Calixarenes in Lipase Biocatalysis and Cancer Therapy

Basit Öğe Kaydı
dc.contributor.authorKarakurt, Serdar
dc.contributor.authorKellici, Tahsin F.
dc.contributor.authorMavromoustakos, Thomas
dc.contributor.authorTzakos, Andreas G.
dc.contributor.authorYilmaz, Mustafa
dc.date.accessioned2020-03-26T19:23:15Z
dc.date.available2020-03-26T19:23:15Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractCalixarenes are supramolecular structures characterized by their "calix" shape and their easy synthetic accessibility. They are amphiphilic in nature, thus they can bear in their structure both hydrophobic and hydrophilic features as well as charged groups. They are characterized by architectural plasticity responsible for their unique fine-tuned properties that can be shaped for an array of applications. Herein, we will focus, on their diverse available applications, and give special emphasis on biocatalysis and cancer therapy as two modern directions and emerging fields of interest that have been sporadically explored in the literature and can pave the way for the discovery of novel therapeutics. This review provides the first exhaustive examination on the enhanced catalytic activity and selectivity of calixarene-based encapsulated biocatalysts towards the synthesis of bioactive molecules. The application of functionalized calixarenes in cancer therapy is also analyzed towards the spatiotemporal control they can offer in targeted drug delivery.en_US
dc.description.sponsorshipScientific and Technical Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [111T027, 113Z445]; Research Foundation of Selcuk University (BAP)Selcuk University; European Union (European Regional Development Fund - ETPA); Greek national funds through the Operational Programme "Competitiveness and Entrepreneurship" (OPCE II)", "Joint Research and Technology programmes Bilateral Greece-Turkey"en_US
dc.description.sponsorshipWe would like to thank the Scientific and Technical Research Council of Turkey (TUBITAK-Grant Number 111T027 and 113Z445) and the Research Foundation of Selcuk University (BAP) for financial support of this work. This research has been co-financed by the European Union (European Regional Development Fund - ETPA) and Greek national funds through the Operational Programme "Competitiveness and Entrepreneurship" (OPCE II)", "Joint Research and Technology programmes Bilateral Greece-Turkey 2013- 2014"en_US
dc.identifier.doi10.2174/1385272820666151211192249en_US
dc.identifier.endpage1057en_US
dc.identifier.issn1385-2728en_US
dc.identifier.issn1875-5348en_US
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1043en_US
dc.identifier.urihttps://dx.doi.org/10.2174/1385272820666151211192249
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33326
dc.identifier.volume20en_US
dc.identifier.wosWOS:000372074400001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherBENTHAM SCIENCE PUBL LTDen_US
dc.relation.ispartofCURRENT ORGANIC CHEMISTRYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCalixarenesen_US
dc.subjectnanoparticlesen_US
dc.subjectenzyme immobilizationen_US
dc.subjectbiocatalystsen_US
dc.subjectcancer therapyen_US
dc.subjecttherapeuticsen_US
dc.titleCalixarenes in Lipase Biocatalysis and Cancer Therapyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu