Prevalence of hepatitis A, B, C and E virus in adolescents with type-1 diabetes mellitus

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dc.contributor.authorAtabek M.E.
dc.contributor.authorKart H.
dc.contributor.authorErkul I.
dc.date.accessioned2020-03-26T16:46:39Z
dc.date.available2020-03-26T16:46:39Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe hypothesis for this study was that hepatitis virus infection could be associated with diabetes, because of the high frequency of injections. In this study, we aimed to determine the prevalence of hepatitis A, B, C and E viruses in type-1 diabetes mellitus. Methods: Sixty-three patients with the diagnosis of insulin-dependent diabetes mellitus and 63 healthy controls were included in this study. Serological markers of four different types of hepatitis (Anti-HAV IgM, total anti-HAV, HbsAg, anti-HBs, total anti-HBc, antiHBc IgM, anti-HCV and anti-HEV) were studied in all cases. None of the patients had a history of previous icterus or other signs of hepatitis, had received blood transfusions, or were on hemodialysis. Results: There was no difference between the patients and controls with respect to hepatitis A, B, C and E virus serology. The rate of seropositivity of patients within a month of the diagnosis was smaller than those of the patients whose diagnosis were older than one month, but the difference was not found to be statistically significant (p>0,05). Moreover, hepatitis virus infections did not seem to be related to duration of disease, nor age of onset, ketoacidosis, HbA1c, and insulin regimen. All of the sera were negative for anti-HCV in both patients and controls. Conclusion: Serological evidence of previous HAV, HBV, HCV and HEV infections was not significantly different between type-1 diabetes patients and healthy controls. Hepatitis virus infection was not associated with diabetes in spite of the high frequency of injections.en_US
dc.identifier.doi10.1515/IJAMH.2003.15.2.133en_US
dc.identifier.endpage137en_US
dc.identifier.issn0334-0139en_US
dc.identifier.issue2en_US
dc.identifier.pmid12955815en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage133en_US
dc.identifier.urihttps://dx.doi.org/10.1515/IJAMH.2003.15.2.133
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18702
dc.identifier.volume15en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherFreund Publishing House Ltden_US
dc.relation.ispartofInternational Journal of Adolescent Medicine and Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHepatitis virusesen_US
dc.subjectInsulin-dependent diabetes mellitusen_US
dc.titlePrevalence of hepatitis A, B, C and E virus in adolescents with type-1 diabetes mellitusen_US
dc.typeArticleen_US

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