One-Pot Facile Synthesis of PEGylated Au Nanoparticles in an Aqueous Media
Yükleniyor...
Dosyalar
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ELSEVIER SCIENCE SA
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We describe a facile protocol for the synthesis of PEGylated Au nanoparticles by simply mixing aqueous solutions of HAuCl4 and oligo(ethylene glycol) ethyl ether methacrylate. This method was applied to generate uniform multiply-twinned Au nanostructures of similar to 21 nm in diameter with high yields. Our proposed mechanism indicates that the generation of primary alcohol intermediates from the nucleophilic addition reaction of water (nucleophile) with AuIII-vinyl complex is responsible for the reduction of gold ions. This protocol was also used to synthesize Ag nanoparticles and small aggregates of Pd nanoparticles. Due to the exclusion of sophisticated synthesis of PEG containing stabilizers, additional surfactants, or reducing agents, this approach provides a remarkably simple, versatile, and environmentally benign protocol to prepare PEGylated noble-metal nanocrystals. A comparative BSA adsorption study proved the lack of non-specific binding, a common obstacle in designing biocompatible nanoparticles.
Açıklama
Anahtar Kelimeler
Oligo(ethylene glycol) ethyl ether methacrylate, Gold, Silver, Palladium, Nanoparticles, PEGylated, BSA adsorption, PEGEEM
Kaynak
Materials Chemistry and Physics
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
134
Sayı
02.03.2020
Künye
Çamlı, Ş. T., Büyükserin, F., Yavuz, C. T., Yavuz, M. S., (2012). One-Pot Facile Synthesis of PEGylated Au Nanoparticles in an Aqueous Media. Materials Chemistry and Physics, 134, 1153-1159. Doi:10.1016/j.matchemphys.2012.04.008
