The effects of gender and exercise on malondialdehyde, nitric oxide and total glutathione levels in rat liver

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dc.contributor.authorPepe, Hamdi
dc.date.accessioned2020-03-26T18:16:50Z
dc.date.available2020-03-26T18:16:50Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study examined the effects of gender, acute exhaustive exercise and endurance training on the levels of malondialdehyde (MDA), nitric oxide (NOx) and total glutathione (GSH) in rat liver. The study was carried out with 12-week-old male and female Wistar rats. Rats were randomly divided into four subgroups: untrained-control, trained-control, untrained-exhausted, and trained-exhausted. Endurance training consisted of swimming 1 h each day, 5 days a week, for 8 weeks. Rats in exhausted exercise group were forced to swim until exhaustion. Levels of MDA and GSH in the liver were affected by both gender and acute exhaustive exercise. There were no significant interactions between gender, acute exhaustive exercise and endurance training on MDA, NOx or GSH levels in rat liver. In contrast to MDA and GSH levels, the level of NOx was not affected by acute exhaustive exercise or gender. Acute exhaustive exercise increased lipid peroxidation in the liver, especially in females. As a result, we conclude that gender, exhaustive exercise and endurance training do not have an effect on liver MDA, NOx and GSH levels.en_US
dc.description.sponsorshipSelcuk University (S.U.-BAP, Konya, Turkey)Selcuk University [09401080]en_US
dc.description.sponsorshipI would like to thank Dr. Sevin Guney for assistance with data collection and Dr. Cigdem Ozer and his laboratory at Gazi University, Faculty of Medicine, Department of Physiology for their help with the biochemical assays used in this study. This study was supported by the Selcuk University Scientific Research Projects Coordinatorship (S.U.-BAP, Konya, Turkey), (Project no: 09401080).en_US
dc.identifier.doi10.5897/AJPP11.161en_US
dc.identifier.endpage521en_US
dc.identifier.issn1996-0816en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage515en_US
dc.identifier.urihttps://dx.doi.org/10.5897/AJPP11.161
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26935
dc.identifier.volume5en_US
dc.identifier.wosWOS:000295797700009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherACADEMIC JOURNALSen_US
dc.relation.ispartofAFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectOxidative stressen_US
dc.subjectacute exerciseen_US
dc.subjectexercise-trainingen_US
dc.subjectgenderen_US
dc.subjectliveren_US
dc.titleThe effects of gender and exercise on malondialdehyde, nitric oxide and total glutathione levels in rat liveren_US
dc.typeArticleen_US

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