Importance of the cell block technique in diagnosing patients with non-small cell carcinoma accompanied by pleural effusion

Basit Öğe Kaydı
dc.contributor.authorUgurluoglu C.
dc.contributor.authorKurtipek E.
dc.contributor.authorUnlu Y.
dc.contributor.authorEsme H.
dc.contributor.authorDuzgun N.
dc.date.accessioned2020-03-26T19:08:21Z
dc.date.available2020-03-26T19:08:21Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Cytological examination of pleural effusions is very important in the diagnosis of malignant lesions. Thoracentesis is the first investigation to be performed in a patient with pleural effusion. In this study, we aimed to compare traditional with cell block methods for diagnosis of lung disease accompanied by pleural effusion. Materials and Methods: A total of 194 patients with exudative pleural effusions were included. Ten mililiters of fresh pleural fluid were obtained by thoracentesis from all patients in the initial evaluation. The samples gathered were divided to two equal parts, one for conventional cytological analysis and the other for analysis with the cell block technique. In cytology, using conventional diagnostic criteria cases were divided into 3 categories, benign, malignant and undetermined. The cell block sections were evaluated for the presence of single tumor cells, papillary or acinar patterns and staining with mucicarmine. In the cell block examination, in cases with sufficient cell counts histopathological diagnosis was performed. Results: Of the total undergoing conventional cytological analyses, 154 (79.4%)were reported as benign, 33 (17%) as malignant and 7 (3.6%) as suspicious of malignancy. With the cell block method the results were 147 (75.8%) benign, 12 (6.2%) metastatic, 4 (2.1%) squamous cell carcinoma, 18 (9.3%) adenocarcinoma, 5 (2.6%) large cell carcinoma, 2 (1%) mesothelioma, 3 (1.5%) small cell carcinoma, and 3 (1.5%) lymphoma. Conclusions: Our study confirmed that the cell block method increases the diagnostic yield with exudative pleural effusions accompanying lung cancer.en_US
dc.identifier.doi10.7314/APJCP.2015.16.7.3057en_US
dc.identifier.endpage3060en_US
dc.identifier.issn1513-7368en_US
dc.identifier.issue7en_US
dc.identifier.pmid25854405en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage3057en_US
dc.identifier.urihttps://dx.doi.org/10.7314/APJCP.2015.16.7.3057
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32828
dc.identifier.volume16en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAsian Pacific Organization for Cancer Preventionen_US
dc.relation.ispartofAsian Pacific Journal of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCell blocken_US
dc.subjectImmünohystochemistryen_US
dc.subjectNon-small cell lung canceren_US
dc.subjectPleural effusionen_US
dc.titleImportance of the cell block technique in diagnosing patients with non-small cell carcinoma accompanied by pleural effusionen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu