Cardiac Troponin-I in the Serum of Infants of Diabetic Mothers

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dc.contributor.authorOran, Bülent
dc.contributor.authorÇam, Lokman
dc.contributor.authorBaşpınar, Osman
dc.contributor.authorBaysal, Tamer
dc.contributor.authorReisli, İsmail
dc.contributor.authorPeru, Harun
dc.contributor.authorKaraaslan, Sevim
dc.contributor.authorKoç, Hasan
dc.contributor.authorGürbilek, Mehmet
dc.date.accessioned2020-03-26T16:45:28Z
dc.date.available2020-03-26T16:45:28Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractA transient form of hypertrophic cardiomyopathy has been previously described in infants of diabetic mothers. When it occurs, it is generally benign. The purpose of our study was to establish the extent of injury to the cardiomyocytes in symptomatic and asymptomatic patients with and without hypertrophic cardiomyopathy. Thus, we compared 35 consecutive patients to 20 healthy controls, establishing the significance, if any, of differences in cardiac troponin-I and creatine kinase, including its MB-fraction, and seeking to establish the value of these parameters in the diagnosis of cardiac injury. We also determined to levels of glucose and insulin in the serum, and took note of electrocardiographic and echocardiographic investigations. Values were determined at the 1st and 7th days after admission in the patients, while parameters were measured in the control group only on the first day. We found that the levels of cardiac troponin-I in the serum, known to be a marker for cardiac injury, were significantly elevated in symptomatic patients with life-threatening respiratory or haemodynamic distress. We speculate that transient ventricular hypertrophy is neither the cause nor the consequence of damage to the cardiomyocytes. It would be interesting, nonetheless, to determine the relationship, if any, between cardiomyocytic damage and clinical outcome.en_US
dc.identifier.citationOran, B., Çam, L., Başpınar, O., Baysal, T., Reisli, İ., Peru, H., Karaaslan, S., Koç, H., Gürbilek, M., (2003). Cardiac Troponin-I in the Serum of Infants of Diabetic Mothers. Cardiology in the Young, 13(3), 248-252. Doi: 10.1017/S1047951103000489
dc.identifier.doi10.1017/S1047951103000489en_US
dc.identifier.endpage252en_US
dc.identifier.issn1047-9511en_US
dc.identifier.issue3en_US
dc.identifier.pmid12903871en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage248en_US
dc.identifier.urihttps://dx.doi.org/10.1017/S1047951103000489
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18386
dc.identifier.volume13en_US
dc.identifier.wosWOS:000184225700005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorOran, Bülent
dc.institutionauthorÇam, Lokman
dc.institutionauthorBaşpınar, Osman
dc.institutionauthorBaysal, Tamer
dc.institutionauthorReisli, İsmail
dc.institutionauthorPeru, Harun
dc.institutionauthorKaraaslan, Sevim
dc.institutionauthorKoç, Hasan
dc.institutionauthorGürbilek, Mehmet
dc.language.isoenen_US
dc.publisherGreenwich Medical Media Ltden_US
dc.relation.ispartofCardiology in the Youngen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectInfants of Diabetic Mothersen_US
dc.subjectHypertrophic Cardiomyopathyen_US
dc.subjectCardiac Troponin-Ien_US
dc.subjectCreatine Kinaseen_US
dc.subjectCreatine Kinase-MBen_US
dc.titleCardiac Troponin-I in the Serum of Infants of Diabetic Mothersen_US
dc.typeArticleen_US

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