The Synthesis and Reactions of Novel Pyrazole Derivatives by 4-phenylcarbonyl-5-phenyl-2,3-dihydro-2,3-furandione Reacted with Some Hydrazones

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dc.contributor.authorErdem, Ahmet
dc.contributor.authorGenc, Hasan
dc.contributor.authorSen, Nejdet
dc.contributor.authorKilincarslan, Rafet
dc.contributor.authorErdem, Emin
dc.date.accessioned2020-03-26T19:43:10Z
dc.date.available2020-03-26T19:43:10Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractWe report some novel pyrazole derivatives taking 4-phenylcarbonyl-5-phenyl-2,3-dihydro-2,3-furandione, I. For this, 4-phenylcarbonyl-5-phenyl-2,3-dihydro-2,3-furandione, 1 was reacted with benzaldehyde (2- or 4-fluorophenyl)hydrazone to give 4-benzoyl-1-(2- or 4-fluorophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid 2a,b. Pyrazol derivative containing 2-fluorophenyl group 2a was converted into carboxylic chloride derivative 3a by thionyl chloride and then the compound 4a was obtained from reaction ammonia with compound 3a. In the next step, 4-benzoyl-1-(2-fluorophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid 2a was reacted with MeOH/H2SO4, EtOH/H2SO4, 2-nitrophenylhydrazine and 3-nitrophenylydrazine to give 5a,b and 6a,b pyrazol derivatives, respectively. The structures regarding all compounds synthesized were determined by the IR, NMR and elemental analysis method.en_US
dc.description.sponsorshipSelguk University [10201091]en_US
dc.description.sponsorshipFinancial support from Selguk University (Project No: 10201091) are gratefully acknowledged.en_US
dc.identifier.endpage146en_US
dc.identifier.issn0034-7752en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35615
dc.identifier.volume68en_US
dc.identifier.wosWOS:000395499200031en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCHIMINFORM DATA S Aen_US
dc.relation.ispartofREVISTA DE CHIMIEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subject2,3-furandioneen_US
dc.subjectpyrazole-3-carboxylic aciden_US
dc.subjectnucleophilesen_US
dc.subjecthydrazonesen_US
dc.titleThe Synthesis and Reactions of Novel Pyrazole Derivatives by 4-phenylcarbonyl-5-phenyl-2,3-dihydro-2,3-furandione Reacted with Some Hydrazonesen_US
dc.typeArticleen_US

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