Influence of Exercise on Leptin, Adiponectin and Quality of Life in Type 2 Diabetics

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dc.contributor.authorDede, Nesrin Dogan
dc.contributor.authorIpekci, Suleyman Hilmi
dc.contributor.authorKebapcilar, Levent
dc.contributor.authorArslan, Mihriban
dc.contributor.authorKurban, Sevil
dc.contributor.authorYildiz, Mustafa
dc.contributor.authorGonen, Mustafa Sait
dc.date.accessioned2020-03-26T19:06:08Z
dc.date.available2020-03-26T19:06:08Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: This study aimed to investigate the influence of aerobic exercise on the quality of life and leptin and adiponectin levels in patients with type 2 diabetes mellitus. Material and Method: Patients were randomized into two groups: aerobic exercise-training and control group. Parameters were assessed at baseline and end of the twelve-week follow-up for 60 type 2 diabetic patients who completed the program. The 36-item Short Form Health Survey was administered to the patients. Results: The exercise-training group results showed a decrease in adiponectin and leptin levels, a reduction of waist circumference and percentage of body fat (p=0.007, 0.023, 0.012 and 0.048, respectively). The leptin levels in the aerobic exercise group were positively correlated with body mass index (r=0.303, p=0.021) and percentage of body fat (r=0.371, p=0.005); they were negatively correlated with physical problems (r=-0.482; p=0.009) and pain (r=-0.540; p=0.003). Exercise led to statistically significant improvements in the SF-36 physical functioning and mental health subscales (p=0.020 and 0.023, respectively). Discussion: The association of better HbA1c, waist circumference, and percentage of body fat with improved mental and physical scores may be related to a decrease in leptin levels, despite a significant reduction in serum adiponectin levels.en_US
dc.identifier.doi10.4274/tjem.2564en_US
dc.identifier.endpage13en_US
dc.identifier.issn1301-2193en_US
dc.identifier.issue1en_US
dc.identifier.pmid#YOKen_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage7en_US
dc.identifier.urihttps://dx.doi.org/10.4274/tjem.2564
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32235
dc.identifier.volume19en_US
dc.identifier.wosWOS:000362601400003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofTURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAdiponectinen_US
dc.subjectexerciseen_US
dc.subjectleptinen_US
dc.subjectSF-36en_US
dc.subjecttype 2 diabetes mellitusen_US
dc.titleInfluence of Exercise on Leptin, Adiponectin and Quality of Life in Type 2 Diabeticsen_US
dc.typeArticleen_US

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