Enantioselective hydrolysis of (R,S)-Naproxen methyl ester using Candida rugosa lipase with calix[4]arene derivatives
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SPRINGER
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Candida rugosa lipase has been immobilized on a variety of calix[4] arene derivatives using the sol-gel encapsulation technique, and the catalytic activities of the resulting encapsulated lipases towards the hydrolysis of p-nitrophenyl palmitate and the hydrolytic kinetic resolution of racemic Naproxen methyl ester were evaluated using standard techniques. The results revealed that the calix[4]arene- based immobilized encapsulated lipases 5-CRL and 6-CRL gave higher levels of enantioselectivity and conversion than the free encapsulated lipase.
Açıklama
Anahtar Kelimeler
Calix[4]arene, Candida rugosa lipase, Enantioselectivity, Naproxen, Sol-gel encapsulation
Kaynak
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
81
Sayı
01.02.2020