A Study on Effect of Melatonin in Dyslipidemia Caused by Experimentally Diabetes

Basit Öğe Kaydı
dc.contributor.authorUluışık, Deniz
dc.contributor.authorKeskin, Ercan
dc.contributor.authorHatipoğlu, Durmuş
dc.date.accessioned2023-09-02T14:31:38Z
dc.date.available2023-09-02T14:31:38Z
dc.date.issued2019 Nisanen_US
dc.departmentSelçuk Üniversitesi, Veteriner Fakültesi, Temel Bilimler Bölümüen_US
dc.description.abstractIn this study, it was aimed to determine the effects of melatonin application on lipid profile in streptozotocin-induced diabetic rats. Animals in control group were not any treatment. Melatonin group animals received 50 mg/kg melatonin intraperitoneally in daily for eight weeks. Diabetes was induced by subcutaneous injections of streptozotocin at dose of 40 mg/kg for two days as a single dose per day in diabetes group animals. Animals in Diabetes+Melatonin group were made diabetic by streptozotocin in the same way and then these animals received 50 mg/kg melatonin intraperitoneally in daily for eight weeks. In blood samples taken from all animals, TNF-?, triglyceride, total cholesterol, LDL and HDL were determined. In diabetes group, TNF-? level were high (p<0.05). The changes in TNF-? level with melatonin application to diabetic rats were important (p<0.05). In diabetic rats, triglyceride and LDL levels were found to be enhanced compared to control group (p<0.05), HDL level was significantly low (p<0.05), while the change in total cholesterol level was not important. With the melatonin application to diabetic rats, HDL level was found to be higher (p<0.05) and LDL level was lower than diabetes group (p<0.05). It was concluded that the administration of melatonin to streptozotocin-induced diabetic rats may have positive effects on lipid profile.en_US
dc.identifier.citationUluışık, D., Keskin, E., Hatipoğlu, D., (2019). A Study on Effect of Melatonin in Dyslipidemia Caused by Experimentally Diabetes. Turkish Journal of Sport and Exercise, 21(1), 117-121. DOI: 10.15314/tsed.541834en_US
dc.identifier.doi10.15314/tsed.541834en_US
dc.identifier.endpage121en_US
dc.identifier.issn2147-5652en_US
dc.identifier.issue1en_US
dc.identifier.startpage117en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/50403
dc.identifier.volume21en_US
dc.institutionauthorUluışık, Deniz
dc.institutionauthorKeskin, Ercan
dc.institutionauthorHatipoğlu, Durmuş
dc.language.isoenen_US
dc.publisherSelçuk Üniversitesien_US
dc.relation.ispartofTurkish Journal of Sport and Exerciseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDiabetesen_US
dc.subjectmelatoninen_US
dc.subjectTNF-αen_US
dc.subjectlipid profileen_US
dc.subjectratsen_US
dc.titleA Study on Effect of Melatonin in Dyslipidemia Caused by Experimentally Diabetesen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Spor-17.pdf
Boyut:
629.99 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Dergi Yayın Koleksiyonu
Vet. Fak. Temel Bilimler/Makale Koleksiyonu