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Öğe A 1- to 12-year clinical evaluation of 106 endosseous implants supporting fixed and removable prostheses(QUINTESSENCE PUBLISHING CO INC, 2007) Aykent, Filiz; İnan, Özgür; Özyeşil, Atilla Gökhan; Alptekin, Nilgün ÖzlemThe purpose of this article is to report on the long-term clinical evaluation of patients treated with dental implants. A total of 106 implants were placed in 34 patients and restored with fixed partial dentures and overdentures. The 12-year cumulative implant survival and success rates were 95.2% and 90.2%, respective Probing depths around mandibular implants were significantly lower than those around maxillary implants (P <.05). The cumulative implant success rate in nonsmokers was 97.7%, but this dropped to 75.81 % in smokers. Also, patients rehabilitated with implant-supported overdentures had more peri-implant tissue inflammation than patients with fixed prostheses.Öğe Alternative prosthodontic rehabilitation of traumatic patients with tooth, bone and soft tissue loss: Two clinical reports(2018) Özel, Gülsüm Sayın; İnan, Özgür; Dolanmaz, DoğanAcquired defects typically result from traumatic injuries such as falls, motor vehicle accidents, gunshot injuries or radiation injuries. Those maxillofacial defects resulting from motor vehicle accidents in particular often involve various soft and hard-tissue injuries such as fractures or avulsions of the maxillary or mandibular teeth or fractures of the temporomandibular joints. For a patient suffering such injuries, the retention and stabilization of a prosthesis that contributes to the patient's physical and psychological well-being are often difficult to achieve due to the nature of the moveable tissue beds involved and the resulting lack of support from the remaining teeth and bones. This clinical report describes the treatments of two partially edentulous patients with traumatic injuries that resulted from motor vehicle accidents. The prosthetic rehabilitations were accomplished through the manufacture of (1) a mandibular prosthesis with an extracoronal bar attachment, and (2) a maxillary implant-supported removable prosthesis.Öğe Effect of anatomical location (mandible vs maxilla) of dental implants on the BMP-2, BMP-7, sRANKL and OPG levels in periimplant crevicular fluid during osseointegration. A pilot study(Selçuk Üniversitesi, 2019) Sağlam, Mehmet; Dolanmaz, Doğan; Koçak, Emrah; Gürsoytrak, Burcu; İnan, Özgür; Dündar, Niyazi; Hakkı, Sema S.Background: The aim of this study was to investigate levels of bone morphogenetic protein-2 (BMP-2), BMP-7, soluble receptor activator of nuclear factor-kB ligand (sRANKL) and osteoprotegerin (OPG) in the peri-implant crevicular fluid (PICF) of implants placed in both maxilla and mandible during the osseointegration period. Materials and Methods: Thirty-three patients (17 females and 16 males; mean age 47.03±11.23 years) were included in this study. A total of 33 implants were placed in both of maxilla (Group 1/n=18) and mandible (group 2/n=15). Peri-implant crevicular fluid (PICF) samples, modified plaque index (MPI), gingival index (GI) and probing depth (PD) measurements were obtained at 1 and 3 months after surgery. PICF levels of BMP-2/-7, sRANKL and OPG were analyzed by ELISA. Results: No complications were observed during the healing period. No significant differences were observed in the PICF levels of sRANKL, OPG, BMP-2 and BMP-7 and evaluated clinical parameters between groups at any time point (p>0.05). While PICF volume of group 2 was greater than group 1 at first month, PICF volume of group 1 was greater than group 2 at 3 months (p<0.05). There was a positive correlation between sRANKL levels and PICF volume (p<0.05) and a strong correlation between BMP-2 and BMP-7 (p<0.01). Conclusion: The results of this pilot study didn’t show any significant difference in PICF levels of BMP-2, BMP-7, sRANKL, and OPG in terms of anatomic location of dental implants. Further welldesigned studies should be carried out to evaluate the relationship between bone related biomarkers and anatomic location of dental implants.Öğe The effect of different dentin hypersensitivity treatments on the shear bond strength of self-adhesive resin to dentin(Selçuk Üniversitesi, 2017) Akın, Ceyda; İnan, ÖzgürBackground:This in vitro study evaluated the shear bond strength of self adhesive resin cement to dentin with different dentin hypersensitivity treatments. Methods: Forty-eight dentin specimens were randomly divided into four groups (n=12). (1) Group C (control); (2) Group G (treated with Gluma Desensitizer); (3) Group E (treated with Er:YAG laser); (4) Group E+G (treated with Er:YAG laser following Gluma Desensitizer). Flowable self adhesive resin cement was applied to dentin surface and shear bond strength tests were performed. The mean SBS values were calculated and data were analyzed by one-way ANOVA test and Post Hoc test. Results:Statistical analysis revealed that Group E statistically significant lower bond strength values than the other desensitizing treatment groups tested (p<0.005). While there were no significant differences among the other groups (p>0.05). Conclusion:The shear bond strength of self-adhesive resin will be decrease if dentin surface is irradiated with Er:YAG laserÖğe The Effect of Thread Design on Stress Distribution in a Solid Screw Implant: A 3D Finite Element Analysis(SPRINGER HEIDELBERG, 2010) Eraslan, Oğuz; İnan, ÖzgürThe biomechanical behavior of implant thread plays an important role on stresses at implant-bone interface. Information about the effect of different thread profiles upon the bone stresses is limited. The purpose of this study was to evaluate the effects of different implant thread designs on stress distribution characteristics at supporting structures. In this study, three-dimensional (3D) finite element (FE) stress-analysis method was used. Four types of 3D mathematical models simulating four different thread-form configurations for a solid screw implant was prepared with supporting bone structure. V-thread (1), buttress (2), reverse buttress (3), and square thread designs were simulated. A 100-N static axial occlusal load was applied to occlusal surface of abutment to calculate the stress distributions. Solidworks/Cosmosworks structural analysis programs were used for FE modeling/analysis. The analysis of the von Mises stress values revealed that maximum stress concentrations were located at loading areas of implant abutments and cervical cortical bone regions for all models. Stress concentration at cortical bone (18.3 MPa) was higher than spongious bone (13.3 MPa), and concentration of first thread (18 MPa) was higher than other threads (13.3 MPa). It was seen that, while the von Mises stress distribution patterns at different implant thread models were similar, the concentration of compressive stresses were different. The present study showed that the use of different thread form designs did not affect the von Mises concentration at supporting bone structure. However, the compressive stress concentrations differ by various thread profiles.Öğe Effects of airborne-particle abrasion, sodium hydroxide anodization, and electrical discharge machining on porcelain adherence to cast commercially pure titanium(WILEY, 2007) Acar, Aslı; İnan, Özgür; Halkacı, SelçukThe aim of this study was to determine the effect of airborne-particle abrasion (APA), sodium hydroxide anodization (SHA), and electrical discharge machining (EDM) on cast titanium surfaces and titanium-porcelain adhesion. Ninety titanium specimens were cast with pure titanium and the alpha-case layer was removed. Specimens were randomly divided into three groups. Ten specimens from each group were subjected to APA. SHA was applied to the second subgroups, and the remaining specimens were subjected to the EDM. For the control group, 10 specimens were cast using NiCr alloy and subjected to only APA. Surfaces were examined by using scanning electron microscope and a surface profilometer. Three titanium porcelains were fused on the titanium surfaces, whereas NiCr specimens were covered with conventional porcelain. Titanium-porcelain adhesion was characterized by a 3-point bending test. Statistical analysis showed that the porcelain-metal bond strength of the control group was higher than that of the titanium-porcelain system (p < 0.05). There were no significant differences between the bond strengths of titanium groups (p > 0.05), except the bond strengths of Noritake Super Porcelain TI-22 groups on which APA and SHA were applied (p < 0.05). SHA and EDM as surface treatment did not improve titanium-porcelain adhesion when compared to APA. (c) 2006 Wiley Periodicals, Inc.Öğe Effects of Sandblasting and Electrical Discharge Machining on Porcelain Adherence to Cast and Machined Commercially Pure Titanium(Wiley-Liss, 2006) İnan, Özgür; Acar, Aslı; Halkacı, SelçukThe aim of this study was to determine the effect of sandblasting and electrical discharge machining (EDM) on cast and machined titanium surfaces and titanium-porcelain adhesion. Twenty machined titanium specimens were prepared by manufacturer (groups 1 and 2). Thirty specimens were prepared with autopolymerizing acrylic resin. Twenty of these specimens (groups 3 and 4) were cast with commercially pure titanium and the alpha-case layer was removed. For control group (group 5), 10 specimens were cast by using NiCr alloy. Groups 2 and 4 were subjected to EDM while groups 1, 3, and 5 were subjected to sandblasting. Surface examinations were made by using a scanning electron microscope (SEM). A low-fusing porcelain was fused on the titanium surfaces, whereas NiCr specimens were covered using a conventional porcelain. Titanium-porcelain adhesion was characterized by a 3-point bending test. Results were analyzed by Kruskal-Wallis and Mann-Whitney U tests. Metal-porcelain interfaces were characterized by SEM. The bond strength of control group was higher than that of the titanium-porcelain system. There was no significant difference between cast and machined titanium groups (p > 0.05). There was no significant difference between EDM and sandblasting processes (p > 0.05). The use of EDM as surface treatment did not improve titanium-porcelain adhesion compared with sandblasting.Öğe Evaluation of Marginal Fit of Two Allceramic Copings with Two Finish Lines(2012) Subaşı, Gülce; Öztürk, Nilgün; İnan, Özgür; Bozoğulları, NalanObjectives: This in-vitro study investigated the marginal fit of two all-ceramic copings with 2 finish line designs. Methods: Forty machined stainless steel molar die models with two different margin designs (chamfer and rounded shoulder) were prepared. A total of 40 standardized copings were fabricated and divided into 4 groups (n=10 for each finish line-coping material). Coping materials tested were IPS e.max Press and Zirkonzahn; luting agent was Variolink II. Marginal fit was evaluated after cementation with a stereomicroscope (Leica MZ16). Two-way analysis of variance and Tukey-HSD test were performed to assess the influence of each finish line design and ceramic type on the marginal fit of 2 all-ceramic copings (? =.05). Results: Two-way analysis of variance revealed no statistically significant differences for marginal fit relative to finish lines (P=.362) and ceramic types (P=.065). Conclusion: Within the limitations of this study, both types of all-ceramic copings demonstrated that the mean marginal fit was considered acceptable for clinical application (?120 ?m). (Eur J Dent 2012;6:163-168)Öğe Evaluation of Osteoblastic Activity Around Dental Implants Using Bone Scintigraphy(Wiley, 2010) Kalaycı, Abdullah; Durmuş, Ercan; Taştekin, Güngör; Işık, Kubilay; İnan, ÖzgürObjectives: The aim of this study was to evaluate the osteoblastic activity around delayloaded intraosseous dental implants using nuclear medicine imaging techniques. Material and methods: Seven totally edentulous patients (two females and five males, between 48 and 57 years of age) were included in the study. Two implants were inserted into mandibular canine regions and removable prostheses were produced after 3 months. Whole-body bone scintigraphies with 20 mCi technetium 99m labelled methylene diphosphonate were taken from the patients before implant insertion, 3 months after implant placement just before the prostheses were made and 1 year after implant placement. Standardized count/pixel (SC/P) rates were calculated for each patient. Preimplantation SC/P values were compared with the 3- and 12-month values. Three-month values were compared with the 12-month values as well. Results: SC/P rates in the third month were significantly higher (Po0.05) than preoperative values and the SC/P rates of the 12th month were significantly lower (Po0.05) than 3-month values. The SC/P rates of the 12th month were relatively higher than first scintigraphies but the difference was insignificant (P40.05). Conclusions: Within the limitations of this study, in which delayed loading was applied, we showed that osteoblastic activity persisted more in delay loaded implants than immediate and early loading. After 1 year, there was no cellular activity around two implants and this implied that two implants were sufficient for a total prosthesis.Öğe Farklı Polisaj Yöntemleri Uygulanan Seramiklerde Yüzey Pürüzlülüğünün İncelenmesi(2001) Aykent, Filiz; İnan, Özgür; Üşümez, Aslıhan; Sevimay, MüjdeSeramik restorasyonlarda daimi simantasyondan sonra da okluzal uyumlama yapılması ve porselenin intraoral olarak polisajı gerekli olabilir. Bu nedenle porselenin intraoral olarak nasıl en ideal polisajının yapılabileceğini bilmek önemlidir. Ceramco, Vitadur-N, Ivoclar, In-Ceram ve Cerec (Pro-CAD) porselenlerinin kullanıldığı bu çalışmada; her porselen grubu için 1 x1 cm genişliğinde ve 1 mm kalınlığında 40'ar adet porselen örnek hazırlandı. Standart olarak tesviyeleri tamamlanan tüm örnekler 50\mu'luk AI2O3 kullanılarak kumlandı ve "ultrasonic cleaner"da temizlendi. Her porselen grubundaki örnekler 10'arlı 4 gruba ayrıldılar. 1. gruptaki örnekler EDENTA porselen polisaj kiti kullanılarak dakikada 15.000 devirli tur motorunda 60sn polisaj işlemine tabi tutuldu. 2. gruptaki porselenler ise her markanın talimatına uygun olarak glaze işlemine tabi tutuldu. 3. gruptaki örnekler ise 1dak. süre ile 2W gücündeki Nd:YAG lazer ışınlarına maruz bırakıldı. Son grup örnekler ise hiçbir işleme tabi tutulmadan kontrol grubu olarak bırakıldılar. Örneklerin Mitutuyo Surftest cihazı kullanılarak yüzey pürüzlülükleri ölçüldü. Sonuçlar ANOVA ve Tukey istatistik analizleri kullanılarak değerlendirildi. Tüm porselen tiplerinde glaze yapılan gruplar ile lastikle polisajı yapılan gruplar arasında fark bulunamadı (p0.05). Ancak lazer işlemine tabi tutulan gruplar, hem glaze hem de lastikle polisajı yapılan gruplardan daha pürüzlü bulundu (p0.05). Kontrol grubu örnekleri de diğer üç gruptan önemli ölçüde pürüzlü bulundu (p0.05). Porselen tipleri arasında ise Vitadur-N ve Ceramco diğer porselen çeşitlerinden daha pürüzlü bulundu (p0.05). Bunları sırasıyla Ivoclar, In-Ceram ve Cerec porselenleri izledi. Bu porselen tipleri arasında ise pürüzlülük yönünden fark bulunamadı (p0.05).Öğe İmplant destekli köprü uygulamalarında okluzal yüzeylerde kullanılan restoratif materyallerin kuvvet dağılımına etkisinin incelenmesi(Selçuk Üniversitesi Sağlık Bilimleri Enstitüsü, 1997) İnan, Özgür; Kesim, BülentBu çalışmada implant destekli protetik restorasyonlarda kullanılan farklı materyallerin alveoler kemikte oluşturacağı fonksiyonel gerilimler fotoelastik kuvvet analizi yöntemi ile incelendi. Deneyler için alt yapı olarak 3.5mm çapmda 10mm uzunluğunda ITI Bonefit "hollow" silindir dental implantlar kullanıldı. Üst yapı için farklı protetik materyaller kullanıldı. Beş farklı protetik materyalin implant çevresinde oluşturacağı gerilimlerin incelenmesi için fotoelastik materyalden alt çene modeli hazırlandı. Bu modele 58 dikey ve eğimli yüklemeler yapıldı. Yüklemeler sonucu polariskop cihazında görülen kuvvet çizgilerinin renkli fotoğrafları çekildi. Bu çalışmada beş farklı protetik materyal üzerine uygulanan dikey ve eğimli yüklemeler sonucu ortaya çıkan gerilimler arasındaki fark istatistiksel olarak anlamlı bulunmuştur (p<0.01) Dikey ve eğimli yüklemeler sonucunda implantın apeks bölgesinde en fazla kuvvet iletimine sebep olan materyal Ceramco II porselen, ikinci sırada Biodent akrilik rezin olarak tespit edilmiştir. ArtGlass ve Elcebond CCV kompozit esaslı rezinler eşit derecede kuvvet iletimine sebep olurken, en az kuvvet iletimine sebep olan materyal ise Verebond metal alaşımı olarak bulunmuştur.Öğe İmplant Destekli Protezlerde Konvansiyonel Ve Dijital Ölçü: Sistematik Derleme(Selçuk Üniversitesi, 2021) Karaca, Simel; İnan, ÖzgürAmaç: Alçı modellere implant pozisyonlarını aktarabilmek için kullanılan direkt (açık kaşık) ve indirekt teknik (kapalı kaşık) olmak üzere 2 temel konvansiyonel ölçü tekniği vardır. Ağız içi tarayıcıların gelişmesiyle dijital ölçüler konvansiyonel implant ölçülerine alternatif olarak önerilmiştir. Bu derlemenin amacı, implant ölçülerinde konvansiyonel ve dijital yöntemlerin doğruluğunu değerlendirmektir. Gereç ve Yöntem: PubMed ve Google Akademik kullanılarak elektronik ortamda literatür taraması yapılarak 2015 yılı ve sonrasında yapılan çalışmalar dikkate alınmıştır. Bulgular: Dahil etme ve hariç tutma kriterleri uygulanarak 12 makale çalışmaya dahil edilmiştir. 10 makale in vitro ve 2 makale klinik çalışmadır. Üç in vitro çalışma ve bir klinik çalışma konvansiyonel implant ölçüsü ile dijital tekniğin doğruluğunu karşılaştırmıştır. Parsiyel dişsiz hastalar için 4 çalışmadan ikisi açık kaşık tekniğinin dijital ölçülerden daha doğru olduğunu, bir çalışma kapalı kaşık tekniğinin dijital ölçülerden daha doğru olduğunu ve bir çalışma ise konvansiyonel tekniğin dijital ölçü ile benzer sonuçlar verdiğini bildirmiştir. Tam dişsiz hastalar için 8 çalışmadan biri açık kaşık ölçü tekniğinin dijital ölçüyle benzer doğruluk gösterdiğini, iki çalışma splintli açık kaşık ölçü tekniğinin dijital ölçüden daha doğru olduğunu, üç çalışma dijital ölçünün daha doğru olduğunu ve bir çalışma ise splintli açık kaşık ölçü tekniğinin dijital ölçü ile benzer doğrulukta olduğunu bildirmiştir. Sonuç: İncelenen toplam 12 makaleden beşi implant ölçülerinde dijital tekniğin daha az doğru olduğunu belirtmiştir ve yedisi ise dijital ölçü kullanımını teşvik etmektedir.Öğe İmplant destekli restorasyonlarda farklı kanatlı köprü dizaynlarının kuvvet iletimine etkisinin fotoelastik kuvvet analizi metodu ile incelenmesi(1998) İnan, Özgür; Aykent, Filiz; Kesim, Bülent; Mert, M. AliBu çalışmada fotoelastik materyalden hazırlanan alt çene modelinde premolar bölgesine iki adet delikli silindir dental implant yerleştirildi. Implantların üzerine 1. grupta molar bölgede kanatlı köprü uzunluğu 10mm., 2. grupta ise 7mm. olan 10'ar adet standart köprüler hazırlandı. Kanatlı köprüye uygulanan 20kg'lık vertikal yük karşısında oluşan gerilimler fotoelastik kuvvet analizi yöntemi ile incelendi. 1. gruptaki köprülerde distal implant çevresinde oluşan gerilimler, 2. gruptaki köprülerden istatistiksel açıdan önemli ölçüde fazla bulunmuştur (p0.001). Mezial implant çevresinde oluşan gerilimler açısından iki grup arasında istatistiksel olarak önemli bir fark bulunamamıştır (p0.05). Her iki grupta da distal implantlarda gerilimler daha çok sıkışma tipinde olup apeksde yoğunlaşırken, mezial implantta ise daha çok gerilme tipi kuvvetler oluşmuştur. Yine iki grupta da distal implant da oluşan gerilimler, mezial implantta oluşan gerilimlerden istatistiksel açıdan önemli ölçüde fazla bulun-muştur (p0.001).Öğe Implant-Supported Overdenture Therapy: A 3-to 8-Year Prospective Study(2000) İnan, Özgür; Aykent, Filiz; Alptekin, NilgünInflammatory changes in peri-implant soft tissues and loss of alveolar bone can develop as in periodontal diseases. This clinical phenomena has been described as periimplantitis. Microorganisms such as Gram-negative anaerobic rods, spirochetes, and bacteroides that are seen in subgingival flora in periodontitis have also been found in sulcular microflora in periimplantitis. The purpose of this study was to evaluate periimplant tissue changes in totally edentulous patients who had implant-supported overdentures for 3 to 8 years (5-5.5 years) clinically from both a subjective and an objective point of view. The clinical parameters used in this study can be helpful in the evaluation of periimplant tissue health.Öğe Kısmi ve Tam Dişsiz Hastaların Protetik Tedavisinde Spline Implantların Kullanımı (Dört Vaka Raporu)(1998) Aykent, Filiz; İnan, Özgür; Mutlu, M. NecipAmaç: implant-abutment bölgesinde daha kuvvetli ve stabil bir birleşmeyi sağladığı savunulan spline implant sisteminin kısmi ve tam dişsiz hastalarda uygulanımı hakkında bilgi vermektir. Vaka Raporu: 2 tam dişsiz ve 2 kısmi dişsiz olmak üzere 4 hastaya implant-abutment arasında yeni bir dizayn ile bağlanma sağlayan Calcitek firmasına ait toplam 14 adet spline implant uygulanmıştır. Protezleri yapıldıktan sonra hastaların 12 aylık klinik takip ve değerlendirmeleri tamamlanmıştır. Sonuç: Hastaların 12 aylık takip dönemlerinde implant kırılması, abutment vida kırılması ya da gevşemesi ve üst yapıya ait kırılma gihi herhangi bir komplikasyon gözlenmemiştir. Ancak implant-abutment bölgesinde, diğer sistemlere göre daha kuvvetli ve stabil bir birleşmeyi sağladığı rapor edilen bu yeni sistemin başarısı hakkında karar verebilmek için. hastaların daha uzun dönem takip edilmesi ve implant sayısının artırılması gerekmekledir.Öğe Use of the fertilized hen's egg in the evaluation of embryotoxicity of dental alloys(WILEY-LISS, 2005) Durmuş, Ercan; İnan, Özgür; Çelik, İlhami; Sur, Emrah; Özkan, Yasemin; Acar, Aslı; Aydın, Mehmet FarukIn this study, embryotoxic effects of five commercially available dental alloys were investigated by using fertilized hens' eggs. One sample of each alloy was conditioned in one of the conditioning media, physiological saline (PS), 0.1 M phosphate-buffered saline (PBS, pH 7.4), and 0.1 M protein (3% bovine serum albumin, BSA) containing PBS (pH 6.8), respectively. The test solutions were injected into the fertilized hen's eggs via air sac at the beginning of the incubation. Various concentrations of a highly embryotoxic substance, AFB(1), was also used as positive control test material. Mortality of the AFB(1) treatment groups increased with increasing concentrations of AFB(1), and the mortality values were significantly (p < 0.05) higher than those of the controls and eluent injected groups. The eluents of five commercially available dental alloys tested in the study did not have significant embryotoxic effects. Cu- and Pd-containing alloys displayed relatively high but statistically insignificant embryotoxic effects. Chick embryo might be used in determination of the embryotoxic effects of the dental alloys with its several advantages. Nevertheless, the test should be further standardized and new methods such as micronucleus test showing possible genotoxic effects of the materials should be used. (C) 2004 Wiley Periodicals, Inc.
