A Comperative Study on Allergic Reactions Related to Various Anaesthetic Agents
Küçük Resim Yok
Tarih
1997
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This study was designed to determine and compare allergic reactions due to IV anaesthetic agents used during surgical operations. From the Departments of general surgery, urology and orthopaedics 60 adults patients (27 male and 33 female with 35.9±12.5 mean age) having no tumoral-endocrine pathology or allergy/athopy history and being classified as ASA I and II were included to the study. They were divided into four groups as equal in number. The groups were similar demographically. After permission of the hospital's ethic comittee, the 4 groups were respectively infused with propofol (2.5 mg/kg) thiopentone (5 mg/kg), etomidate (0.3 mg/kg) and midazolam (0.3 mg/kg) for induction. Serum IgE levels (by ELISA using EIA-Bioclone, Australia) and eosinophil and basophil counts (by using autoanalyser) were measured in blood samples drawn both just before, after induction and 24 hrs later. As a result, we detected thiopentone to cause significant increase in serum IgE levels and eosinophil and basophil counts more than those of the other 3 agents (p<0.05). We concluded that, instead of using thiopentone, propofol, etomidate or midazolam may be a safer alternative for patients with an allergy/athopy history.
Açıklama
Anahtar Kelimeler
Allergic reactions, Etomidate, IgE, Midazolam, Propofol, Thiopentone
Kaynak
Turk Anesteziyoloji ve Reanimasyon
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
25
Sayı
8
Künye
Altındiş, M., Tuncer, S., Özmen, S., Ökeşli, S., Sütçü, A., Baysal, B., (1997). A Comperative Study on Allergic Reactions Related to Various Anaesthetic Agents. Turk Anesteziyoloji ve Reanimasyon, 25(8), 352-355.
