Effect of Dexmedetomidine on Pain Caused by Injection of Propofol

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dc.contributor.authorŞarkılar, G.
dc.contributor.authorKara, I.
dc.contributor.authorDuman, A.
dc.contributor.authorAygın, F.
dc.contributor.authorÖkeşli, S.
dc.date.accessioned2020-03-26T18:32:17Z
dc.date.available2020-03-26T18:32:17Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: This study was designed to assess the local and systemic effects of two different pre-anesthetic infusion dose of dexmedetomidine in preventing propofol injection pain. Material and Method: Two hundred fifty adults were assigned into five groups. Before injection of propofol, group 1 (placebo n=50) received an infusion of saline solution, group 2 (n=50) received 0.5 ?g kg -1 of dexmedetomidine and group 3 (n=50) received 1 ?g kg -1 of dexmedetomidine from the same vein. Group 4 (n=50) received 0.5 ?g kg -1 of dexmedetomidine and group 5 (n=50) received 1 ?g kg -1 dexmedetomidine followed by an injection of propofol from a vein located in the opposite hand. Pain assessment was made immediately after propofol injection. Results: Two hundred twenty five patients completed the study. The number of patients who suffered from any degree of pain was significantly high when compared to dexmedetomidine group (p=0.05). When compared with placebo and opposite hand, administering dexmedetomidine from the same vein was more efficient to prevent propofol pain (p=0.003). 1 ?g kg -1 of dexmedetomidine was similar to 0.5 ?g kg -1 of dexmedetomidine in preventing propofol pain.Conclusion: Dexmedetomidine infusions in pre-anesthetic sedative doses of 0.5 ?g kg -1 and 1 ?g kg -1 decrease the incidence of propofol injection pain compared to placebo.en_US
dc.identifier.citationŞarkılar, G., Kara, I., Duman, A., Aygın, F., Ökeşli, S., (2012). Effect of Dexmedetomidine on Pain Caused by Injection of Propofol. Nobel Medicus, 8(1), 83-88.
dc.identifier.endpage88en_US
dc.identifier.issn1305-2381en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage83en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28660
dc.identifier.volume8en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorŞarkılar, G.
dc.institutionauthorKara, I.
dc.institutionauthorDuman, A.
dc.institutionauthorAygın, F.
dc.institutionauthorÖkeşli, S.
dc.language.isoenen_US
dc.relation.ispartofNobel Medicusen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDexmedetomidineen_US
dc.subjectPainen_US
dc.subjectPropofolen_US
dc.titleEffect of Dexmedetomidine on Pain Caused by Injection of Propofolen_US
dc.title.alternativeDeksmedetomidinin Propofol Enjeksiyon Ağrısına Etkisien_US
dc.typeArticleen_US

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