Cardiac Troponin-I in the Serum of Infants of Diabetic Mothers
Yükleniyor...
Dosyalar
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Greenwich Medical Media Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
A transient form of hypertrophic cardiomyopathy has been previously described in infants of diabetic mothers. When it occurs, it is generally benign. The purpose of our study was to establish the extent of injury to the cardiomyocytes in symptomatic and asymptomatic patients with and without hypertrophic cardiomyopathy. Thus, we compared 35 consecutive patients to 20 healthy controls, establishing the significance, if any, of differences in cardiac troponin-I and creatine kinase, including its MB-fraction, and seeking to establish the value of these parameters in the diagnosis of cardiac injury. We also determined to levels of glucose and insulin in the serum, and took note of electrocardiographic and echocardiographic investigations. Values were determined at the 1st and 7th days after admission in the patients, while parameters were measured in the control group only on the first day. We found that the levels of cardiac troponin-I in the serum, known to be a marker for cardiac injury, were significantly elevated in symptomatic patients with life-threatening respiratory or haemodynamic distress. We speculate that transient ventricular hypertrophy is neither the cause nor the consequence of damage to the cardiomyocytes. It would be interesting, nonetheless, to determine the relationship, if any, between cardiomyocytic damage and clinical outcome.
Açıklama
Anahtar Kelimeler
Infants of Diabetic Mothers, Hypertrophic Cardiomyopathy, Cardiac Troponin-I, Creatine Kinase, Creatine Kinase-MB
Kaynak
Cardiology in the Young
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
13
Sayı
3
Künye
Oran, B., Çam, L., Başpınar, O., Baysal, T., Reisli, İ., Peru, H., Karaaslan, S., Koç, H., Gürbilek, M., (2003). Cardiac Troponin-I in the Serum of Infants of Diabetic Mothers. Cardiology in the Young, 13(3), 248-252. Doi: 10.1017/S1047951103000489
