Effects of levamisole on pregnancy in ewes

Basit Öğe Kaydı
dc.contributor.authorPancarci, Sukru Metin
dc.contributor.authorGungor, Orsan
dc.contributor.authorGurbulak, Kutlay
dc.contributor.authorCenesiz, Metin
dc.contributor.authorKaya, Mehmet
dc.contributor.authorCenesiz, Sena
dc.contributor.authorGuzeloglu, Aydin
dc.date.accessioned2020-03-26T17:17:21Z
dc.date.available2020-03-26T17:17:21Z
dc.date.issued2007
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe effects of levamisole, as an anthelmintic or immunomodulator, on pregnancy were investigated in ewes. Immunomodulatory and anthelmintic doses of levamisole and physiologic saline were injected on days 0 (oestrus), 7, 14, and 21 in group I (immunomodulatory dose; n=7), group II (anthelmintic dose; n=6), and group III (control; n=6), respectively. The first service pregnancy rate, tended to be lower (P<0.06) in group I (28.6%) compared to that of groups II (83.3%) and III (83.3%). Plasma progesterone (P-4) concentration was significantly higher (P<0.05) in group II compared to that of group III on day 3, and there was a treatment x day interaction (P<0.05). No effect of levamisole treatments on plasma P-4 concentrations was detected once pregnancy was established. There was a numeric decline in plasma cholesterol concentrations in group II, compared to group I or III on day 3. In conclusion, levamisole as an immunomodulator is detrimental for the establishment of pregnancy, possibly by stimulating general and intrauterine immunity.en_US
dc.identifier.endpage256en_US
dc.identifier.issn0042-4870en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage253en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/21368
dc.identifier.volume51en_US
dc.identifier.wosWOS:000247794900013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNATL VETERINARY RESEARCH INSTen_US
dc.relation.ispartofBULLETIN OF THE VETERINARY INSTITUTE IN PULAWYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectewesen_US
dc.subjectlevamisoleen_US
dc.subjectimmuno-modulationen_US
dc.subjectpregnancyen_US
dc.titleEffects of levamisole on pregnancy in ewesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu