Investigation of Methicillin Resistance of Staphylococcus aureus Strains Isolated from Various Sources by Different Methods

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dc.contributor.authorGunes, Erdogan
dc.contributor.authorDurak, Yusuf
dc.date.accessioned2020-03-26T18:42:15Z
dc.date.available2020-03-26T18:42:15Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObject of this study is to determine methicillin resistance of 150 strains of Staphylococcus aureus isolated and identified from various sources by the methods of oxacillin agar screen, broth microdilution and oxacillin disc diffusion, to compare sensitivity and specificity of these methods by making oxacillin agar screen test reference and to determine multi-antibiotic resistance in these strains. 16 (10.7%) of the 150 strains were determined as Methicillin-Resistant S.aureus (MRSA) through the methods of agar screen and microdilution while 17 (11.3%) strains were found as the same through the method of disc diffusion. Agar screen and microdilution methods were found as 100% compatible with each other. Sensitivity of the disc diffusion method was calculated as 100% while its specificity was calculated as 99.2%. Antibiotic susceptibility tests conducted by using the disc diffusion method against 10 antibiotics showed that the highest resistances of MRSA and MSSA (Methicillin-Susceptible S. aureus) strains were determined as 100% and 93.3% to penicillin, 81.2% and 5.2% to tetracycline, 62.5% and 1.5% to ofloxacin, 56.2% and 0.7% to rifampin respectively while all strains were found susceptible to linezolid and vancomycin. It was seen that multiple-antibiotic resistance in MRSA strains are higher compared with that in MSSA strains. It has been thought that linezolid may be an alternative for vancomycin in curing MRSA infections.en_US
dc.description.sponsorshipSelcuk University Scientific Research Projects Coordinating Office (BAP)Selcuk University [10101023]en_US
dc.description.sponsorshipWe would like to Selcuk University Scientific Research Projects Coordinating Office (BAP) for supporting this project financially (project No. 10101023).en_US
dc.identifier.endpage2823en_US
dc.identifier.issn0973-7510en_US
dc.identifier.issn2581-690Xen_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage2815en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29587
dc.identifier.volume7en_US
dc.identifier.wosWOS:000331428900040en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDR M N KHANen_US
dc.relation.ispartofJOURNAL OF PURE AND APPLIED MICROBIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectOxacillin agar screenen_US
dc.subjectantibiotic resistanceen_US
dc.subjectMethicillin resistanceen_US
dc.subjectStaphylococcus aureusen_US
dc.titleInvestigation of Methicillin Resistance of Staphylococcus aureus Strains Isolated from Various Sources by Different Methodsen_US
dc.typeArticleen_US

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