Evaluation of the Repair of Full-thickness Articular Cartilage Defects Filled With Autologous Exogenous Fibrin Clot: an Experimental Study in the Shoulder Joint of Dogs

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Tarih

2003

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

De Gruyter Poland Sp Zoo

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

To determine whether the optimizing effect of an exogenous fibrin clot in the repair of full-thickness articular cartilage defects is valid when joint motions are restricted, standard osteochondral defects were constituted in the articular surface of the humeral head in 16 adult dogs. The defects in 8 dogs were packed with fibrin clots that had been prepared exogenously from each animal and the defects of the other animals were left empty The operated limbs were inactivated for 2 weeks postoperatively and the healing response was then examined using routine histology at 2, 4, 8 and 12-week intervals. Although the clot-filled and control (empty) defects initially healed through proliferation of fibrous connective tissue; the clot-filled defects finally modulated into fibrocartilage with completed subchondral bone formation. The clot-filled defects demonstrated a more advanced reparative tissue which was congruent with the intact articular surface from 4 weeks after the intervention.

Açıklama

Anahtar Kelimeler

Articular cartilage, Dog, Exogenous fibrin, Healing

Kaynak

Acta Veterinaria-Beograd

WoS Q Değeri

Q4

Scopus Q Değeri

Cilt

53

Sayı

4

Künye

Avkı, S., İzci, C., (2003). Evaluation of the Repair of Full-thickness Articular Cartilage Defects Filled With Autologous Exogenous Fibrin Clot: an Experimental Study in the Shoulder Joint of Dogs. Acta Veterinaria-Beograd, 53(4), 259-268. Doi: 10.2298/AVB0304259A