The Effect of Methyldopa Treatment on Uterine, Umblical and Fetal Middle Cerebral Artery Blood Flows in Preeclamptic Patients

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dc.contributor.authorGünenç, Oğuzhan
dc.contributor.authorÇiçek, N.
dc.contributor.authorGörkemli, Hayriye
dc.contributor.authorÇelik, Çetin
dc.contributor.authorAcar, Ali
dc.contributor.authorAkyürek, Cemalettin
dc.date.accessioned2020-03-26T16:45:02Z
dc.date.available2020-03-26T16:45:02Z
dc.date.issued2002
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe purpose of this study was to evaluate the efficacy of methyldopa in the treatment of preeclamptic patients. This study was performed on 24 preeclamptic women who were in between 25-36 weeks of gestational age. 24 healthy pregnant women were taken as control group. Before starting treatment, 24 preeclamptic patients were examined with Doppler ultrasound. Pulsatility index, resistance index, systolic/diastolic ratio of uterine, umblical and fetal middle cerebral arteries were measured. Preeclamptic patients were treated with totally 1 g methyldopa per day. After 7 d, patients were reexamined with Doppler ultrasound. The effect of methyldopa on uterine, umblical and fetal middle cerebral artery blood flows were detected. Only one control with Doppler ultrasound was done to the healthy pregnant women. Before methyldopa treatment to the preeclamptic women, pulsatility index (PI), resistance index (RI) and systolic/diastolic ratio (S/D) on uterine and umblical arteries were significantly higher than the control group. However, fetal middle cerebral artery (MCA) values were significantly lower than the control group. When Doppler results of preeclamptic patients before and after the methyldopa treatment were compared, no significant differences in terms of Pulsatility Index, Resistance IndexI and S/D ratio of umblical and fetal middle cerebral arteries were found. However, the results of uterine artery were significantly lower after the treatment in preeclamptic patients. Treatment with methyldopa lowered the uterine artery resistance in preeclamptic patients but did not effect the resistance of umblical and fetal middle cerebral artery.en_US
dc.identifier.citationGünenç, O., Çiçek, N., Görkemli, H., Çelik, Ç., Acar, A., Akyürek, C., (2002). The Effect of Methyldopa Treatment on Uterine, Umblical and Fetal Middle Cerebral Artery Blood Flows in Preeclamptic Patients. Archives of Gynecology and Obstetrics, (266), 141-144. Doi: 10.1007/s004040100214
dc.identifier.doi10.1007/s004040100214en_US
dc.identifier.endpage144en_US
dc.identifier.issn0932-0067en_US
dc.identifier.pmid12197552en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage141en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s004040100214
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18177
dc.identifier.volume266en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGünenç, Oğuzhan
dc.institutionauthorÇiçek, N.
dc.institutionauthorGörkemli, Hayriye
dc.institutionauthorÇelik, Çetin
dc.institutionauthorAcar, Ali
dc.institutionauthorAkyürek, C.
dc.language.isoenen_US
dc.relation.ispartofArchives of Gynecology and Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDoppler ultrasounden_US
dc.subjectMethyldopaen_US
dc.subjectPreeclampsiaen_US
dc.titleThe Effect of Methyldopa Treatment on Uterine, Umblical and Fetal Middle Cerebral Artery Blood Flows in Preeclamptic Patientsen_US
dc.typeArticleen_US

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