The association of peritoneal transport properties with 24-hour blood pressure levels in CARP patients

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dc.contributor.authorTonbul, Halil Zeki
dc.contributor.authorAltıntepe, Lütfullah
dc.contributor.authorSözlü, Çetin
dc.contributor.authorYeksan, Mehdi
dc.contributor.authorYıldız, Alaattin
dc.contributor.authorTürk, Süleyman
dc.date.accessioned2020-03-26T16:46:40Z
dc.date.available2020-03-26T16:46:40Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: We aimed to investigate the effects of peritoneal transport characteristics on blood pressure (BP) parameters, measured by 24-hour ambulatory blood pressure monitoring (ABPM), and on the development of left ventricular hypertrophy (LVH) in continuous ambulatory peritoneal dialysis (CAPD) patients. Design: Cross-sectional and prospective design. Setting: Tertiary-care center. Patients: 25 CAPD patients (11 male, 14 female; mean age 47 ± 14 years) were included. Mean time on CAPD was 22.9 ± 18 months and all patients had been dialyzed for more than 6 months. The patients were divided into high, high-average, low-average, and low transport groups according to peritoneal equilibration test results. Main Outcome Measures: Daytime and nighttime systolic and diastolic BP and left ventricular mass index among the different peritoneal transport groups; changes in BP parameters before and after increase in ultrafiltration. Results: On 24-hour ABPM records, 13 patients (52%) were found to be hypertensive. Both mean systolic and diastolic BP were significantly increased in high-transporter groups compared to low transporters in both daytime and nighttime BP parameters. Left ventricular mass index was higher in high transporters compared to low transporters, without reaching statistical significance: 160 ± 23 vs 119 ± 41 g/m2, p > 0.05. Following increase in ultrafiltration, mean systolic (145 ± 13 vs 128 ± 5 mmHg, p < 0.001) and diastolic (96 ± 10 vs 81 ± 3 mmHg, p < 0.001) BP decreased, and BP levels returned to normotensive levels in 6 (46%) of the 13 hypertensive patients, requiring discontinuation of antihypertensive drugs. Conclusion: Improvement in volume status resulted in a decrease in both daytime and nighttime BP. Differences in peritoneal transport properties were associated with the development of hypertension and LVH.en_US
dc.identifier.endpage52en_US
dc.identifier.issn0896-8608en_US
dc.identifier.issue1en_US
dc.identifier.pmid12691506en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage46en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18708
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofPeritoneal Dialysis Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHypertensionen_US
dc.subjectLeft ventricular hypertrophyen_US
dc.subjectPeritoneal transporten_US
dc.subjectPETen_US
dc.titleThe association of peritoneal transport properties with 24-hour blood pressure levels in CARP patientsen_US
dc.typeArticleen_US

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