New insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae)

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dc.contributor.authorSaleem, H.
dc.contributor.authorZengin, Gökhan
dc.contributor.authorKhan, K. U. R.
dc.contributor.authorAhmad, I.
dc.contributor.authorWaqas, M.
dc.contributor.authorMahomoodally, Mohamad Fawzi
dc.contributor.authorRengasamy, K. R. R.
dc.date.accessioned2020-03-26T20:19:58Z
dc.date.available2020-03-26T20:19:58Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study sets out to probe into total bioactive contents, UHPLC-MS secondary metabolites profiling, antioxidant (DPPH, ABTS, FRAP, CUPRAC, phosphomolybdenum and metal chelating) and enzyme inhibitory (acetylcholinesterase- AChE, butyrylcholinesterase- BChE, ?-amylase, ? glucosidase, and tyrosinase) activities of methanol extract of Aerva javanica, also known as desert cotton or Kapok bush. Aerva javanica contains considerable phenolic (44.79 ± 3.12 mg GAE/g) and flavonoid (28.86 ± 0.12 mg QE/g) contents which tends to correlate with its significant antioxidant potential for ABTS, FRAP and CUPRAC assays with values of 101.41 ± 1.18, 124.10 ± 1.71 and 190.22 ± 5.70 mg TE/g, respectively. The UHPLC-MS analysis identified the presence of 45 phytochemicals belonging to six major groups: phenolic, flavonoids, lignin, terpenes, glycoside and alkaloid. Moreover, the plant extract also showed potent inhibitory action against AChE (3.73 ± 0.22 mg GALAE/g), BChE (3.31 ± 0.19 mg GALAE/g) and tyrosinase (126.05 ± 1.77 mg KAE/g). The observed results suggest A. javanica could be further explored as a natural source of bioactive compounds. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.en_US
dc.identifier.doi10.1080/14786419.2019.1587427en_US
dc.identifier.issn1478-6419en_US
dc.identifier.pmid30919661en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://dx.doi.org/10.1080/14786419.2019.1587427
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38461
dc.identifier.wosWOS:000613796200021en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofNatural Product Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAerva javanicaen_US
dc.subjectantioxidanten_US
dc.subjectenzyme inhibitionen_US
dc.subjectkapok bushen_US
dc.subjectsecondary metabolitesen_US
dc.titleNew insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae)en_US
dc.typeArticleen_US

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