The relation among to mortality rate, hospitalization period and inflammatory mediators in patients with chronic obstructive pulmonary disease attack on admission to emergency department

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dc.contributor.authorBayir A.
dc.contributor.authorBuyukunaldi P.
dc.contributor.authorKiyici A.
dc.contributor.authorKara H.
dc.date.accessioned2020-03-26T19:08:34Z
dc.date.available2020-03-26T19:08:34Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractChronic obstructive pulmonary disease (COPD) is characterized by a progressive and not completely reversible obstruction of the airways associated with an abnormal inflammatory response of the lungs to particles and noxious gases related to a systemic effect. Inflammatory processes are suggested to be involved in pathogenesis of COPD. The aim of the study was to investigate the relation among to the mortality rate, hospitalization period and inflammatory mediators of the patients with COPD attack on admission into the emergency department. A total of 87 subjects with COPD attack were contributed in this study. TNF-?, IL-6 and catalase were determined in addition to leucocyte count (WBC), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). There was no significant difference between the deceased and discharged patients in terms of WBC, ESR, CRP, IL-6, and TNF-?. However, mean catalase levels of discharged patients were significantly higher than the deceased patients (p<0.05). Significant correlations were observed between WBC and hospitalization period, and CRP and follow up period in the intensive care unit. We can suggest that catalase activities on admission into the emergency service were decreased in deceased patients who were in follow up in intensive care unit with COPD attack. High CRP and WBC levels were also related with the hospitalization period of patients with COPD attack. © 2015 OMU.en_US
dc.identifier.doi10.5835/jecm.omu.32.03.001en_US
dc.identifier.endpage101en_US
dc.identifier.issn1309-4483en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage97en_US
dc.identifier.urihttps://dx.doi.org/10.5835/jecm.omu.32.03.001
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32868
dc.identifier.volume32en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherOndokuz Mayis Universitesien_US
dc.relation.ispartofJournal of Experimental and Clinical Medicine (Turkey)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectChronic obstructive pulmonary diseaseen_US
dc.subjectHospitalizationen_US
dc.subjectInflammatory mediatoren_US
dc.subjectMortality rateen_US
dc.titleThe relation among to mortality rate, hospitalization period and inflammatory mediators in patients with chronic obstructive pulmonary disease attack on admission to emergency departmenten_US
dc.typeArticleen_US

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