Effects of vitamin E and prednisolone on biochemical and haematological parameters in endotoxaemic New Zealand white rabbits

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dc.contributor.authorYazar, E
dc.contributor.authorCol, R
dc.contributor.authorKonyalioglu, S
dc.contributor.authorBirdane, YO
dc.contributor.authorElmas, M
dc.contributor.authorBas, AL
dc.date.accessioned2020-03-26T16:48:31Z
dc.date.available2020-03-26T16:48:31Z
dc.date.issued2004
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractEffects of prednisolone and vitamin E on biochemical and haematological values were investigated in endotoxaemic rabbits. Forty rabbits were used and divided into four equal groups. Group I served as the control group; group 2 was infused with lipopolysaccharide (LPS) for 6 h; group 3 was injected with prednisolone before LPS administration; group 4 was injected with vitamin E for 4 consecutive days before LPS administration. Serum and blood samples were collected 8 h after the onset of LPS injection. Serum myoglobin, alanine aminotransferase, gamma glutamyl transferase, amylase, total bilirubin, direct bilirubin, creatinine, blood urea nitrogen, albumin, globulin, total protein, cholesterol, total lipids, triglycerides, low density lipoprotein, very low density lipoprotein, sodium, potassium and magnesium contents were measured. Red blood cell, white blood cell, platelet counts and percentage of differential leukocyte values were determined. It was found that prednisolone and vitamin E had a protective effect in endotoxaemic shock. Prednisolone was more effective in endotoxaemia than vitamin E.en_US
dc.identifier.endpage108en_US
dc.identifier.issn0042-4870en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage105en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19046
dc.identifier.volume48en_US
dc.identifier.wosWOS:000222417400005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNATL VETERINARY RESEARCH INSTen_US
dc.relation.ispartofBULLETIN OF THE VETERINARY INSTITUTE IN PULAWYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectrabbitsen_US
dc.subjectlipopolysaccharideen_US
dc.subjectprednisoloneen_US
dc.subjectvitamin Een_US
dc.subjectbiochemical valuesen_US
dc.subjecthaematological valuesen_US
dc.titleEffects of vitamin E and prednisolone on biochemical and haematological parameters in endotoxaemic New Zealand white rabbitsen_US
dc.typeArticleen_US

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