Phenolic Compounds, Antioxidant Properties and Enzyme Inhibition Ability of Adiantum capillus veneris L. linked to Alzheimer's Disease, Diabetes Mellitus and Skin Disorders

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dc.contributor.authorAbdulqadir, Ako
dc.contributor.authorÇakmak, Yavuz S.
dc.contributor.authorZengin, Gökhan
dc.date.accessioned2020-03-26T19:55:04Z
dc.date.available2020-03-26T19:55:04Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAdiantum capillus-veneris L. is one of the best ferns that are used in traditional medicine for breaking kidney stones. This study aimed to evaluate antioxidant activity of the different extracts of A. capillus-veneris using the phosphomolybdenum assay, free radical scavenging activity (DPPH), ferric reducing antioxidant power (FRAP), and cupric ion reducing power activity test (CUPRAC). Besides, the enzyme inhibition activities were determined against acetylcholinesterase, tyrosinase, alpha-glucosidase and alpha-amylase. Total and individual phenolic compounds were also determined by spectrophotometric and HPLC methods, respectively. Total phenolic and flavonoid contents were found to change between 354-441 mg GAE/g and 23-123 mg QE/g, respectively. The major phenolic compounds were benzoic acid, epicatechin, syringic acid and catechin. Methanol and ethyl acetate extracts exhibited stronger antioxidant abilities compared to water extract. A. capillus-veneris extracts showed high enzyme inhibition activities except for butrylcholinesterase. The results indicated that the different extracts of A. capillus-veneris L. can be used as natural sources of antioxidants and enzyme inhibitors.en_US
dc.identifier.doi10.2174/1385272822666180711145256en_US
dc.identifier.endpage1703en_US
dc.identifier.issn1385-2728en_US
dc.identifier.issn1875-5348en_US
dc.identifier.issue17en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1697en_US
dc.identifier.urihttps://dx.doi.org/10.2174/1385272822666180711145256
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36846
dc.identifier.volume22en_US
dc.identifier.wosWOS:000447281500005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherBENTHAM SCIENCE PUBL LTDen_US
dc.relation.ispartofCURRENT ORGANIC CHEMISTRYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAdiantum capillus-veneris L.en_US
dc.subjectbiological activitiesen_US
dc.subjectdiabetesen_US
dc.subjectAlzheimeren_US
dc.subjectskin disordersen_US
dc.subjectDiabetes Mellitusen_US
dc.titlePhenolic Compounds, Antioxidant Properties and Enzyme Inhibition Ability of Adiantum capillus veneris L. linked to Alzheimer's Disease, Diabetes Mellitus and Skin Disordersen_US
dc.typeArticleen_US

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