Insufficiency of positive airway pressure treatment on increased mean platelet volume: a prospective controlled study in patients with obstructive sleep apnea syndrome

Basit Öğe Kaydı
dc.contributor.authorUlusoy, Bülent
dc.contributor.authorOğuzhan, Tolga
dc.contributor.authorAkyol, Mesut
dc.contributor.authorBozdemir, Kazım
dc.contributor.authorÇiftçi, Bülent
dc.contributor.authorKorkmaz, Mehmet Hakan
dc.date.accessioned2020-03-26T20:19:56Z
dc.date.available2020-03-26T20:19:56Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: To analyze the association between obstructive sleep apnea syndrome (OSAS) and some hematological variables such as mean platelet volume (MPV), platelet distribution width (PDW), and the impact of positive airway pressure (PAP) treatment on these parameters. Methods: The participants of the present prospective study consist of 36 OSAS patients diagnosed with polysomnography and recommended PAP treatment and 30 healthy members as the control group. Complete blood analyses were conducted to the patient group twice; before the initiation of the PAP treatment and 1 month after regular PAP use. The control group was administered a complete blood analyses only once. Patient and control group were compared in terms of various parameters such as MPV, PDW, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), white blood cell (WBC) values, and platelet counts. Results: MPV value of the patient group was before and after PAP treatment significantly higher than the control group (respectively; Z = 2.246; p = 0.025, and Z = 2.033; p = 0.042). However, there were no statistically significant differences in the values before and after PAP treatment in the patient group (Z = 0.727; p = 0.467). In terms of platelet numbers and PDW values, no significant differences were determined (p > 0.05). Conclusion: MPV value was significantly elevated in OSAS patients. However, the 1 month of PAP treatment was insufficient in decreasing elevated MPV values. © 2019, Springer Nature Switzerland AG.en_US
dc.identifier.doi10.1007/s11325-019-01918-zen_US
dc.identifier.issn1520-9512en_US
dc.identifier.pmid31392572en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s11325-019-01918-z
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38451
dc.identifier.wosWOS:000559837000012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Verlagen_US
dc.relation.ispartofSleep and Breathingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectContinuous positive airway pressureen_US
dc.subjectMean platelet volumeen_US
dc.subjectObstructive sleep apnea syndromeen_US
dc.subjectThrombosisen_US
dc.titleInsufficiency of positive airway pressure treatment on increased mean platelet volume: a prospective controlled study in patients with obstructive sleep apnea syndromeen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu