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Öğe Adolescent With Variant Angina(Blackwell Publishing Asia, 2003) Karaaslan, Sevim; Baysal, Tamer; Başpınar, Osman; Oran, Bülent[Abstract not Available]Öğe The association between pulmonary arterial hypertension and malnutrition in children with congenital heart diseases with left-to-right shunt: an observational study(TURKISH SOC CARDIOLOGY, 2012) Altın, Hakan; Karataş, Zehra; Sap, Fatih; Alp, Hayrullah; Baysal, Tamer; Karaaslan, Sevim; Oran, BülentObjective: To evaluate the association between the degree of pulmonary arterial hypertension (PAH) and the level of malnutrition in children with acyanotic congenital heart diseases and left-to-right shunt, and especially to evaluate the development rates of malnutrition in patients with borderline PAH. Methods: The study was performed with data of 327 patients with acyanotic congenital heart diseases and left-to-right shunt and underwent cardiac catheterization between January 2001-February 2011. The design of the study was retrospective and observational. All patients were evaluated with anthropometric measurements, echocardiography and cardiac catheterization. They were classified according to the mean pulmonary artery pressure and level of malnutrition. Chi-square, ANOVA and Kruskal-Wallis tests were used for statistical analysis. Normally and abnormally distributed data were analyzed with Pearson and Spearman correlation tests respectively. Results: Malnutrition was detected in 94.8% of patients with PAH and 17.2% of no PAN patients according to Gomez classification (p<0.001). In addition, malnutrition was detected in 23.5% (16/68) of borderline PAN group. A negative association was detected between mean pulmonary arterial pressure and body weight for age (Gomez) and z scores of weight (p<0.001 for all). Z scores of weight and height were significantly decreased in patients with PAH in contrast to no PAH group (p<0.001, p<0.01 respectively). There was no statistical difference between no PAH and borderline PAH groups according to Gomez classification and relative body weight formula, however z scores of weight in borderline PAN group were decreased compared with no PAH group (p<0.001). Conclusion: A positive association was detected between the degrees of PAH and level of malnutrition in children with a cyanotic congenital heart diseases with left-to-right shunt. Borderline PAH may be a predisposing factor for malnutrition and further studies are needed for this subject. (Anadolu Kardiyol Derg 2012; 12: 150-9)Öğe Beta-blocker treatment in an adolescent with amitriptyline intoxication(GALENOS YAYINCILIK, 2007) Baysal, Tamer; Oran, Buelent; Dogan, Mustafa; Cimen, Derya; Elmas, Sefika; Karaaslan, Sevim[Abstract not Available]Öğe Beta-Blocker Treatment in an Adolescent With Amitriptyline Intoxication(2007) Baysal, Tamer; Oran, Bülent; Doğan, Mustafa; Çimen, Derya; Elmas, Şefika; Karaaslan, SevimAmitriptyline is one of the major tricyclic antidepressants (TCA) (1). Among the antidepressants, TCAs have been the most common poisons used in suicide (2). Tricyclic antidepressants poisoning results in hypotension, cardiac dysrhythmia, depression of the central nervous system (CNS) and seizures, and is a major cause of death by poisoning in the UK (3). The most common cause of death after TCA overdose is myocardial depression with refractory hypotension, ventricular tachycardia, or ventricular fibrillation (4). Current therapy includes vasopressors for hypotension, sodium bicarbonate for dysrhythmias, and benzodiazepines for seizures (3). We report a case of a child who was successfully treated with beta-blocker in severe amitriptyline intoxication.Öğe Cardiac Functions Evaluated with Tissue Doppler Imaging in Childhood Cancers Treated with Anthracyclines(Informa Healthcare, 2010) Baysal, Tamer; Köksal, Yavuz; Oran, Bülent; Şen, Metin; Ünal, Ekrem; Çimen, DeryaAim: The aim of this study was to assess the cardiac functions using conventional echocardiography and tissue Doppler imaging in childhood cancers treated with anthracyclines. Methods: The study group was selected from the patients admitted to the pediatric oncology department for a treatment protocol that included doxorubicin. Body surface area was calculated and complete 2-dimensional, M-mode, pulse wave Doppler and pulse wave tissue Doppler echocardiographic examinations were performed just before the first treatment and at least 6 months after the last treatment. Results: This study included 20 patients (12 males and 8 females). Mean cumulative antracycline dose was 189 +/- 102.90 mg/mÖğe Cardiac troponin I elevation in pediatric cardiac catheterization(2005) Baysal, Tamer; Oran, Bülent; Başpınar, Osman; Doğan, Mustafa; Karaaslan, SevimAmaç: Bu çalışmanın amacı çocuklarda uygulanan kalp kateterizasyonunun miyokard hasarına yol açıp açmadığını prospektif olarak araştırmaktır. Yöntemler: Çalışma bölümümüzde teşhis amaçlı kalp kateterizasyonu uygulanan bütün hastalarda yapıldı. İşlemden hemen önce serum örnekleri alındı. İkinci serum örnekleri işlemden sonraki 4-6 saat içinde alındı. Bu serumlarda kardiyak troponin I ve kreatin-kinaz izoenzim-MB kantitatif olarak bakıldı. Bulgular: Teşhis amaçlı kalp kateterizasyonu 30 hastaya uygulandı. Çalışmada 17 erkek ve 13 kız hasta vardı. Ortanca yaşları 12 ay (1 ile 204 ay arasında), ortanca kilo değeri 8 kilogram (2.1 ile 45 kilogram arasında) idi. Kardiyak troponin I (işlem öncesi 0.210.04 ng/ml, işlem sonrası 1.161.40 ng/ml) ve kreatin kinaz izoenzim-MB ( işlem öncesi 26.687.53 U/L, işlem sonrası 41.6522.12 U/L) düzeylerindeki artışlar istatistiksel olarak anlamlı idi (p 0.05). Sonuç: Bu çalışma ile pediatrik yaş grubunda yapılan teşhis amaçlı kalp kateterizasyonu işlemi sırasında kardiyak troponin I ve kreatin kinaz izoenzim-MB düzeylerinde artış olduğu gösterildi.Öğe Cardiac Troponin-I in the Serum of Infants of Diabetic Mothers(Greenwich Medical Media Ltd, 2003) Oran, Bülent; Çam, Lokman; Başpınar, Osman; Baysal, Tamer; Reisli, İsmail; Peru, Harun; Karaaslan, Sevim; Koç, Hasan; Gürbilek, MehmetA transient form of hypertrophic cardiomyopathy has been previously described in infants of diabetic mothers. When it occurs, it is generally benign. The purpose of our study was to establish the extent of injury to the cardiomyocytes in symptomatic and asymptomatic patients with and without hypertrophic cardiomyopathy. Thus, we compared 35 consecutive patients to 20 healthy controls, establishing the significance, if any, of differences in cardiac troponin-I and creatine kinase, including its MB-fraction, and seeking to establish the value of these parameters in the diagnosis of cardiac injury. We also determined to levels of glucose and insulin in the serum, and took note of electrocardiographic and echocardiographic investigations. Values were determined at the 1st and 7th days after admission in the patients, while parameters were measured in the control group only on the first day. We found that the levels of cardiac troponin-I in the serum, known to be a marker for cardiac injury, were significantly elevated in symptomatic patients with life-threatening respiratory or haemodynamic distress. We speculate that transient ventricular hypertrophy is neither the cause nor the consequence of damage to the cardiomyocytes. It would be interesting, nonetheless, to determine the relationship, if any, between cardiomyocytic damage and clinical outcome.Öğe Çocukluk döneminde künt göğüs travması sonrası koroner arter zedelenmesine bağlı gelişen ventriküler septal defekt(2012) Karataş, Zehra; Şap, Fatih; Altın, Hakan; Alp, Hayrullah; Baysal, Tamer; Karaaslan, SevimKünt göğüs travması ile ilişkili kardiyak etkilenme, literatürde çocuklarda genellikle olgu sunumları şeklinde bildirilmiştir ve travmaya bağlı interventriküler septum rüptürü gelişmesi oldukça nadirdir. Çocuklarda göğüs kafesi yapılarının esnek olması nedeniyle görünür bir travma belirtisi olmadan da interventriküler septum rüptürü gelişebilmektedir. Bu yazıda, trafik kazası sonrası sol ön inen koroner arter zedelenmesine bağlı mid-müsküler bölgede interventriküler septum rüptürü ve sol ventrikülde psödoanevrizma gelişen 7 yaşında bir erkek olgu sunuldu. Künt göğüs travması sonrasında fiziksel incelemede üfürüm tespit edilen hastalarda kardiyak zedelenme olabileceği düşünülmeli ve elektrokardiyografide iskemi bulguları saptananlarda koroner arterlerin de etkilenmiş olabileceği unutulmamalıdır.Öğe Comparison of left and right ventricular pulsed and tissue Doppler myocardial performance index values using Z-score in newborns with hypoxic-ischemic encephalopathy(TURKISH SOC CARDIOLOGY, 2011) Alp, Hayrullah; Karaaslan, Sevim; Baysal, Tamer; Oran, Bulent; Ors, RahmiObjective: The aim of the study is determination of myocardial performance index (MPI/Tei index) using pulsed (PD) and tissue Doppler (TD) techniques to show cardiac response in newborns with hypoxic-ischemic encephalopathy (HIE) and healthy newborns and eventually evaluation of the differences between these two techniques. Methods: The study is a prospective observational study. Twenty term newborns diagnosed as perinatal asphyxia during postnatal 24 hours due to the defined criteria and fifty healthy term neonates as control group were included the study. Hypoxic group was divided into two groups with Sarnat stages, Sarnat Stage 1 and 2-3. MP's (Tei indexes) were calculated with PD and TO echocardiographic techniques in all groups after the 24 hours of birth and one year later. The statistical differences between same techniques were calculated with Kruskal-Wallis test and Z score was used to compare the superiority of two techniques. Results: The MPI values calculated by PD (0.41 +/- 0.04, 0.51 +/- 0.02) and TD (0.59 +/- 0.04, 0.51 +/- 0.02) during the first day of life in Sarnat Stage 2-3 in both ventricles were significantly higher than the control group (p<0.01, p<0.02, p<0.03). While the Z score, calculated for MPI measured by PD and TD methods, were found similar in both ventricles in Sarnat Stage 1 and control groups, it was significantly different in other groups of Sarnat stages. Conclusion: The degree of cardiac response in neonates with HIE is associated with the severity of hypoxia. MPI values are not different from the controls in newborns received mild hypoxia while they are higher in the patients who were received moderate or severe hypoxia. Any advantage could not be found between two techniques according to the measurement values, but higher variability in the value of MPI, measured by TO method, calculated from moderate and severe hypoxia group was detected. (Anadolu Kardiyol Derg 2011; 11: 719-25)Öğe Criteria for Judging the Improvement in Subclinical Rheumatic Valvitis(CAMBRIDGE UNIV PRESS, 2003) Karaaslan, Sevim ; Demiroren, Saadet; Oran, Bülent; Baysal, Tamer; Başpinar, Osman; Uçar, CananRecent technical improvements in cross-sectional echocardiography have made it possible to detect even mild organic regurgitation of the mitral and aortic valves in patients with acute rheumatic fever. To determine the prevalence and prognosis of subclinical valvitis, we have analyzed 104 patients with acute rheumatic fever referred to our institution. Of 53 patients who had no murmur, 22 of them with polyarthritis, 29 with chorea, and 2 with polyarrhritis and chorea, 23 (43.4%) had subclinical valvitis. Isolated mitral regurgitation was the most common valvar lesion, seen in 82.6% of the patients. Isolated aortic regurgitation was detected in 4.4%, of the cases, and combined mitral and aortic regurgitation in the remaining 13%. During follow-up, the degree of mitral regurgitation improved in 59.1%, decreased in 18.2%, and increased or remained unchanged in 22.7% according to the length of colour jet. According to criterions of velocity, mitral regurgitation improved in 86.4% of the patients, and increased or unchanged in the remaining 13.6%. Mitral regurgitation disappeared completely in 6 of the patients (27.3%) as judged according to both the length of colour jet and the velocity of regurgitation. Aortic regurgitation improved in all the patients with this problem, disappearing completely in two of the four. Based on this experience, we suggest that not only the disappearance of regurgitation, but also improvements in the echocardiographic diagnostic criterions of regurgitation, such as the length of the colour jet less than 1 cm, or velocity less than 2.5 m/s, or indicative of regurgitation that is either intermittent or of short duration, should also be considered as criterions indicating improvement in valvar regurgitation in patients with subclinical rheumatic valvitis.Öğe Dilated cardiomyopathy due to aortic coarctation in childhood(2011) Karataş, Zehra; Şap, Fatih; Altın, Hakan; Alp, Hayrullah; Baysal, Tamer; Karaaslan, SevimAort koarktasyonuna bağlı dilate kardiyomyopati ise nadir görülmektedir. Yirmibir aylık erkek hasta öksürük, takipne ve kardiyomegali mevcuttu. Ekokardiyografide önemli derecede aort koarktasyonunun olduğu izlendi. Balon anjiyoplasti ile yeterli düzelme olmaması üzerine bir ay sonra cerrahi girişim yapıldı. Bu vaka aort koaktasyonu tanısında eş zamanlı brakial ve femoral nabız muayenesinin ne kadar önemli olduğunu ve gecikilmiş vakaların dilate kardiyomiyopati adayı olabileceklerini hatırlatmak amacıyla sunuldu. Çocuklarda dilate kardiyomiyopati nedenlerinin ayırıcı tanısı yapılırken aort koarktasyonunun akılda bulundurulması gerekir. İdiyopatik dilate kardiyomiyopati tanısını kesin olarak koymadan önce miyokard disfonksiyonu yapan muhtemel spesifik nedenlerin araştırılması büyük önem arzeder. Çünkü bizim vakamızda da görüldüğü üzere, kardiyomiyopatinin bazı nedenlerinin tamamen tedavi şansı bulunmaktadır.Öğe Dilated cardiomyopathy due to aortic coarctation in childhood(2011) Karataş, Zehra; Şap, Fatih; Altın, Hakan; Alp, Hayrullah; Baysal, Tamer; Karaaslan, SevimDilated cardiomyopathy (DCM) is rarely seen secondary to Coarctation of aorta. Twenty-one months old male was referred to our hospital because of tachypnea, coughing and cardiomegaly. Echocardiography revealed most importantly CoA. Because sufficient improvement could not be acquired with interventional balloon angioplasty, he had surgical operation after one month. Coarctation of aorta should be taken into consideration in the differential diagnosis of causes of DCM in chidren. It is also so important that before we decide definitely for any patient presenting with a DCM as an idiopathic cardiomyopathy, we must rule out all possible specific causes of myocardial dysfunction. Because some of specific etiological factors of cardiomyopathies can be completely treatable, just like in our patient.Öğe Dispersion Durations of P-wave and QT Interval in Children With Congenital Heart Disease and Pulmonary Arterial Hypertension(SPRINGER, 2013) Sap, Fatih; Karataş, Zehra; Altın, Hakan; Alp, Hayrullah; Oran, Bülent; Baysal, Tamer; Karaarslan, SevimThis study aimed to investigate homogeneity disorders of ventricular repolarization and atrial conduction via QT dispersion and P-wave dispersion in children with congenital heart disease (CHD) and pulmonary arterial hypertension (PAH). Three groups of 20 each were generated and involved in this study. The first group included 20 children with both CHD and PAH. The second group consisted of 20 children with CHD but no PAH, and the third group was composed of 20 age- and sex-matched healthy children. Electrocardiographic records were used to determine P-wave, QT, and corrected QT (QTc) dispersions. The pulmonary hypertension group compared with the group having no pulmonary hypertension and the control group showed a significantly longer P-wave dispersion duration (39.10 +/- A 9.54 vs. 26.30 +/- A 4.99 ms, p < 0.001; and 24.80 +/- A 6.94 ms, p < 0.001, respectively) and QT dispersion duration (52.80 +/- A 15.11 vs. 37.60 +/- A 6.00 ms, p < 0.001; and 35.00 +/- A 7.77 ms, p < 0.001, respectively). In addition, the durations of maximum QTc and QTc dispersion were significantly longer in pulmonary hypertension group than in the other two groups. The risk of atrial and ventricular arrhythmia was found to be increased in the patients with both CHD and PAH. Physicians should pay close attention to possible atrial and ventricular arrhythmias during the treatment and follow-up evaluation of these patients.Öğe Double aortic arch with mirror-image dextrocardia [Ayna hayali dekstrokardi ile birlikte çift arkus aorta](2013) Altın, Hakan; Alp, Hayrullah; Şap, Fatih; Karataş, Zehra; Baysal, Tamer; Karaaslan, SevimDouble aortic arch (DAA) is a very rare congenital vascular anomaly, characterized by the encircling trachea and esophagus, resulting feeding and/or respiratory problems. In this article, a two-month-old girl with situs inversus totalis and DAA was presented. The baby was symptomatic with noisy breathing and coughing since birth. Double aortic arch was detected by echocardiography, barium esophagography, cardiac MRI and conventional angiography. The present report emphasis that vascular ring should have been evaluated in a patient with respiratory and/or feeding problems. Chest radiography, barium esophagography, echocardiography, multislice computed tomography, magnetic resonance imaging angiography and conventional cardiovascular angiography can be used for the diagnosis of DAA.Öğe Hipoksik iskemik ensefalopatili yenidoğanlarda sol ve sağ ventrikül “pulsed” ve doku Doppler miyokart performans indeks değerlerinin Z-skorla karşılaştırması(2011) Alp, Hayrullah; Karaaslan, Sevim; Baysal, Tamer; Oran, Bülent; Örs, RahmiAmaç: Çalışmanın amacı; hipoksik iskemik ensefalopatili (HİE) ve sağlıklı term yenidoğan bebeklerde, kardiyak etkilenmeyi göstermek amacı ile pulsed (PD) ve doku Doppler (DD) tekniklerini kullanarak miyokart performans indeksini (MPİ/Tei indeksi) belirlemek ve bu iki teknik sonuçları arasında ortaya çıkan farklılıkları değerlendirmektir. Yöntemler: Çalışma prospektif gözlemsel bir çalışmadır. Postnatal ilk 24 saat içinde belirlenen kriterlere göre perinatal asfiksi tanısı konulan 20 term yenidoğan ve kontrol grubu olarak sağlıklı, 50 term yenidoğan bebek çalışmaya alındı. HİE grup Sarnat evrelemesine göre Sarnat Evre 1 ve 2-3 olmak üzere iki gruba ayrıldı. Kontrol ve hasta gruplarına doğumdan sonraki ilk 24 saat içerisinde ve bir yıl sonra, PD ve DD ekokardiyografi teknikleri uygulanarak MPI hesaplandı. Aynı ölçüm teknikler ile elde edilen veriler Kruskal-Wallis testi ile iki tekniğin birbirine üstünlüğü ise Z skoru olarak hesaplandı. Bulgular: Sarnat evre 2-3 grubunda, hayatın ilk gününde her iki ventrikülde PD (0.410.04, 0.510.02) ve DD (0.590.04, 0.510.02) ile bakılan bakılan MPİ kontrol grubuna göre anlamlı derecede yüksek bulundu (p0.01, p0.02, p0.03). Pulsed ve doku Doppler ile elde edilen MPİ için hesaplanan Z skoru, kontrol grubu ve Sarnat Evre 1 grubunda her iki ventrikül için benzer bulunurken, diğer Sarnat gruplarında anlamlı olarak farklı olduğu görüldü. Sonuç: Hipoksik iskemik ensefalopatili yenidoğanlarda kardiyak fonksiyonlar olumsuz yönde etkilenmekte olup bu durumun, hipoksinin ağırlığı ile ilişkili olduğu bulunmuştur. MPİ, hafif hipoksiye maruz kalan yenidoğanlarda kontrol grubundan farksız iken, orta ve ağır hipoksiye maruz kalmış yenidoğanlarda daha büyüktür. İki tekniğin ölçüm değerleri açısından birbirine üstünlüğü bulunamamış ancak orta ve ağır hipoksik grupta DD ile elde edilen MPİ’deki Z skor değişiminin daha büyük olduğu saptanmıştır. (Anadolu Kardiyol Derg 2011; 11: 719-25)Öğe Is Myocardial Performance Index Useful in Differential Diagnosis of Moderate and Severe Hypoxic-İschaemic Encephalopathy? A Serial Doppler Echocardiographic Evaluation(Cambridge Univ Press, 2012) Karaarslan, Sevim; Alp, Hayrullah; Baysal, Tamer; Çimen, Derya; Örs, Rahmi; Oran, BulentIntroduction: The aim of this study was to investigate the importance of myocardial performance index as an additive criterion to Sarnat criteria in differential diagnosis of newborn babies with moderate and severe hypoxic-ischaemic encephalopathy. Methods: Our study group included 50 healthy term newborn babies and 20 newborn babies with hypoxic ischaemic encephalopathy. The 20 newborn babies with hypoxic-ischaemic encephalopathy were scored using Sarnat grades. Left and right ventricular functions were determined on the first day and thereafter in the 1, 3-4, 6-7, and 11-12 months of life by M-Mode and pulsed Doppler. Results: Myocardial performance indexes of the left ventricle were significantly higher in the severe hypoxic ischaemic encephalopathy group than in the control group during the first, second, and third analyses (p = 0.01, p = 0.02, p = 0.02, respectively) and only during the first analysis (p = 0.01) in the moderate hypoxic-ischaemic encephalopathy group. In addition, the myocardial performance indexes of the right ventricle were significantly higher during the first, second, and third analyses in both severe and moderate hypoxic-ischaemic encephalopathy groups than in the control group (p = 0.01, all). Hypoxia-induced alterations last longer in the right ventricle than in the left ventricle in the moderate group, as during the second and third analyses myocardial performance index continues to be higher than the control group. Conclusion: Myocardial performance indexes for the left and right ventricles were significantly higher in both severe and moderate hypoxic-ischaemic encephalopathy groups than in the control group during the first analysis, and myocardial performance index greater than or equal to 0.5 can be used in order to distinguish moderate and severe hypoxic-ischaemic encephalopathy babies according to Sarnat grades as a discriminative additive criterion.Öğe Isokinetic strength of the trunk flexors and extensors in ankylosing spondylitis(IOS PRESS, 2013) Durmus, Bekir; Sahin, Nilay; Baysal, Ozlem; Ersoy, Yuksel; Baysal, Tamer; Koca, Tuba Tulay; Altay, ZuhalBACKGROUND: Objective measurement of trunk muscles strength in ankylosing spondylitis (AS) may provide clinical information that can be used to evaluate functional disability. OBJECTIVE: To compare the isokinetic strength of trunk muscles in AS patients with healthy subjects. METHODS: Thirty-four patients with AS and thirty-one healthy subjects were enrolled. Patients with spinal ankylosis and bridged syndesmophytes in the lumbar and dorsal vertebrae were excluded. Trunk flexor and extensor strength was measured at: 60 and 90 degrees/sec. RESULTS: When compared with the control group, AS patients demonstrated 38% and 24% decrease in the extensor and flexor strength, respectively (p < 0.05). In addition, the flexor/extensor strength ratio was 1.0 and 0.8 in the patients and control subjects, respectively. CONCLUSIONS: In view of the relatively selective extensor weakness we recommend assessment of trunk muscle strength in these patients for guiding clinicians regarding possible reconditioning exercises in the early period of AS.Öğe İzole soldan sağa şantlı doğumsal kalp hastalığı olan çocuklarda miyokard performans indeksinin incelenmesi(Selçuk Üniversitesi Tıp Fakültesi, 2003) Baysal, Tamer; Oran, BülentAtriyal, ventriküler veya büyük damarlar arasındaki izole soldan sağa şantlı lezyonlar çocukluk çağında görülen en sık kalp anormallikleridir. Doğuştan kalp hastalığı olan hastalarda ventrikül geometrisi bozulacağı için ventrikül fonksiyonlarını değerlendirmede bazı zorluklar olabilmektedir. Ventrikül fonksiyonlarım değerlendirmede Doppler eko yöntemi ile elde edilen ve ventrikülün geometrik şekline bağımlı olmayan miyokard performans indeksi erişkin ve çocuklarda araştırılarak kullanılmaya başlandı. Miyokard performansindeksi izovolumik zaman aralıklarının ejeksiyon zamanına bölünmesi ile elde edilir. Ventriküllerin ön ve art yük değişikliklerinde bu indeksin nasıl etkilendiği araştırılmalıdır. Bu çalışma izole soldan sağa santiarın neden olduğu ön yük değişikliklerinde sağ ve sol ventriküler miyokard performans indeksinin nasıl etkilendiğini araştırmak amacı ile planlandı. Yaşlan 6 ay ile 148 ay arasında 17 ASD' li, yaşlan 2 ay ile 160 ay arasında 23 VSD' li ve yaşlan 3 ay ile 160 ay arasında 24 normal çocukta sol ve sağ ventrikül için miyokard performans indeksi ölçüldü. Sol ventrikül için miyokard performans indeksi ASD, VSD ve kontrol grubunda sırası ile 0.38, 0.37 ve 0.32 iken sağ ventrikül için miyokard performans indeksi sırası ile 0.24, 0.21 ve 0.20 bulundu. Gruplar arasında sol ve sağ ventrikül miyokard performans indeksleri yönünden istatiksel açıdan anlamlı bir fark yoktu. Bu çalışma ile ventrikül fonksiyonlanm ölçmeye yarayan miyokard performans indeksinin ön yük değişikliklerinden bağımsız olduğu gösterildi.Öğe Kluver-Bucy syndrome in a boy with non-Hodgkin lymphoma(TAYLOR & FRANCIS INC, 2007) Unal, Ekrem; Koksal, Yavuz; Baysal, Tamer; Energin, Meltem; Aydin, Kursad; Caliskan, UmranKluver-Bucy syndrome is a rare neurobehavioral condition characterized by visual agnosia, excessive oral tendency, hypermetamorphosis, placidity, altered sexual behaviors, and changes in dietary habits. The authors report a case of Kluver-Bucy syndrome in a 10-year-old boy with non-Hodgkin lymphoma after intratechal methotrexate administration. He was treated by risperidone without any sequels.Öğe Left ventricular diastolic function evaluated with tissue Doppler imaging in children with familial Mediterranean fever(SPRINGER LONDON LTD, 2009) Baysal, Tamer; Peru, Harun; Oran, Bulent; Sahin, Tahir Kemal; Koksal, Yavuz; Karaaslan, SevimThe aim of this study was to assess the left ventricular diastolic function using conventional echocardiography and tissue Doppler imaging in children with familial Mediterranean fever. This study included 29 (13 males and 16 females) patients and 30 healthy subjects as controls. Body mass index was calculated and arterial blood pressure was monitored. After an overnight fast, venous blood samples were taken and serum amyloid A protein, C-reactive protein, serum-fasting glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, very low density lipoprotein cholesterol, and serum low-density lipoprotein cholesterol levels were measured. A complete 2-dimensional, M-mode, pulse wave Doppler, and pulse wave tissue Doppler echocardiographic examination was performed. There were no significant differences between the groups regarding age, body mass index values, systolic and diastolic blood pressures, heart rates, serum-fasting glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, very low density lipoprotein cholesterol, and serum low-density lipoprotein cholesterol. Serum levels of inflammatory markers were higher in patients' group (C-reactive protein and serum amyloid A protein levels were 10.84 mg/dl, 22.32 mg/l in patients' group, respectively, and 4.11 mg/dl, 3.65 mg/l, respectively, in the healthy controls.) Peak mitral A wave, E and A wave ratio differed significantly in both groups. There were statistically significant differences regarding parameters observed by tissue Doppler imaging such as E'm, A'm, E'm, and A'm ratio between patients' group and controls. Tissue Doppler imaging provided additional information on left ventricular diastolic function. While systolic functions were in normal range, some of the diastolic function parameters were impaired in patients with familial Mediterranean fever during childhood.
