Mastitisli Süt İnerlerinden İzole Edilen Stafilokokların ß-Laktamaz Aktiviteleri ve Antibiyotiklere Duyalılıkları
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Dosyalar
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada, mastitisli süt ineklerinden izole edilen 82 koagulaz pozitif (78 Staphylococcus aureus, 4 S. in-termedius) ve 25 koagulaz negatif (15 S. epidermidis, 4 S. simulans, 2 S. chromogenes, 2 S. sapmphyticus, 2 S. caprae) toplam 107 stafilokok suşunun \beta -laktamaz aktiviteleri ve antibiyotiklere duyarlılıkları belirlendi. Koagulaz pozitif sta-filokoklardan 36'sı (% 46.1) (S. aureus) ve koagulaz negatif suşların 12'si (% 48) (10 S. epidermidis, 2 S. simulans) \beta -laktamaz pozitif bulundu. Antibiyotik duyarlılık testlerine göre; 107 stafilokok suşunun 105'i (% 98.1) enrofloksasilin'e, da-nofloksasilin'e, amoksisilin klavulonik asit'e, 104'ü (% 97.1) sefaperazonsulbaktam'a, 98'i (% 91.5) kloksasilin'e, 93'ü (% 86.9) sefaperazon'a, 86'sı (% 80.3) oksasilin'e, 85'i (% 79.4) oksitetrasiklin'e, 83'ü (% 77.5) ampisilinsulbaktam'a, 80'i (% 74,7) gentamisin'e ve 76'sı (% 71.0) trimetoprim şulfametaksazol'a duyarlı bulundu. Ayrıca, stafilokok suşlarının 67'si (% 62.3) ampisilin'e, 66'sı (% 61.7) penisilin'e, 50'si (% 46.8) eritromisin'e, 42'si (% 39.3) amoksisiline dirençli olduğu tespit edildi.
\ß -lactamase activity and susceptibility to antibiotics of Staphylococci isolated from milk samples of mastitic dairy cows were determined in this study. A total of 107 Staphylococci which consisted of 82 coagulase positive (Staphylococcus aureus 76, S. intermedius 4) and 25 coagulase negative (S. epidermidis 15, S. simulans 4, S. chromogenes 2, S. saprophyticus 2, S. caprae 2) was used. Of coagulase positive strains, 36 (46.1 %) which all were identified, as S. aureus and 12 (48 %) of the coagulase negative strains (S. epidermidis 10 and S. simulans 2) were found to have \beta -lactamase activity. Antibiotic susceptibility tests revealed that 105 (98.1 %) of 107 Staphylococci strains were found susceptible to either enroflaxacin or danofloxacin or amoxicillinclavuculanic acid. Susceptibility test results for other antibacterial agents with the 107 strains were as follows: 104 (97.1 %) for the sefaperazonesulbactam; 98 (91.5 %) clo-xacilline; 93 (86.9 %) sefaperazone; 86 (80.3 %) oxacilline; 85 (79.4 %); oxytetracycline; 83 (77.5 %); ampicillinesulbactam; 80 (74.7 %) gentamycin; 76 (71.0 %) trimetoprimsulfametaksazol. Of the 107 strains 67 (62.3 %) were found to resistant to ampicillin while 66 (61.7 %), 50 (46.8 %) and 42 (39.3%) were also found to have susceptibility to penicillin, eritromycin and amoxicillin, respectively.
\ß -lactamase activity and susceptibility to antibiotics of Staphylococci isolated from milk samples of mastitic dairy cows were determined in this study. A total of 107 Staphylococci which consisted of 82 coagulase positive (Staphylococcus aureus 76, S. intermedius 4) and 25 coagulase negative (S. epidermidis 15, S. simulans 4, S. chromogenes 2, S. saprophyticus 2, S. caprae 2) was used. Of coagulase positive strains, 36 (46.1 %) which all were identified, as S. aureus and 12 (48 %) of the coagulase negative strains (S. epidermidis 10 and S. simulans 2) were found to have \beta -lactamase activity. Antibiotic susceptibility tests revealed that 105 (98.1 %) of 107 Staphylococci strains were found susceptible to either enroflaxacin or danofloxacin or amoxicillinclavuculanic acid. Susceptibility test results for other antibacterial agents with the 107 strains were as follows: 104 (97.1 %) for the sefaperazonesulbactam; 98 (91.5 %) clo-xacilline; 93 (86.9 %) sefaperazone; 86 (80.3 %) oxacilline; 85 (79.4 %); oxytetracycline; 83 (77.5 %); ampicillinesulbactam; 80 (74.7 %) gentamycin; 76 (71.0 %) trimetoprimsulfametaksazol. Of the 107 strains 67 (62.3 %) were found to resistant to ampicillin while 66 (61.7 %), 50 (46.8 %) and 42 (39.3%) were also found to have susceptibility to penicillin, eritromycin and amoxicillin, respectively.
Açıklama
Anahtar Kelimeler
Staphylococcus aureus, P-Laklamaz, Antibiyotik Duyarlılık, B-Lactamase, Antibiotic Susceptibility
Kaynak
Veteriner Bilimleri Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
17
Sayı
4
Künye
Hadimli, H. H., Ateş, M., Güler, L., Kav, K., Öncel, T., (2001). Mastitisli Süt İnerlerinden İzole Edilen Stafilokokların ß-Laktamaz Aktiviteleri ve Antibiyotiklere Duyalılıkları. Veteriner Bilimleri Dergisi, 17(4), 21-25.
