In vitro antiviral activities under cytotoxic doses against herpes simples type-1 and parainfluensa-3 viruses of Cicer arietinum L. (Chickpea)

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dc.contributor.authorKan, Asuman
dc.contributor.authorOzcelik, Berrin
dc.contributor.authorKartal, Murat
dc.date.accessioned2020-03-26T17:38:56Z
dc.date.available2020-03-26T17:38:56Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe objective of this study was to evaluation antiviral activities of the extracts from the seed, fruit skin and aerial parts of ten registered varieties Cicer arietinum (Chickpea) against Herpes simplex type 1 (HSV-1) and Parainfluenza-3 (PI-3) viruses. Madin-Darby Bovine Kidney and Vero cell lines were employed for antiviral assessment of the Cicer arientinum L. extracts, in which acyclovir for HSV-1 and oseltamivir for PI-3 were tested as reference drugs. This is the first report showing that C. arietinum seed extracts of Cse-5 possesses significant antiviral activity both of DNA (32 - 4 mu g ml(-1)) and RNA (32 16 mu g ml(-1)) viruses compared to the fruit skin and aerial part extracts as well as the controls. Besides, the extracts of fruit skin (Cfs-4) and aerial parts (Cap-5) showed remarkable activity against DNA viruses at 32 - 1 mu g ml-(1).en_US
dc.identifier.endpage631en_US
dc.identifier.issn1996-0816en_US
dc.identifier.issue12en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage627en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23609
dc.identifier.volume3en_US
dc.identifier.wosWOS:000275388500006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherACADEMIC JOURNALSen_US
dc.relation.ispartofAFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAntibacterialen_US
dc.subjectantifungalen_US
dc.subjectantiviral activityen_US
dc.subjectCicer arietinumen_US
dc.subjectchickpeaen_US
dc.titleIn vitro antiviral activities under cytotoxic doses against herpes simples type-1 and parainfluensa-3 viruses of Cicer arietinum L. (Chickpea)en_US
dc.typeArticleen_US

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