Epidural Administration of Midasolam for Chronic Central Pain and Spasticity in Spinal Cord Injured Patients

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dc.contributor.authorÖzerbil, O. M.
dc.contributor.authorDuman, A.
dc.contributor.authorYosunkaya, A.
dc.contributor.authorBayram, A.
dc.contributor.authorÜstün, M. E.
dc.date.accessioned2020-03-26T16:25:30Z
dc.date.available2020-03-26T16:25:30Z
dc.date.issued1997
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn the patients with spinal cord injury (SCI) chronic pain and spasticity affect significantly both the efficacy of rehabilitation and the quality of life. Recently it was shown that intrathecally and epidurally administered midasolam has analgesic and antispatic effects in both animals and humans so that it constitutes an alternative to be used in patients with SCI. In this study, four paraplegics who suffered from chronic central pain and spasticity in their lower extremities were given midasolan 6 times daily (dose 40 ?g/kg dose dissolved in 10 ml normal saline) via lumbar epidural catheter using pain management provider. Spasticity was monitored by means of a modified Ashwort scale, and pain evaluation was performed by face scale and VAS. The patients were hospitalized at least for two weeks and were observed for the efficacy of the drug. Although epidural administration of midasolam relieved both central pain and spasticity, it's efficacy on central pain was more pronounced. There were no significant side effects is any patient. We propose that midasolam may be given by epidural catheter or implantable drug pump for the treatment of central pain and/or spinal spasticity in spinal cord injured patients.en_US
dc.identifier.citationÖzerbil, O. M., Duman, A., Yosunkaya, A., Bayram, A., Üstün, M. E., (1997). Epidural Administration of Midasolam for Chronic Central Pain and Spasticity in Spinal Cord Injured Patients. Journal of Rheumatology and Medical Rehabilitation, 8(4), 328-330.
dc.identifier.endpage330en_US
dc.identifier.issn1300-0691en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage328en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16610
dc.identifier.volume8en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÖzerbil, O. M.
dc.institutionauthorDuman, A.
dc.institutionauthorYosunkaya, A.
dc.institutionauthorBayram, A.
dc.institutionauthorÜstün, M. E.
dc.language.isotren_US
dc.relation.ispartofJournal of Rheumatology and Medical Rehabilitationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCentral painen_US
dc.subjectMidasolamen_US
dc.subjectSpasticityen_US
dc.subjectSpinal cord injuriesen_US
dc.titleEpidural Administration of Midasolam for Chronic Central Pain and Spasticity in Spinal Cord Injured Patientsen_US
dc.title.alternativeSpinal Kord Yaralı Hastalarda Kronik Santral Ağrı ve Spastisite İçin Epidural Midazolam Uygulanımıen_US
dc.typeArticleen_US

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