Effects of trace element levels on platelet aggregation
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Date
2004
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
HUMANA PRESS INC
Access Rights
info:eu-repo/semantics/openAccess
Abstract
Platelet aggregation was measured by an optical method in 32 patients with iron-deficiency anemia at the time of diagnosis and after a period of Supplementation with iron. Epinephrine- and adenosine diphosphate-induced platelet aggregation were lower in anemic patients than in the controls (p<0.05). After iron-supplementation therapy, these values showed no significant differences. If induced by collagen or ristocetin, platelet aggregation was the same for patients and controls, but increased after treatment of patients (p<0.05). The plasma zinc values did not show significant differences among the subjects included in this study. These results show that iron is involved in the enzymatic systems that regulate platelet aggregation. The exact nature of this interaction is still to be determined.
Description
Keywords
platelet aggregation, trace elements, iron-deficiency anemia, iron supplementation
Journal or Series
BIOLOGICAL TRACE ELEMENT RESEARCH
WoS Q Value
Q4
Scopus Q Value
Volume
99
Issue
01.03.2020
