CHARACTERIZATION OF UROPATHOGENIC ESCHERICHIA COLI STRAINS: ANTIBIOTIC RESISTANCE PATTERNS, DETECTION OF ESBL GENES AND INTERACTIONS BY LYTIC PHAGES

Basit Öğe Kaydı
dc.contributor.authorUysal, Ahmet
dc.contributor.authorGunes, Erdogan
dc.contributor.authorArslan, Emine
dc.contributor.authorDurak, Yusuf
dc.date.accessioned2020-03-26T19:53:03Z
dc.date.available2020-03-26T19:53:03Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study, 97 Escherichia coli strains isolated from urinary tract infections were evaluated in terms of phenotypic diversity, susceptibility to sixteen antibiotics, and extended spectrum of beta lactamase (ESBL) characteristics. The bacteriophage interactions was used to identify the relations of the E.coli isolates. Results showed that 21 of the 76 typable strains revealed 19 different phage types. Phage types of 21 strains could not be determined. Antibiotic susceptibility tests, performed against sixteen antibiotics, showed that although the isolates revealed 44 different types of resistance profiles, the strains showed the greatest resistance to cephalothin (54.6%), followed by tetracycline (53.6%), nalidixic acid (44.3%), and aztreonam and ofloxacin (29.8%). There was no resistance to amikacin and meropenem, and all strains were susceptible to meropenem. ESBL detection conducted by double disc synergy and multiplex polymerase chain reaction methods showed that 13 of 97 (13.4%) strains were ESBL-producing. Of the 13 ESBL-producing isolates, two carried bla(CTX-M), six bla(TEM), five bla(OXA), and one bla(TEM) and bla(SHV) at same time. We concluded that lytic phages could not be successful for typing the strains phenotypically. The monitoring of antimicrobial resistance levels and antimicrobial usage in humans should be an integral part of the prevention and control of antimicrobial resistance.en_US
dc.identifier.endpage414en_US
dc.identifier.issn1018-4619en_US
dc.identifier.issn1610-2304en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage402en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36389
dc.identifier.volume27en_US
dc.identifier.wosWOS:000426337900050en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherPARLAR SCIENTIFIC PUBLICATIONS (P S P)en_US
dc.relation.ispartofFRESENIUS ENVIRONMENTAL BULLETINen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectUropathogenic E. colien_US
dc.subjectphage typingen_US
dc.subjectantibiotic resistanceen_US
dc.subjectESBL genesen_US
dc.subjectmultiplex PCRen_US
dc.titleCHARACTERIZATION OF UROPATHOGENIC ESCHERICHIA COLI STRAINS: ANTIBIOTIC RESISTANCE PATTERNS, DETECTION OF ESBL GENES AND INTERACTIONS BY LYTIC PHAGESen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu