Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta

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dc.authorid0000-0001-5094-2520
dc.contributor.authorSarıkürkçü, Cengiz
dc.contributor.authorCengiz, Mustafa
dc.contributor.authorKüçükyumru, Ahmet
dc.contributor.authorZengin, Gökhan
dc.date.accessioned2020-03-26T19:53:19Z
dc.date.available2020-03-26T19:53:19Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractThe members of the genus Phlomis have been traditionally used for therapeutic purposes in Turkey. In this study, the antioxidant properties of different extracts from P. leucophracta were investigated. Antioxidant properties were evaluated by different assays including free radical scavenging (DPPH assay), reducing power (potassium ferricyanide method), beta-carotene/linoleic acid, metal chelating and phosphomolybdenum. Moreover, total phenolic and flavonoid contents were detected for each extracts. Total phenolic and flavonoid contents were detected as 30.86-55.00 mg GAE/g extract and 4.93-26.09 mg QE/g extract, respectively. The methanol and water extracts exhibited higher DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging and reducing power abilities as compared to ethyl acetate and hexane extracts. The best activity was observed by the hexane extract in beta-carotene/linoleic acid assay (94.35% at 2 mg/mL). In metal chelating ability, those samples exhibited the following order (at 0.25 mg/mL concentration): Water (73.90%)>Hexane(64.87%)>Ethyl acetate(4.88%)>Methanol(2.28%). Based on our results, P. leucophracta may be utilized as a natural source of antioxidant compounds in food and pharmaceutical areas.en_US
dc.description.sponsorshipScientific Research Council of Suleyman Demirel University, Isparta-Turkey [4631 - YL1-16]en_US
dc.description.sponsorshipThe authors would like to thank to Scientific Research Council of Suleyman Demirel University, Isparta-Turkey for the financial support (Project Number: 4631 - YL1-16).en_US
dc.identifier.citationSarıkürkçü, C., Cengiz, M., Küçükyumru, A., Zengin, G. (2018). Determination of Antioxidant Activities of Solvent Extracts From an Endemic Plant: Phlomis Leucophracta. Marmara Pharmaceutical Journal, 22(1), 86-90.
dc.identifier.doi10.12991/mpj.2018.45en_US
dc.identifier.endpage90en_US
dc.identifier.issn1309-0801en_US
dc.identifier.issue1en_US
dc.identifier.pmid#YOKen_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage86en_US
dc.identifier.urihttps://dx.doi.org/10.12991/mpj.2018.45
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36471
dc.identifier.volume22en_US
dc.identifier.wosWOS:000432474800011en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorZengin, Gökhan
dc.language.isoenen_US
dc.publisherMARMARA UNIV, FAC PHARMACYen_US
dc.relation.ispartofMarmara Pharmaceutical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPhlomis leucophractaen_US
dc.subjectphenolicsen_US
dc.subjectDPPHen_US
dc.subjectantioxidant activityen_US
dc.subjectreducing poweren_US
dc.titleDetermination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophractaen_US
dc.typeArticleen_US

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