Comparison of the Effects of Intravenous and Thoracic Epidural Patient-Controlled Analgesia With Morphine After Upper Abdominal Surgery

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dc.contributor.authorYosunkaya, Alper
dc.contributor.authorTavlan, Aybars
dc.contributor.authorTuncer, Sema
dc.contributor.authorReisli, Ruhiye
dc.contributor.authorTopal, Ahmet
dc.contributor.authorÖkesli, Selmin
dc.date.accessioned2020-03-26T16:45:31Z
dc.date.available2020-03-26T16:45:31Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractOur purpose was to compare the effects of patient-controlled analgesia (PCA) with intravenous (i.v.) and epidural morphine on pulmonary function and their analgesic efficacy and side effects after upper abdominal surgery. In a prospective study, patients were randomly allocated to receive either thoracic epidural (n = 20) or intravenous (n = 20) patient-controlled analgesia with morphine. Preoperatively and at 24 and 48 h after surgery, arterial blood-gas analysis, forced vital capacity (FVC), and forced expiratory volume in 1s (FEV1) were measured, and chest X-ray films were taken from all patients. Pain (at rest), morphine consumption, nausea and vomiting, pruritus, and respiratory rate were recorded during the first 48 postoperative hours. In this period, the amount of morphine that was used in the epidural PCA group (28.5 +/- 7.4 mg) was significantly lower than in the i.v. PCA group (49.4 +/- 27.0 mg). Pain scores were similar in the two groups. Throughout the study no differences were found in pH(a), PaCO2, PaO2, FVC or FEV1 between epidural and i.v. morphine groups. When compared with preoperative data, at 24 and 48 h after surgery, FVC, FEV1, and PaO2 decreased significantly in both groups (p < 0.05). Except pruritus, incidence of side effects occurred similarly in the two groups. In this study, we found no difference between the effects of epidural and i.v. administration of morphine with PCA on pulmonary function and analgesic efficacy.en_US
dc.identifier.citationYosunkaya, A., Tavlan, A., Tuncer, S., Reisli, R., Topal, A., Ökesli, S., (2003). Comparison of the Effects of Intravenous and Thoracic Epidural Patient-Controlled Analgesia With Morphine After Upper Abdominal Surgery. Pain Clinic, 15(3), 271-279. Doi: 10.1163/156856903767650790
dc.identifier.doi10.1163/156856903767650790en_US
dc.identifier.endpage279en_US
dc.identifier.issn0169-1112en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage271en_US
dc.identifier.urihttps://dx.doi.org/10.1163/156856903767650790
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18401
dc.identifier.volume15en_US
dc.identifier.wosWOS:000185739800010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorYosunkaya, Alper
dc.institutionauthorTavlan, Aybars
dc.institutionauthorTuncer, Sema
dc.institutionauthorReisli, Ruhiye
dc.institutionauthorTopal, Ahmet
dc.institutionauthorÖkesli, Selmin
dc.language.isoenen_US
dc.publisherVSP Bven_US
dc.relation.ispartofPain Clinicen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPostoperative Analgesiaen_US
dc.subjectPatient-Controlled Analgesiaen_US
dc.subjectOpioidsen_US
dc.subjectMorphineen_US
dc.subjectEpidural Anesthetic Techniquesen_US
dc.titleComparison of the Effects of Intravenous and Thoracic Epidural Patient-Controlled Analgesia With Morphine After Upper Abdominal Surgeryen_US
dc.typeArticleen_US

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