Dose rate definition in brachytherapy

dc.authorid0000-0001-9481-6307
dc.contributor.authorYavaş, Güler.
dc.date.accessioned2020-03-26T20:13:30Z
dc.date.available2020-03-26T20:13:30Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBrachytherapy (BRT) is defined as treatment from a short distance. The word is derived from the word "brachy" that means "short" in Greek. Treatment in BRT is performed by placing the radioactive source in or near the tumor tissue. According to the report 38 of the International Commission on Radiation Units and Measurements (ICRU 38), BRI is divided into three types according to the activity of the radioactive source. Low-dose rate (LDR) implants deliver dose at the rate of 0.4-2 Gy/h, requiring treatment times of 24-144 11. LDR BRT has extensive experience with well-known efficacy and side effects. Medium-dose rate (MDR) BRT, defined as the 2-12 Gy/h range, is rarely used. High-dose rate (HDR) BRT uses dose rates in excess of 0.2 Gy/min (12 Gy/h). Although not defined in ICRU 38, there is also a very-low dose (ultra LDR: ultra-low dose rate (ULDR)) BRT of 0.01-0.3 Gy/h. Pulse dose rate (PDR) BRT is a new BRT concept that is also not defined in ICRU 38. PDR BRT combines physical advantages of LDR BRT technology with the radiobiological advantages of LDR BRT. Each dose rate in the clinic has its advantages and disadvantages. It is difficult to compare the efficacy of dose rates in the clinic because of the lack of prospective randomized studies comparing the defined dose rates with each other. In this review, we aimed to explain the advantages, disadvantages, and common clinical sites of use of different dose rates.en_US
dc.identifier.citationYavaş, G. (2019). Dose Rate Definition in Brachytherapy. Turkish Journal of Oncology, 34(1), 44-55.
dc.identifier.doi10.5505/tjo.2019.1924en_US
dc.identifier.endpage55en_US
dc.identifier.issn1300-7467en_US
dc.identifier.pmid#YOKen_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage44en_US
dc.identifier.urihttps://dx.doi.org/10.5505/tjo.2019.1924
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37707
dc.identifier.volume34en_US
dc.identifier.wosWOS:000483634700009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorYavaş, Güler.
dc.language.isoenen_US
dc.publisherKARE PUBLen_US
dc.relation.ispartofTURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGYen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBrachytherapyen_US
dc.subjecthigh-dose rateen_US
dc.subjectlow-dose rateen_US
dc.subjectmedium-dose rateen_US
dc.subjectpulse dose rateen_US
dc.subjectultra-low dose rateen_US
dc.titleDose rate definition in brachytherapyen_US
dc.typeArticleen_US

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