Fentanyl Added to Bupivacaine 0.05% or Ropivacaine 0.05% in Patient-Controlled Epidural Analgesia in Labour
Küçük Resim Yok
Tarih
2002
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Greenwich Medical Media Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background and objective: Epidural analgesia is the most effective method for pain relief during labour. The aim was to elucidate the efficacy of ropivacaine 0.05% and bupivacaine 0.05%, which were both combined with fentanyl 0.00015% to provide analgesia in labour. Methods: Forty nulliparous females were enrolled into the study. After insertion of an epidural catheter, patients were randomly assigned into two groups. Once the os uteri had dilated to 4-5 cm, a bolus of bupivacaine 0.125% 10 mL + fentanyl 50 mug (1 mL) in Group 1 patients, and ropivacaine 0.125% 10 mL + fentanyl 50 mug (1 mL) in Group 2 patients was administered via the epidural catheter. Then, patient-controlled epidural analgesia was started with a basal infusion of bupivacaine 0.05% 10 mL h(-1) + fentanyl 0.00015% 1.5 mug mL(-1) in Group 1, and ropivacaine 0.05% + fentanyt 1.5 mug mL(-1) in Group 2. When needed, a 10 mL bolus infusion could be given and the lockout time was 20 min. Maternal and fetal haemodynamic variables were monitored before induction and subsequently at 5 min intervals. Using a visual analogue scale assessed the degree of pain. Results: Maternal haemodynamic variables and Apgar scores were not different between the two groups. The second stage of the tabour was shorter in Group 2 (P < 0.01). There were no significant differences in patients' assessment of motor block or mode of delivery between groups. Conclusions: An epidural infusion (10 mL h(-1)) of bupivacaine 0.05% or ropivacaine 0.05% together with fentanyl 1.5 μg mL(-1) provided good and safe analgesia during tabour.
Açıklama
Anahtar Kelimeler
analgesia, epidural, analgesia, patient-controlled, local anaesthetics, bupivacaine, ropivacaine, opioids, fentanyl, pregnancy, labour
Kaynak
European Journal of Anaesthesiology
WoS Q Değeri
Q2
Scopus Q Değeri
Cilt
19
Sayı
4
Künye
Pirbudak, L., Tuncer, S., Koçoğlu, H., Göksu, S., Çelik, C., (2002). Fentanyl Added to Bupivacaine 0.05% or Ropivacaine 0.05% in Patient-Controlled Epidural Analgesia in Labour. European Journal of Anaesthesiology, 19(4), 271-275. Doi: 10.1017/S0265021502000431