the 90(th) day, levels measured in the plasma were still higher, but no longer significantly elevated, when compared with the control group. The present study is preliminary, but raises the possibility that measurement of oxygen free radicals in the plasma could be used as a laboratory test for active state of acute rheumatic fever. Further investigations will be needed, nonetheless, to determine the clinical application of this technique.en_US
dc.identifier.citationOran, B., Atabek, E., Karaaslan, S., Reisli, Y., Gültekin, F., Erkul, Y., (2001). Oxygen Free Radicals in Children with Acute Rheumatic Fever. Cardiology in the Young, 11(3), 285-288. Doi:10.1017/S1047951101000300
dc.identifier.doi10.1017/S1047951101000300en_US
dc.identifier.endpage288en_US
dc.identifier.issn1047-9511en_US
dc.identifier.issue3en_US
dc.identifier.pmid11388622en_US
dc.identifier.startpage285en_US
dc.identifier.urihttps://dx.doi.org/10.1017/S1047951101000300
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17586
dc.identifier.volume11en_US
dc.identifier.wosWOS:000168752600007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGREENWICH MEDICAL MEDIA LTDen_US
dc.relation.ispartofCardiology in the Youngen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectacute rheumatic feveren_US
dc.subjectoxygen free radicalsen_US
dc.subjectreactive oxygen moleculesen_US
dc.subjectgroup A beta hemolytic streptococcusen_US
dc.titleOxygen Free Radicals in Children with Acute Rheumatic Feveren_US
dc.typeArticleen_US

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