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Öğe Add-on therapy with pramipexole in treatment resistant dysthymic disorder: A case report(KURE ILETISIM GRUBU A S, 2009) Zeytinci, Esra; Uguz, Faruk; Sahingoz, Mine; Sari, Serap; Kayhan, FatihAdd-on therapy with pramipexole in treatment resistant dysthymic disorder: A case report Despite a wide range of alternative antidepressant drugs, a considerable rate of patients with dysthymic disorder do not response to these treatments. Usually combined pharmacological drugs and augmentation therapies are used to manage this chronic psychiatric disorder. Pramipexole, a new dopamine agonist, is approved for Parkinson's disease and restless leg syndrome but accumulating evidence suggests the usage of the drug as an antidepressant. We present a young man with a history of dysthymic disorder for 15 years who improved after adding low dose pramipexole to the prior treatment.Öğe Anti-tumor necrosis factor-alpha therapy is associated with less frequent mood and anxiety disorders in patients with rheumatoid arthritis(WILEY-BLACKWELL PUBLISHING, INC, 2009) Uguz, Faruk; Akman, Cemal; Kucuksarac, Seher; Tufekci, OsmanThe purpose of the present study was to examine the current prevalence of mood and anxiety disorders, and factors related to mood and anxiety disorders in patients with rheumatoid arthritis (RA). The study sample included 83 consecutive patients with RA who were admitted to a rheumatology outpatient clinic. Diagnoses of psychiatric disorders were determined using the Structured Clinical Interview for DSM-IV (SCID-I). To assess physical disability and disease activity, the Health Assessment Questionnaire and the Disease Activity Score, respectively, were used. The prevalence of any mood or any anxiety disorder was 43.4%. The two most common psychiatric diagnoses were major depression (21.7%) and generalized anxiety disorder (16.9%). Mood and anxiety disorders were unrelated to sociodemographic features, disease-related factors, and medications for RA except anti-tumor necrosis factor-alpha (TNF-alpha). These disorders, however, were identified less frequently in patients with RA receiving anti-TNF-alpha drugs compared to patients who did not receive such medications. Patients with RA frequently have mood and anxiety disorders, and anti-TNF-alpha drugs may be useful for the mental status of these patients.Öğe Association of paraoxonase-1 activity and major depressive disorder in patients with metabolic syndrome(SPRINGER INDIA, 2015) Ari, Hatem; Kayrak, Mehmet; Gunduz, Mehmet; Kayhan, Fatih; Kaya, Zeynettin; Kiyici, Aysel; Uguz, FarukAssociations between metabolic syndrome (MS) and major depressive disorder (MDD) are well documented although the underlying biological mechanisms for this relationship are less studied. Paraoxonase (PON1) is a high-density lipoprotein (HDL)-associated enzyme, with demonstrated evidence of strong antioxidant activity. Oxidative stress has been implicated in the pathophysiology of MS and MDD. PON1 activity has been studied to some extent in patients with MS and less in MDD. The aim of this study was to compare serum PON1 activity in patients with MS and MDD, MS without MDD, and normal control groups in the context of the biological mechanism of the association between MS and MDD. In this case-control study, 67 patients with MS and 25 healthy controls from the hospital-university staff were recruited. All patients and healthy controls were assessed by a semi-structured psychiatric interview. Patients with MDD were diagnosed according to the DSM-IV criteria for MDD. Serum PON1 activity was determined with a spectrophotometric method, and the activity was compared between patients with MS and MDD, with MS but without MDD, and control groups. Serum PON1 activity levels were lower in patients with MS and MDD group compared to those in the patients with MS and without MDD group and control group (69.5+/-24.2, 84.3+/-34.6, and 97.1+/-40.8 U/ml, p=0.03, respectively). Post hoc analysis showed that PON1 activity was statically significantly lower in the MS with MDD group than in the control group (p=0.02). Impaired PON1 activity, in the context of enhanced oxidative stress, could be one of the possible underlying biological mechanisms of the MS-MDD association.Öğe Axis I and Axis II diagnoses in patients with chronic idiopathic urticaria(PERGAMON-ELSEVIER SCIENCE LTD, 2008) Uguz, Faruk; Engin, Burhan; Yimaz, ErtanObjective: This study presents the current prevalence of Axis I and Axis II psychiatric diagnoses and factors associated with the existence of Axis I psychiatric disorders in patients with chronic idiopathic urticaria (CIU). Method: The study sample was composed of 89 patients with CIU and 64 control subjects. Axis I and Axis II psychiatric disorders were ascertained by means of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition and the Structured Clinical Interview for DSM, Revised Third Edition Personality Disorders, respectively. Results: Of patients with CIU, 44 (49.4%) had at least one Axis I diagnosis, and 40 (44.9%) had at least one personality disorder. The most common Axis I disorder was obsessive-compulsive disorder (25.8%), and the most common Axis II disorder was obsessive-compulsive (30.3%) personality disorder in patients with CIU. Obsessive-compulsive disorder, major depression, obsessive-compulsive and avoidant personality disorders were more prevalent in patient group compared to control group. Obsessive-compulsive and avoidant personality disorders were related to the existence of Axis I disorders in patients with CIU. Conclusion: Psychiatric morbidity seems to be a frequent healthy problem in patients with CIU. (c) 2008 Elsevier Inc. All rights reserved.Öğe Biological correlates of major depression and generalized anxiety disorder in women with polycystic ovary syndrome(PERGAMON-ELSEVIER SCIENCE LTD, 2013) Annagur, Bilge Burcak; Tazegul, Aybike; Uguz, Faruk; Kerimoglu, Ozlem Secilmis; Tekinarslan, Emine; Celik, CetinObjective: We aimed to compare the levels of serum androgens in women with polycystic ovary syndrome (PCOS) who had a diagnosis of only major depressive disorder (MDD), only generalized anxiety disorder (GAD) or who had no psychiatric disorder, as determined by a structured clinical interview. Another objective of the study was to examine whether an association exists between these psychiatric diagnoses and insulin resistance or body mass index via a comparison among the study groups in terms of these parameters. Method: This study was performed between March 2011 and February 2012. A total of 73 patients were included in the study. The study sample consisted of three groups: PCOS patients with only major depressive disorder (n = 23), PCOS patients with only generalized anxiety disorder (n = 20), and PCOS patients without any diagnosed psychiatric disorders (not diagnosed - ND group, n = 30). Results: Significant difference was found among the three groups with regard to the serum levels of 17-OHP and DHEAS. When multiple comparisons were performed among the groups, 17-OHP levels were significantly higher in the MDD group than in the ND group. DHEAS levels were significantly higher in the MDD group and the GAD group than in the ND group. Conclusion: The present study suggests that MDD and GAD appear to be associated with higher DHEAS levels. (C) 2013 Elsevier Inc. All rights reserved.Öğe Birth Weight and Preterm Birth in Babies of Pregnant Women With Major Depression in Relation to Treatment With Antidepressants(LIPPINCOTT WILLIAMS & WILKINS, 2014) Sahingoz, Mine; Yuksel, Goksen; Karsidag, Cagatay; Uguz, Faruk; Sonmez, Erdem Onder; Annagur, Bilge Burcak; Annagur, AliObjective It is unclear whether antidepressant treatment has a preventive effect on negative neonatal outcomes due to major depression in pregnant women. The objective of the present study was to compare women with major depression treated with antidepressants, untreated women with major depression, and healthy women during pregnancy with respect to birth weight and preterm birth. Methods The study sample included a total of 23 women taking antidepressant medication, 36 women who were not taking antidepressant medication for major depression during pregnancy, and 30 healthy women. Major depression was diagnosed via the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Results The study groups were similar with respect to sociodemographic characteristics. Compared with infants of healthy control subjects, infants of untreated major depressed women had significantly lower birth weight and shorter gestational age at delivery. There is no significant difference between infants of major depressed women treated with antidepressants and infants of healthy subjects for these variables. Conclusions Our results suggest that antidepressants may have beneficial effects on the risk of low birth weight and preterm birth in the infants of depressed women.Öğe Clinical correlates of worsening in obsessive-compulsive symptoms during pregnancy(ELSEVIER SCIENCE INC, 2011) Uguz, Faruk; Kaya, Veli; Gezginc, Kazim; Kayhan, Fatih; Cicek, ErdincThis study examined clinical factors related to worsening of obsessive-compulsive disorder (OCD) in pregnant women. For comorbid diagnoses at the onset of pregnancy and frequency of several obsessive-compulsive symptoms, there was a significant difference between women whose OCD worsened during the pregnancy and those in whom the OCD did not worsen. Crown Copyright (C) 2011 Published by Elsevier Inc. All rights reserved.Öğe The Comparison of Depression, Anxiety and Quality of Life Levels Among Trimesters of Pregnancy(2010) Karataylı, Savaş; Gezginç, Kazım; Uguz, Faruk; Karataylı, Rengin; Çilli, Ali SavaşObjective: To compare the levels of depression, anxiety and quality of life among trimesters of pregnancy. Study Design: A total number of 200 patients;50 pregnant women from each trimester and 50 control group women who are not pregnant but with similar sociodemographic characteristics were included. To determine the levels depressive and anxiety symptoms and quality of life were performed the Beck Depression Inventory (BDI) the Beck Anxiety Inventory (BAI) and the World Health Organization Quality of Life Assessment Brief (WHOQOL-BREF), respectively. Results: While BDE and BAE points in pregnant were indifferent between trimesters; these points were found significantly higher compared with control group. There were significant differences for WHOQOL-BREF and the lowest quality of life was present at 3rd trimester. Conclusion: The levels of anxiety and depression were high, and quality of life was low in all trimesters, especially at 3rd trimester. Especially at advanced stages of pregnancy; the health care givers should evaluate pregnant women for depression and anxiety.Öğe Course of panic disorder during the early postpartum period: a prospective analysis(W B SAUNDERS CO-ELSEVIER INC, 2008) Guler, Ozkan; Koken, Gulengul N.; Emul, Murat; Ozbulut, Omer; Gecici, Omer; Uguz, Faruk; Gezginc, KazimPurpose: Most of the studies about course of panic disorder (PD) after childbirth have a retrospective nature. The aim of the current study was to examine prospectively the clinical course of 13 pregnant women with a diagnosis of PD across pregnancy and the early postpartum period. Method: The diagnosis of PD was determined by means of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I Disorders in the third trimester of pregnancy. Within the same period, the Panic and Agoraphobia Scale was used to determine the severity of PD. The last assessment with both instruments was performed at 6 weeks postnatally. Results: Of these 13 women, 6 (group 1) reported that PD developed during the 6th to the 28th week of their gestation, and the number of women who experienced PD symptoms before pregnancy (group 2) was 7. It was found that the severity of panic symptoms considerably decreased in the total sample, group 1, and group 2 from the basal levels to 6 weeks postnatally. Conclusion: Our study results suggest that pregnant women with PD may experience a marked improvement in PD symptoms in the early postpartum period. (c) 2008 Elsevier Inc. All rights reserved.Öğe Dissociative Symptoms Secondary to Piracetam: A Case Report(KURE ILETISIM GRUBU A S, 2013) Aydin, Adem; Ozdemir, Pinar Guzel; Selvi, Yavuz; Uguz, Faruk; Cetinkaya, NuralayPiracetam is a cyclic derivative of gamma-aminobutyric acid that is often used in neurology. Piracetam is an antithrombotic, neuroprotective agent which improves cognitive performance. Piracetam is indicated for vertigo in clinical practice. The etiology of dissociation is not precisely defined. In pharmacotherapy studies, depersonalization is the basic dissociative symptom. In this article, we have reported a case with the diagnosis of peripheral vertigo where piracetam was used as part of combination therapy. However dissociative symptoms like depersonalization and derealization occurred after piracetam use and these symptoms disappeared after discontinuation of piracetam.Öğe The effects of maternal major depression, generalized anxiety disorder, and panic disorder on birth weight and gestational age: A comparative study(PERGAMON-ELSEVIER SCIENCE LTD, 2013) Uguz, Faruk; Sahingoz, Mine; Sonmez, Erdem Onder; Karsidag, Cagatay; Yuksel, Goksen; Annagur, Bilge Burcak; Annagur, AliObjective: The present study comparatively examined the impact of maternal major depression, generalized anxiety disorder and panic disorder on gestational age and birth weight. Methods: A total of 90 women (24 subjects with major depression, 19 subjects with panic disorder, 22 subjects with generalized anxiety disorder, and 25 healthy subjects) in the perinatal period who were admitted to three hospitals were included in the study. Psychiatric diagnoses were determined by means of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. The birth weight and gestational age of the subjects in each groups were compared with one-way analysis of variance (ANOVA). Results: There were significant differences among the study groups for birth weight and gestational age (P < 0.001 for both variables). These parameters were significantly lower in the subjects with major depression (P = 0.021 and P = 0.015, respectively) and panic disorder (P < 0.001 for both variables) compared to healthy controls. Compared with major depression, panic disorder was associated more negatively with birth weight (P = 0.036). Conclusion: Major depression, and especially panic disorder, may negatively affect the gestational length and birth weight. (C) 2013 Elsevier Inc. All rights reserved.Öğe The impact of obsessive-compulsive disorder in pregnancy on quality of life(TAYLOR & FRANCIS LTD, 2008) Gezginc, Kazim; Uguz, Faruk; Karatayli, Savas; Zeytinci, Esra; Askin, Ruestem; Gueler, Oezkan; Sahin, FigenAim. To examine the effects of obsessive-compulsive disorder (OCD) on quality of life in pregnant women. Material and method. Twenty-five pregnant women diagnosed as OCD in two university outpatient clinics were included for the study. Twenty-five pregnant women with no mental disorders and the same sociodemographic properties were taken as the control group. The diagnosis of OCD was confirmed with the DSM-IV Axis-I Disorders Structured Clinic Interview Diagnosis/Clinic Version (SCID-I/CV). In order to measure the severity of OCD Yale-Brown Obsession and Compulsion Scale was performed. Quality of life was evaluated by WHO (World Health Organisation) Life Quality Scale - Short Form (WHOQOL-Brief). Results. The whole subgroup of points of WHOQOL-Brief was significantly lower in OCD patients compared to control group (in all subgroups P < 0.01). There was a negative correlation between the Y-BOCS obsession and compulsion subpoints and total points with the physical health (P < 0.05), psychological health (P < 0.001) and social relationship (P < 0.01) of WHOQOL-Brief. No significant association was found with enviromental areas. Besides, there was a negative correlation between the duration of OCD and WHOQOL-Brief psychological health subarea (P < 0.05). Conclusion. OCD negatively effects the quality of life in pregnant women and is correlated with the severity of the disorder.Öğe The impact of psychiatric disorders on quality of life in patients with rheumatoid arthritis(CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2009) Uguz, Faruk; Kucuksarac, Seher; Akman, Cemal; Tufekci, OsmanObjective: In recent years, the relationship between quality of life (QoL) and mental disorders in subjects with medical illnesses has been acquiring more importance. The present study was designed to examine the effects of psychiatric disorders on QoL in patients with rheumatoid arthritis (RA). Methods: The study was carried out among patients with RA who admitted to rheumatology outpatient clinic of department of physical medicine and rehabilitation of an university hospital. The study sample included 30 RA outpatients with axis I psychiatric disorder, 30 RA outpatients and 30 healthy subjects without any axis I psychiatric disorder. The psychiatric disorders were determined by means of the Structured Clinical Interview for DSM-IV. To determine the participants' QoL levels, we used the World Health Organization QoL Assessment-Brief (WHOQOL-BREF). Disease activity for RA was assessed with the Disease Activity Score. Results: Most of patients with RA were women, and they were mostly taking medications such as non-steroid anti-inflammatory drugs, corticosteroids, and metothrexate. Of RA patients with psychiatric disorders, 50% (15) had only depressive disorders, and 20% (6) had only anxiety disorders. The study groups had similar features with respect to age, sex, educational level, and marital status. There was no significant difference for treatments, disease duration and disease activity between RA patients with and without axis I psychiatric disorder. The QoL levels of all domains were lowest in RA patients with a psychiatric diagnosis. In addition, RA patients without psychiatric disorder had significantly lower scores of WHOQOL-BREF compared to healthy controls. Conclusion: The study results suggest that patients with RA have poorer QoL levels, and that psychiatric disorders appear to be a considerable factor affecting QoL of patients with RA. (Anatolian Journal of Psychiatry 2009; 10: 94-99)Öğe Longitudinal assessment of symptom and subtype categories in obsessive-compulsive disorder(WILEY-LISS, 2007) Besiroglu, Lutfullah; Uguz, Faruk; Ozbebit, Ozgur; Guler, Ozkan; Cilli, Ali Savas; Askin, RustemAlthough it has been postulated that symptom subtypes are potential predictors of treatment response, few data exist on the longitudinal course of symptom and subtype categories in obsessive-compulsive disorder (OCD). Putative subtypes of OCD have gradually gained more recognition, but as yet there is no generally accepted subtype discrimination. Subtypes, it has been suggested, could perhaps be discriminated based on autogenous versus reactive obsessions stemming from different cognitive processes. In this study, our aim was to assess whether symptom and subtype categories change over time. Using the Yale-Brown Obsessive Compulsive Symptom Checklist (Y-BOCS-SC), we assessed 109 patients who met DSM-IV criteria for OCD to establish baseline values, then reassessed 91 (83%) of the initial group after 36 +/- 8.2 months. Upon reassessment, we found significant changes from baseline within aggressive, contamination, religious, symmetry and miscellaneous obsessions and within checking, washing, repeating, counting and ordering compulsion categories. Sexual, hoarding, and somatic obsessions, and hoarding and miscellaneous compulsions, did not change significantly. In accordance with the relevant literature, we also assigned patients to one of three subtypes-autogenous, reactive, or mixed groups. Though some changes in subtype categories were found, no subtype shifts (e.g., autogenous to reactive or reactive to autogenous) were observed during the course of the study. Significantly more patients in the autogenous group did not meet OCD criteria at follow-up than did patients in the other groups. Our results suggest that the discrimination between these two types of obsession might be highly valid, because autogenous and reactive obsessions are quite different, both in the development and maintenance of their cognitive mechanisms, and in their outcome.Öğe One year follow-up of post-partum-onset depression: the role of depressive symptom severity and personality disorders(TAYLOR & FRANCIS LTD, 2009) Uguz, Faruk; Akman, Cemal; Sahingoz, Mine; Kaya, Nazmiye; Kucur, RahimObjective. Long-term follow-up and risk factors of persistent post-partum depression (PPD) are fairly unknown compared with its prevalence in the developing countries. In this study, we did a follow-up measure of PPD and examined the factors, which were associated with PPD 1-year post-partum. Method. Our sample comprised of 34 women. Depressive symptoms were assessed by the Edinburgh post-natal depression scale (EPDS) 6 weeks post-partum, and women with scores 12 on this scale was categorised as depressed. Personality disorders were determined at the same occasion by means of the Structured Clinical Interview for DSM-III-R personality disorders (SCID-II). One year post-partum EPDS was completed. Results. The rate of PPD 1-year post-partum was 32.4%, and it was unrelated to age at assessment, primiparity, number of children, employment status, economical status and educational level. Women depressed 1-year post-partum had significantly higher basal scores of EPDS and more often also a diagnosis of any axis II disorder; and specifically dependent and obsessive-compulsive personality disorders. In our sample, the predictors of 1-year post-partum PPD were having higher basal score of EPDS and the existence of a personality disorder. Conclusion. This study suggests that women with PPD, scoring high in the EPDS scale 6 weeks post-partum and having a personality disorder, run a higher risk for depression at 1-year follow-up.Öğe One year follow-up of postpartum-onset obsessive-compulsive disorder: A case series(PERGAMON-ELSEVIER SCIENCE LTD, 2008) Uguz, Faruk; Kaya, Nazmiye; Sahingoz, Mine; Cilli, Ali Savas; Akman, Cemal[Abstract not Available]Öğe Postpartum-onset major depression is associated with personality disorders(W B SAUNDERS CO-ELSEVIER INC, 2007) Akman, Cemal; Uguz, Faruk; Kaya, NazmlyeObjectives: The objective of the study was to investigate the incidence rate of postpartum-onset major depression (PPMD) and to examine associated sociodemographic characteristics, obstetric factors, and personality disorders. Method: The study data were obtained from 302 women who delivered at a child and maternity hospital. We interviewed the new mothers on the first day of their childbirth and at 6 weeks postpartum. Major depression and axis 11 diagnoses were determined by means of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition, Personality Disorders, respectively. Results: Nineteen (6.3%) women had new-onset major depression during 6 weeks postpartum. Postpartum-onset major depression was unrelated to age, educational level, employment status, planned or unplanned pregnancy, history of abortion and gestational complications, term of delivery, type of delivery, sex of the baby, and mother's breast-feeding. Frequency of primiparity and of avoidant, dependent, and obsessive-compulsive personality disorders was higher in women with PPMD than that in women without PPMD. As a result of logistic regression analysis, the independent predictor of PPMD was the presence of avoidant, dependent, and obsessive-compulsive personality disorders. Conclusion: Our results suggest that childbearing women with avoidant, dependent, and obsessive-compulsive personality disorders have increased risk of new-onset major depression during the postpartum period. (c) 2007 Elsevier Inc. All rights reserved.Öğe Postpartum-onset obsessive-compulsive disorder: Incidence, clinical features, and related factors(PHYSICIANS POSTGRADUATE PRESS, 2007) Uguz, Faruk; Akman, Cemal; Kaya, Nazmiye; Cilli, Ali SavasObjective: The aims of this study were to investigate the incidence rate and symptomatology of postpartum-onset obsessive-compulsive disorder (PPOCD), to investigate the factors associated with PPOCD, and to compare clinical characteristics of obsessive-compulsive disorder (OCD) with and without postpartum onset. Method: The study data were collected from 302 women who delivered at a child and maternity hospital in Turkey from August 2005 to November 2005 and a control group of 33 women who were admitted to the psychiatric outpatient clinic of a university hospital during the same time period and who met DSM-IV criteria for OCD. The 2 clinical interviews with women who delivered were performed face-to-face on the first day after childbirth and at 6 weeks postnatally. OCD and comorbid Axis II disorders were diagnosed by means of the Structured Clinical Interview for DSM-IV and the Structured Clinical Interview for DSM-III-R Personality Disorders, respectively. Obsessive-compulsive symptomatology was assessed with the Yale-Brown Obsessive Compulsive Scale. Results: The incidence of PPOCD was 4% at 6 weeks postnatally. The most common obsessions in women with PPOCD were contamination (75%), aggressive (33.3%), and symmetry/exactness (33.3%), and the most common compulsions were cleaning/washing (66.7%) and checking (58.3%). The patients with PPOCD had significantly more frequent aggressive obsessions (p=.039) and less severe obsessive-compulsive symptoms (p=.013) than the OCD patients without postpartum onset. The predictors of PPOCD were avoidant (p=.000) and obsessive-compulsive (p=.004) personality disorders. Conclusions: This study suggests that the puerperium is a risk period in terms of new-onset OCD and that avoidant and obsessive-compulsive personality disorders predict PPOCD.Öğe Pregnancy-Onset Panic Disorder: Incidence, Comorbidity and Associated Factors(AVES, 2015) Guler, Ozkan; Kaya, Veli; Gezginc, Kazim; Kayhan, Fatih; Cicek, Erdin; Sonmez, Onder; Uguz, FarukIntroduction: The present study aimed to investigate the incidence rate of pregnancy-onset panic disorder (POPD) among Turkish pregnant women using a diagnostic interview. Additionally, we examined whether the independent socio-demographic or clinical risk factors were associated with the risk of panic disorder in these women. Methods: The study sample comprised 1475 consecutive pregnant women who presented to the obstetric outpatient clinics of two research centers. The rate of POPD in these participants was 1.3% (Group 1, n= 20). The 20 women with POPD were compared with 250 pregnant women without pregnancy-onset depression or anxiety (Group 2; controls). Panic disorder and other anxiety or mood disorders were determined by means of the Structured Clinical Interview for DSM-IV. Comorbid Axis II disorders were diagnosed with the Structured Clinical Interview for DSM-III-R Personality Disorders. Results: The incidence rate of panic disorder was 1.3% (n= 20). In group 1, 55% (n= 11) of the women with POPD had an additional mood or anxiety disorder. In addition, the prevalence rate of any cluster C personality disorder, including avoidant, passive-aggressive and obsessivecompulsive personality disorders, were significantly greater in the group 1 women with POPD than the control pregnant women without a panic disorder (group 2). Conclusion: The women with POPD were more likely than the controls to have a cluster C Axis II disorder and a history of a pre-existing anxiety or mood disorder.Öğe Prevalence and Related Factors of Mood and Anxiety Disorders in a Clinical Sample of Postmenopausal Women(WILEY-BLACKWELL, 2011) Sahingoz, Mine; Uguz, Faruk; Gezginc, KazimPURPOSE: The purpose of the study was to investigate the prevalence and related factors of mood and anxiety disorders in postmenopausal women attending a gynecological outpatient clinic. METHODS: The study sample included 269 postmenopausal women. The Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, 4th edition was performed to determine the disorders. RESULTS: Ninety-two (34.2%) women had at least one mood or anxiety disorder. The most common specific disorder was generalized anxiety disorder (15.6%). The existence of any mood or anxiety disorder was associated with poorer economic level. CONCLUSIONS: Mood and anxiety disorders were frequently observed in postmenopausal women who were admitted to a gynecology outpatient clinic.