Enantioselective hydrolysis of (R,S)-Naproxen methyl ester using Candida rugosa lipase with calix[4]arene derivatives

Küçük Resim Yok

Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

SPRINGER

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Candida rugosa lipase has been immobilized on a variety of calix[4] arene derivatives using the sol-gel encapsulation technique, and the catalytic activities of the resulting encapsulated lipases towards the hydrolysis of p-nitrophenyl palmitate and the hydrolytic kinetic resolution of racemic Naproxen methyl ester were evaluated using standard techniques. The results revealed that the calix[4]arene- based immobilized encapsulated lipases 5-CRL and 6-CRL gave higher levels of enantioselectivity and conversion than the free encapsulated lipase.

Açıklama

Anahtar Kelimeler

Calix[4]arene, Candida rugosa lipase, Enantioselectivity, Naproxen, Sol-gel encapsulation

Kaynak

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

81

Sayı

01.02.2020

Künye