COMPARISON OF BONE TURNOVER MARKERS BETWEEN MALE SMOKER AND NON-SMOKER

Basit Öğe Kaydı
dc.contributor.authorKargin, Nisa Cetin
dc.contributor.authorMarakoglu, Kamile
dc.contributor.authorUnlu, Ali
dc.contributor.authorKebapcilar, Levent
dc.contributor.authorKorucu, Emine Nedime
dc.date.accessioned2020-03-26T19:23:23Z
dc.date.available2020-03-26T19:23:23Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIntroduction: Osteoporosis is the most frequently seen metabolic bone disease. Smoking has long been defined as a changeable risk factor in life style for both bone loss and fractures. This study is aimed to compare of the bone turnover markers between smoker and non-smoker male. Materials and methods: In this cross-sectional and descriptive study, 85 smoker males were allocated to the case group, while 85 non-smoker males were allocated to the control group. Osteocalcin (OC) and osteoprotogerin (OPG) analyzed among bone formation parameters, while RANKL (Receptor activator of nuclear factor kappa-B ligand) and CTX (C-terminal telopeptide) were studied among the bone destruction parameters alongside with TSH (Thyroid-Stimulating Hormone), Ca (Calcium), P (Phosphorus), PTH (Parathyroid Hormone), ALP(Alkaline Phosphatase), TT (Total Testosterone), and vitamin D parameters that affect bone mineral density. Results: It was found that the smoker group's CTX level (50.30+/-26.97 ng/ml) was statistically significant lower than that of the non-smoker group (65.10+/-42.41 ng/ml. (p=0.007) The average serum PTH level of the smoker and non-smoker groups were 23.75+/-9.88 pg/ml and 31.35+/-13.15 pg/ml respectively and the related average of the non-smoker group was statistically higher than that of the smoker group (p=0.000). It was found that the smoker group's vitamin D (16.75+/-8.73 ng/ml) was statistically significant lower than that of the non-smoker group (19.50+/-8.97 ng/ml (p=0.044). Conclusions: The study supports the fact that one of the risk factors for osteoporosis is smoking and it negatively affects bone formation as well. It should be noted that osteoporosis is a significant health issue not only for older men but also for middle-aged male smokers and the necessary support for smoking cessation should be offered.en_US
dc.description.sponsorshipSelcuk University Scientific Research and Projects Comittee [13102005]en_US
dc.description.sponsorshipSelcuk University Scientific Research and Projects Comittee funded this study (Project Number: 13102005).en_US
dc.identifier.endpage323en_US
dc.identifier.issn0393-6384en_US
dc.identifier.issn2283-9720en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage317en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33376
dc.identifier.volume32en_US
dc.identifier.wosWOS:000375338000007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCARBONE EDITOREen_US
dc.relation.ispartofACTA MEDICA MEDITERRANEAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCigaretteen_US
dc.subjectosteoporosisen_US
dc.subjectbone turnoveren_US
dc.subjectsmokingen_US
dc.titleCOMPARISON OF BONE TURNOVER MARKERS BETWEEN MALE SMOKER AND NON-SMOKERen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu