Fabrication of Calixarene Based Protein Scaffold by Electrospin Coating for Tissue Engineering

Küçük Resim Yok

Tarih

2018

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

AMER SCIENTIFIC PUBLISHERS

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

In this study, calixarene was synthesized by using different functional groups as p-tert-butyl-Calix[4] arene ester and amides. Calixarene nanofibers were produced by electrospin coating. Protein immobilization onto the calixarene nanofibers was carried out with human serum albumin (HSA). The maximum amount of binding on produced three different calixarene nanofibers (DE, 2-AMP and 3-AMP) was compared by using a fluorescence technique for protein analysis. Result showed that maximum binding amount was found to be as 177.85 mg cm(-2) for 3-AMP surface. The protein binding was also characterized by using SEM, TEM, AFM and FT-IR. From obtained results, calixarene-albumin nanofiber was also fabricated by spin coating using 3-AMP which has ability max binding of protein.

Açıklama

Anahtar Kelimeler

Nanofiber, Albumin, Protein, Calixarene, Electrospin Coating, Fluorescence, Nanotechnology, Biomedical, Scaffold, Tissue Engineering, Pharmaceuticals

Kaynak

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

18

Sayı

8

Künye