Chiral Calix[4]arenes-Bearing Prolinamide Functionality as Organocatalyst for Asymmetric Direct Aldol Reactions in Water
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
TAYLOR & FRANCIS LTD
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The chiral calix[4]arene derivative (6) bearing an L-prolinamido group has been designed and proved to be a water compatible efficient organocatalysts for a direct enantioselective aldol reaction. Compound 6 catalyzes the aldol reaction of cyclohexanone and a variety of aromatic aldehydes yielding anti-aldol products in high yield with enantioselectivities of up to 93% and diastereoselectivity of up to 95:5.
Açıklama
Anahtar Kelimeler
Aldol, calix[4]arene, enantioselectivity, organocatalysis, proline
Kaynak
POLYCYCLIC AROMATIC COMPOUNDS
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
38
Sayı
2
