Transfusion Related Acute Lung Injury: A Severe Case Triggered with Anti-HLA Class II Antibodies in the Recipient

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dc.contributor.authorBorazan, Hale
dc.contributor.authorYosunkaya, Şebnem
dc.contributor.authorYosunkaya, Alper
dc.date.accessioned2020-03-26T18:31:59Z
dc.date.available2020-03-26T18:31:59Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractTransfusion-related acute lung injury (TRALI) is a serious clinical syndrome associated with the transfusion of plasma-containing blood components. The classic TRALI syndrome is characterized by the suddenly onset of respiratory failure within 2-6 hrs of the transfusion of a blood product, generally transient, resolves within 48-96 hrs spontaneously, and has a better prognosis. Nonetheless there is an expanded definition of TRALI syndrome up to 72 hrs, which is called delayed TRALI. The potential causes of TRALI can be explained by two distinct mechanism including the anti-leukocyte antibodies in donor plasma or in recipient plasma with the reverse mechanism, and biological response modifiers in susceptible individuals. This report highlights the succesful management of a classic TRALI case that was seen approximately two hours after the transfusion of a packed red blood cell and triggered with anti-HLA class II antibodies in the recipient with reverse mechanism accompanied by neutropenia together.en_US
dc.identifier.citationBorazan, H., Yosunkaya, Ş., Yosunkaya, A., (2012). Transfusion Related Acute Lung Injury: A Severe Case Triggered with Anti-HLA Class II Antibodies in the Recipient. Signa Vitae, 7(1), 52-56. Doi: 10.22514/SV71.042012.11
dc.identifier.doi10.22514/SV71.042012.11en_US
dc.identifier.endpage56en_US
dc.identifier.issn1334-5605en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage52en_US
dc.identifier.urihttps://dx.doi.org/10.22514/SV71.042012.11
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28587
dc.identifier.volume7en_US
dc.identifier.wosWOS:000304326700011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBorazan, Hale
dc.institutionauthorYosunkaya, Şebnem
dc.institutionauthorYosunkaya, Alper
dc.language.isoenen_US
dc.publisherPHARMAMED MADO LTDen_US
dc.relation.ispartofSigna Vitaeen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjecttransfusionen_US
dc.subjectacute lung injuryen_US
dc.subjecttransfusion related acute lung injuryen_US
dc.subjectanti HLA antibodiesen_US
dc.titleTransfusion Related Acute Lung Injury: A Severe Case Triggered with Anti-HLA Class II Antibodies in the Recipienten_US
dc.typeArticleen_US

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