Realities and expectations of pharmacogenomics and personalized medicine: Impact of translating genetic knowledge into clinical practice
Küçük Resim Yok
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The implementation of genetic data for a better prediction of response to medications and adverse drug reactions is becoming a reality in some clinical fields. However, to be successful, personalized medicine should take advantage of an informational structured framework of genetic, phenotypic and environmental factors in order to provide the healthcare system with useful tools that can optimize the effectiveness of specific treatment. The impact of personalized medicine is potentially enormous, but the results that have so far been gathered are often difficult to translate into clinical practice. In this article we have summarized the most relevant applications of pharmacogenomics on diseases to which they have already been applied and fields in which they are currently emerging. The article provides an overview of the opportunities and shortcomings of the implementation of genetic information into personalized medicine and its full adoption in the clinic. In the second instance, it provides readers from different fields of expertise with an accessible interpretation to the barriers and opportunities in the use/adoption of pharmacogenomic testing between the different clinical areas. © 2010 Future Medicine Ltd.
Açıklama
Anahtar Kelimeler
adverse drug reaction, cancer, cardiovascular disease, genetic test, infectious disease, personalized medicine, pharmacogenomics, psychiatry
Kaynak
Pharmacogenomics
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
11
Sayı
8
