The effect of measurement uncertainty for HOMA-IR in assessment of insulin resistance

dc.contributor.authorErcan, Müjgan
dc.contributor.authorCaniklioğlu, Ayşen
dc.contributor.authorOğuz, Esra Fırat
dc.contributor.authorYücel, Çiğdem
dc.contributor.authorÖzcan, Mehmet
dc.contributor.authorYılmaz, Fatma Meriç
dc.contributor.authorAbuşoğlu, Sedat
dc.date.accessioned2020-03-26T20:12:10Z
dc.date.available2020-03-26T20:12:10Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Tıbbi Biyokimya Bölümüen_US
dc.description.abstractIn this study, it is aimed to estimate not just the uncertainty measurement for the parameters of glucose and insulin having role when calculating HOMA-IR, but also true positiveness and negativeness in terms of cut-off values. The evaluation of the acceptability of the uncertainty value was also among the goals of the study. The uncertainty measurement for glucose and insulin is calculated as uncertainty measurement of HOMA-IR based on Eurochem/CITAC Guide CG 4. The uncertainty measurement for glucose and insulin was estimated as 3.83% and 4.16%, respectively. The measurement uncertainty for the calculated test HOMA-IR was calculated with cut-off values as 27% (0.27). Based on the cut-off value for HOMA-IR of 2.5%, IR() and IR(-) patients were 155 and 265, respectively. If the uncertainty measurement for HOMA-IR was added to its calculation, the cut-off value was detected as 2.23-2.77%. We reported the measurement uncertainty of the calculated test HOMA-IR at 95 % CI as 0.27 between 2.23 - 2.77. Especially for the tests used for screening; determination of cut-off values as a range including measurement uncertainty instead of a single value will be more suitable. No data is found in the literature for the calculated test HOMA-IR up to date.en_US
dc.identifier.citationErcan, M., Caniklioğlu, A., Oğuz, E. F., Yücel, Ç., Özcan, M., Yılmaz, F. M., Abuşoğlu, S. (2019). The effect of measurement uncertainty for HOMA-IR in assessment of insulin resistance. Medicine Science, 8(1), 32-36.
dc.identifier.doi10.5455/medscience.2018.07.8905en_US
dc.identifier.endpage36en_US
dc.identifier.issn2147-0634en_US
dc.identifier.issn2147-0634en_US
dc.identifier.issue1en_US
dc.identifier.startpage32en_US
dc.identifier.urihttps://dx.doi.org/10.5455/medscience.2018.07.8905
dc.identifier.urihttp://www.trdizin.gov.tr/publication/paper/detail/TXpBNE1qWXlNZz09
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37369
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorAbuşoğlu, Sedat
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAcil Tıpen_US
dc.subjectAdli Tıpen_US
dc.subjectAlerjien_US
dc.subjectAnatomi ve Morfolojien_US
dc.subjectAndrolojien_US
dc.subjectAnestezien_US
dc.subjectBiyofiziken_US
dc.subjectBiyokimya ve Moleküler Biyolojien_US
dc.subjectBiyolojien_US
dc.subjectBiyoteknoloji ve Uygulamalı Mikrobiyolojien_US
dc.subjectCerrahien_US
dc.subjectDermatolojien_US
dc.subjectEndokrinoloji ve Metabolizmaen_US
dc.subjectEnfeksiyon Hastalıklarıen_US
dc.subjectFizyolojien_US
dc.subjectGastroenteroloji ve Hepatolojien_US
dc.subjectGenel ve Dahili Tıpen_US
dc.subjectGeriatri ve Gerontolojien_US
dc.subjectGöz Hastalıklarıen_US
dc.subjectHalk ve Çevre Sağlığıen_US
dc.subjectHematolojien_US
dc.subjectHücre Biyolojisien_US
dc.subjectİmmünolojien_US
dc.subjectKadın Hastalıkları ve Doğumen_US
dc.subjectKalp ve Kalp Damar Sistemien_US
dc.subjectKlinik Nörolojien_US
dc.subjectKulaken_US
dc.subjectBurunen_US
dc.subjectBoğazen_US
dc.subjectMikrobiyolojien_US
dc.subjectNörolojik Bilimleren_US
dc.subjectOdyoloji ve Konuşma-Dil Patolojisien_US
dc.subjectOnkolojien_US
dc.subjectOrtopedien_US
dc.subjectPatolojien_US
dc.subjectPediatrien_US
dc.subjectPeriferik Damar Hastalıklarıen_US
dc.subjectPsikiyatrien_US
dc.subjectRadyolojien_US
dc.subjectNükleer Tıpen_US
dc.subjectTıbbi Görüntülemeen_US
dc.subjectRehabilitasyonen_US
dc.subjectRomatolojien_US
dc.subjectSağlık Bilimleri ve Hizmetlerien_US
dc.subjectSolunum Sistemien_US
dc.subjectSpor Bilimlerien_US
dc.subjectTamamlayıcı ve Entegre Tıpen_US
dc.subjectTemel Sağlık Hizmetlerien_US
dc.subjectTıbbi Araştırmalar Deneyselen_US
dc.subjectTıbbi Etiken_US
dc.subjectTıbbi İnformatiken_US
dc.subjectTıbbi Laboratuar Teknolojisien_US
dc.subjectTransplantasyonen_US
dc.subjectTropik Tıpen_US
dc.subjectÜroloji ve Nefrolojien_US
dc.subjectYoğun Bakımen_US
dc.subjectTıpen_US
dc.titleThe effect of measurement uncertainty for HOMA-IR in assessment of insulin resistanceen_US
dc.typeArticleen_US

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