Estimation of in vitro neuroprotective properties and quantification of rutin and fatty acids in buckwheat (Fagopyrum esculentum Moench) cultivated in Turkey

Basit Öğe Kaydı
dc.contributor.authorGulpinar, Ali Rifat
dc.contributor.authorOrhan, Ilkay Erdogan
dc.contributor.authorKan, Asuman
dc.contributor.authorSenol, Fatma Sezer
dc.contributor.authorCelik, Sadiye Ayse
dc.contributor.authorKartal, Murat
dc.date.accessioned2020-03-26T18:25:34Z
dc.date.available2020-03-26T18:25:34Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBuckwheat (Fagopyrum esculentum Moench, Polygonaceae) is a popular food crop plant from Polygonaceae. In this study, we investigated the ethyl acetate and ethanol extracts of the seed, stem, and aerial parts of the plant for their neuroprotective effect through acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory and antioxidant activity. Antioxidant activity was measured using the scavenging activity tests against 2,2-diphenyl-1-picrylhydrazyl (DPPH), N,N-dimethyl-p-phenylendiamine (DMPD), superoxide, and hydrogen peroxide radicals and the metal-related methods; metal-chelating capacity and ferric-reducing antioxidant power (FRAP), and phosphomolibdenum-reducing antioxidant power (PRAP) assays. Total phenol and flavonoid contents were calculated spectrophotometrically. Chemical composition of the seed oil was identified by gas chromatography-mass spectrometry (GC-MS) and rutin was quantified by liquid chromatography-mass spectrometry (LC-MS). The extracts were more active against butyrylcholinesterase and highly able to scavenge DPPH. The ethyl acetate extract of the aerial parts and the ethanol extract of the stems displayed a remarkable effect in the FRAP assay. None of the extracts had capacity to chelate the iron. According to LC-MS analysis, the richest plant part in terms of rutin was found to be the aerial parts. GC-MS analysis revealed that the seed oil was dominated by oleic (33.15%), linoleic (31.93%), and palmitic (13.15%) acids. (c) 2011 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)en_US
dc.description.sponsorshipThe authors would like thank to Dr. Ivan Salamon from Department of Ecology, Presov University (Slovak Repubic) for providing the buckwheat seeds. F.S. Senol expresses her sincere thanks to the Scientific and Technological Research Council of Turkey (TUBITAK) for the scholarship provided her for Ph.D. program.en_US
dc.identifier.doi10.1016/j.foodres.2011.08.011en_US
dc.identifier.endpage543en_US
dc.identifier.issn0963-9969en_US
dc.identifier.issn1873-7145en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage536en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.foodres.2011.08.011
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28026
dc.identifier.volume46en_US
dc.identifier.wosWOS:000302888400013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherELSEVIERen_US
dc.relation.ispartofFOOD RESEARCH INTERNATIONALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBuckwheaten_US
dc.subjectFagopyrum esculentumen_US
dc.subjectCholinesterase inhibitionen_US
dc.subjectAntioxidant activityen_US
dc.subjectRutinen_US
dc.subjectSeed oilen_US
dc.subjectFatty acidsen_US
dc.titleEstimation of in vitro neuroprotective properties and quantification of rutin and fatty acids in buckwheat (Fagopyrum esculentum Moench) cultivated in Turkeyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu