Predictive effect of preoperative anemia on long-term survival outcomes with non-muscle invasive bladder cancer

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dc.contributor.authorCelik O.
dc.contributor.authorAkand M.
dc.contributor.authorKeskin M.Z.
dc.contributor.authorEkin R.G.
dc.contributor.authorYoldas M.
dc.contributor.authorIlbey Y.O.
dc.date.accessioned2020-03-26T19:32:03Z
dc.date.available2020-03-26T19:32:03Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Anemia is the most common hematologic abnormality in bladder cancer (BC) patients. We evaluated the impact of preoperative anemia on oncologic outcomes in BC undergoing transurethral resection of a bladder tumor (TURBT) for the first time diagnosis. Materials and Methods: We retrospectively evaluated the data collected from 639 patients who underwent TURBT between January 2006 and September 2014 in our department. Of these patients, 320 qualified for inclusion in the study. The primary efficacy endpoint was the effect of preoperative anemia status on cancer-specific and overall survival. Independent t-test and chi-square analyses were performed to assess the effects of anemia on oncologic outcomes. Survival was estimated by using the Kaplan-Meier test. Results: There were 118 (36.9%) and 202 (63.1%) patients in the anemia (Group-1) and non-anemia groups (Group-2), respectively. The median follow-up duration was 68 months. Anemia was associated with decreased overall survival (p < 0.001). Comparison between cancer-specific survival of two groups did not show any statistically significant difference (p=0.17). Conclusions: Preoperative anemia status of BC patients according to World Health Organization classification is associated with decreased overall survival, but not with cancer-specific survival. We think that preoperative hemoglobin levels should be considered in patient counseling and decision-making for additional therapy.en_US
dc.identifier.doi10.7314/APJCP.2016.17.4.1755en_US
dc.identifier.endpage1758en_US
dc.identifier.issn1513-7368en_US
dc.identifier.issue4en_US
dc.identifier.pmid27221848en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1755en_US
dc.identifier.urihttps://dx.doi.org/10.7314/APJCP.2016.17.4.1755
dc.identifier.urihttps://hdl.handle.net/20.500.12395/34305
dc.identifier.volume17en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAsian Pacific Organization for Cancer Preventionen_US
dc.relation.ispartofAsian Pacific Journal of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAnemiaen_US
dc.subjectBladderen_US
dc.subjectHemoglobinen_US
dc.subjectSurvivalen_US
dc.subjectUrothelial carcinomaen_US
dc.titlePredictive effect of preoperative anemia on long-term survival outcomes with non-muscle invasive bladder canceren_US
dc.typeArticleen_US

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