Activity of essential oils and individual components against acetyl and butyrylcholinesterase

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dc.contributor.authorOrhan, Ilkay
dc.contributor.authorKartal, Murat
dc.contributor.authorKan, Yueksel
dc.contributor.authorSener, Bilge
dc.date.accessioned2020-03-26T17:26:22Z
dc.date.available2020-03-26T17:26:22Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractWe have tested acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of nineteen essential oils obtained from cultivated plants, namely one from Anethum graveolens L. (organic fertilizer), two from Foeniculum vulgare Mill. collected at fully-mature and flowering stages (organic fertilizer), two from Melissa officinalis L. (cultivated using organic and chemical fertilizers), two from Mentha piperia L. and M. spicata L. (organic fertilizer), two from Lavandula officinalis Chaix ex Villars (Cultivated using organic and chemical fertilizers), two from Ocimum basilicum L. (green and purple-leaf varieties cultivated using only organic fertilizer), four from Origanum onites L., O. vulgare L., O. munitiflorum Hausskn., and O. majorana L. (cultivated using organic fertilizer), two from Salvia sclarea L. (organic and chemical fertilizers), one from S officinalis L. (organic fertilizer), and one from Satureja cuneifolia Ten. (organic fertilizer) by a spectrophotometric 1 mg/ml concentration. In addition, a method of Ellman using ELISA microplate-reader at 1 mg/ml number of single components widely encountered in most of the essential oils [gamma-terpinene, 4-allyl anisole, (-)-carvone, dihydrocarvone. (-)-phencone, cuminyl alcohol, cumol, 4-isopropyl benzaldehyde, trans-anethole, camphene, iso-borneol, (-)-borne0l, L-bornyl acetate. 2-decanol, 2-heptanol, methyl-heptanol, farnesol, nerol, iso-pulegol, 1,8-cineole, citral, citronellal, citronellol, geraniol, linalool, alpha-pinene, beta-pinene, piperitone, iso-menthone. menthofurane, linalyl oxide, linalyl ester, geranyl ester, carvacrol, thymol, menthol, vanilline, and eugenol] was also screened for the same activity in the same manner. Almost all of the essential oils showed a very high inhibitory activity (over 80%) against both enzymes, whereas the single components were not as active as the essential oils.en_US
dc.identifier.endpage553en_US
dc.identifier.issn0939-5075en_US
dc.identifier.issn1865-7125en_US
dc.identifier.issue07.08.2020en_US
dc.identifier.pmid18810999en_US
dc.identifier.startpage547en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22181
dc.identifier.volume63en_US
dc.identifier.wosWOS:000259106300013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWALTER DE GRUYTER GMBHen_US
dc.relation.ispartofZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectessential oilen_US
dc.subjectanticholinesteraseen_US
dc.subjectmonoterpenesen_US
dc.subjectAlzheimer's diseaseen_US
dc.titleActivity of essential oils and individual components against acetyl and butyrylcholinesteraseen_US
dc.typeArticleen_US

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