Quantification of Mitral Regurgitation in Anatolian Shepherd Dogs with Asymptomatic Degenerative Mitral Valve Disease

dc.contributor.authorTurgut, Kursad
dc.contributor.authorKoc, Yilmaz
dc.contributor.authorGuzelbektes, Hasan
dc.contributor.authorNaseri, Amir
dc.contributor.authorInce, Mehmet Ege
dc.contributor.authorSen, Ismail
dc.date.accessioned2020-03-26T19:25:53Z
dc.date.available2020-03-26T19:25:53Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractDegenerative mitral valvular disease (DMVD) is the most frequent cardiac disease, causing mitral regurgitation (MR) in dogs. The purpose of this study was to compare the ratio of the regurgitant jet area (RJA) to the left atrial area (LAA) (RJA/LAA) with subtracting method to quantify regurgitant volume (RegV) and regurgitant fraction (RF) in asymptomatic Anatolian Shepherd Dogs (ASHs) with DMVD. Thirty-eight ASHs with DMVD were used as experimental group. The control group consisted of 35 healthy ASHs. In 38 ASHs with DMVD (20 B1 dogs and 18 B2 dogs), the severity of MR was assessed by RJA/LAA and subtraction method. No differences were noted between the assays measuring the severity of MR by chi 2 analysis. The observed agreement between the assays was 81% for RJA/LAA vs RegV and was 73% for RJA/LAA vs RF, and the kappa statistic values for RJA/LAA vs RegV and for RJA/LAA vs RF were 0.63 (substantial agreement) and 0.50 (moderate agreement), respectively. Our results indicate that each quantification method was valuable to estimate the acuteness of the disease in ASHs with MR and all were in good accordance with the echocardiographic heart size and N-terminal Pro-Brain Natriuretic Peptide (NT-proBNP) measurements. Therefore, the each of these non-invasive methods may be functional to serially estimate the acuteness of MR in DMVD in order to monitor the progression of disease. Future studies have to evaluate, if these will be useful to anticipate the risk or time of decompensation in asymptomatic dogs. (C) 2016 PVJ. All rights reserveden_US
dc.description.sponsorshipScientific and Technical Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); Selcuk University Scientific Research Project Council (SUBAP)en_US
dc.description.sponsorshipThis study was supported by both The Scientific and Technical Research Council of Turkey (TUBITAK) and Selcuk University Scientific Research Project Council (SUBAP). We are thankful to Dr. Seref Inal for his excellent assistance to statistical analyses.en_US
dc.identifier.endpage424en_US
dc.identifier.issn0253-8318en_US
dc.identifier.issn2074-7764en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage421en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33920
dc.identifier.volume36en_US
dc.identifier.wosWOS:000385716600007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUNIV AGRICULTURE, FAC VETERINARY SCIENCEen_US
dc.relation.ispartofPAKISTAN VETERINARY JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAnatolian shepherd dogen_US
dc.subjectCanineen_US
dc.subjectCardiacen_US
dc.subjectDegenerative mitral valve diseaseen_US
dc.subjectQuantification of mitral regurgitationen_US
dc.titleQuantification of Mitral Regurgitation in Anatolian Shepherd Dogs with Asymptomatic Degenerative Mitral Valve Diseaseen_US
dc.typeArticleen_US

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