ANCA Positive Propylthiouracil Induced, Pyoderma Gangrenosum
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Dosyalar
Tarih
2006
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Editrice Kurtis S R L
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Drugs from almost every class of pharmaceutic agent have been reported to cause vasculitis. Vasculitis among patients taking propylthiouracil (PTU) has been reported since 1950s (1) but relation of p-ANCA positive vasculitis in patients with hyper- thyroidism on PTU treatment was first reported by Stankus and Johnson in 1992 (2). In majority of the cases, approximately 80%, pyo- derma gangrenosum (PG) has been associated with systematic diseases such as ulcerative colitis, Crohn's disease, rheumatoid arthritis, Behcet's syndrome, monoclonal gammapathy (especially IgA) and chron- ic myeloid leukemia (3). There were also rare reports about drug induced PG reported to associate with iodide, bromide, isotretinoin, granulocyte colony stimulating factor and granulocyte-macrophage colony stimulating factor (4). PTU induced p-AN?A associated PG has been first reported by Darben et al. (5) in 1999. Hong et al. (6) reported second case in 2004. Here we report another case of PG in a p- ANCA positive patient treated for years with PTU for hyperthyroidism due to Graves' disease.
Açıklama
Anahtar Kelimeler
Kaynak
Journal of Endocrinological Investigation
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
29
Sayı
Künye
Kaya, A., Dikbas, O., Kisakol, G., Gonen, S., Gungor, K., (2006). ANCA Positive Propylthiouracil Induced, Pyoderma Gangrenosum. Journal of Endocrinological Investigation, (29), 575-576.