Target Organ Associations in Turkish Patients With Behçet's Disease: A Cross Sectional Study by Exploratory Factor Analysis

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dc.contributor.authorTunç, Recep
dc.contributor.authorKeyman, Erkani
dc.contributor.authorMelikoğlu, Melike
dc.contributor.authorFresko, Izzet
dc.contributor.authorYazıcı, Hasan
dc.date.accessioned2020-03-26T16:45:02Z
dc.date.available2020-03-26T16:45:02Z
dc.date.issued2002
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective. To look for target organ associations in Turkish patients with Behçet's disease (BD). Methods. We studied target organ associations in 272 consecutive patients with BD. The occurrence of any of the clinical manifestations related to BD within the previous 3 months was sought by history questionnaire completed by a rheumatologist and by physical examination. Factor analysis was used to analyze the data. Results. Four factors were identified by factor analysis of variables oral and genital ulcers, erythema nodosum, papulopustular skin lesions, uveitis, superficial and deep vein thrombosis, joint, arterial, neurological, and gastrointestinal involvement; the 4 identified factors explained 69% of the original information of the matrix. There was an association between oral ulcers, genital ulcers, and erythema nodosum (Factor 1); and between superficial and deep vein thrombosis (Factor 2). Uveitis was identified as a distinct feature, and was negatively associated with erythema nodosum (Factor 3) only among the females. There was also an association between papulopustular skin lesions and joint involvement (Factor 4). Factors 2 and 3 had higher scores in males (p = 0.001 and p = 0.009, respectively) versus females. Conclusion. We studied clinical features of BD in Turkish patients. The 4 factors we identified by factor analysis differ from a previous study from Israel, probably due to different methodologies used in the 2 studies. One factor described in our study, the association between papulopustular lesions and arthritis, supports findings of our recent study. A recognized association between superficial and deep vein thrombosis was also confirmed.en_US
dc.identifier.citationTunç, R., Keyman, E., Melikoğlu, M., Fresko, I., Yazıcı, H., (2002). Target Organ Associations in Turkish Patients With Behçet's Disease: A Cross Sectional Study by Exploratory Factor Analysis. Journal of Rheumatology, 29(11), 2393-2396.
dc.identifier.endpage2396en_US
dc.identifier.issn0315-162Xen_US
dc.identifier.issue11en_US
dc.identifier.pmid12415598en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage2393en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18175
dc.identifier.volume29en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTunç, Recep
dc.language.isoenen_US
dc.relation.ispartofJournal of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBehçet's syndromeen_US
dc.subjectFactor analysisen_US
dc.subjectTarget organ associationen_US
dc.titleTarget Organ Associations in Turkish Patients With Behçet's Disease: A Cross Sectional Study by Exploratory Factor Analysisen_US
dc.typeArticleen_US

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