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Van der Knaap Hastalığı: Manyetik Rezonans Görüntüleme Bulguları: Olgu Sunumu
(Selçuk Üniversitesi, 2017 Haziran) Kıvrak, Ali Sami; Nayman, Alaaddin; Paksoy, Yahya; Aydın, Kürşat
Van der Knaap hastalığı, megalensefalik lökoensefalopati ve subkortikal kistlerle karakterize nadir bir antitedir. Bu yazıda Van der Knaap hastalığı’nın radyolojik ve klinik tanı kriterlerine sahip üç pediatrik olgunun beyin manyetik rezonans görüntüleme (MRG) ve manyetik rezonans spektroskopi (MRS) bulguları sunulmuştur.
Tip B Kesintili Arkus Aorta: Olgu Sunumu
(Selçuk Üniversitesi, 2019 Ocak) Fazlıoğulları, Zeliha; Doğan, Nadire Ünver; Sevindik, Betül; Seher, Nusret; Karabulut, Ahmet Kağan
Kesintili arkus aorta nadir rastlanan, fatal seyirli konjenital kardiyak bir anomali olup, aorta ascendens ile aorta descendens arasındaki bir segmentte atrezinin olması şeklinde tanımlanır ve %98 oranında diğer kardiovasküler anomalilerle birlikte bulunur. Üç tipi mevcuttur. Tip A’ da kesinti, a. subclavia sinistra’nın distalindedir. Tip B’de, a. carotis communis sinistra ile a. subclavia sinistra, tip C’de, a. carotis communis sinistra ile a. carotis communis dextra arasındadır. Selçuk Üniversitesi pediatrik kardiyoloji kliniğine başvuran postnatal 5. gününde bir erkek bebeğin çekilen ekokardiyografisinde; truncus brachiocephalicus’un distalinden itibaren tip B kesintili arkus aorta, ventriküler septal defekt, biküspit aorta, patent ductus arteriosus, atrial septal defekt, annulus aorticus hipoplazisi tespit edildi. Bilgisayarlı tomografi anjiyografisinde ise, a. carotis communis sinistra ile a. subclavia sinistra arasında bağlantı olmadığı görüldü. Bu vakada, arcus aorta anomalisi ve eşlik eden diğer kardiovasküler anomalilerin erken tanı ve tedavisinde radyolojik görüntüleme yöntemlerinin önemi vurgulanmaktadır.
Trakeal Bronkus: Bir Olgu Sunumu
(Selçuk Üniversitesi, 2019 Mart) Solmaz, Ekrem; Cebeci, Hakan; Tatar, Mehmet Cengiz; Fazlıoğulları, Zeliha
Trakeal bronkus, trakeadan kaynaklanan sağ bronchus lobaris superior olup, ilk olarak 1785’te tanımlanmıştır. Genelde karinanın sağ üst tarafında, sağ akciğerin üst lobunun segmentum apicale’sini havalandıran nadir görülen konjenital bir anomalidir ve üç tipi vardır. Bir yıldır öksürük ve nefes darlığı şikayeti olan 41 yaşındaki erkek hastanın çekilen kontrastlı aksiyal ve koronal reformat toraks bilgisayarlı tomografisinin incelenmesi sonucunda sağ akciğerindeki bronchus lobaris superior’unun karina üstünden ayrıldığı görülmüştür. Tekrarlayan akciğer enfeksiyonu olan hastalarda ve özellikle Down sendromu olmak üzere konjenital kalp hastalıkları, aspleni sendromu ve kosta anomalileri gibi ek anomalisi olan vakalarda olası trakeobronşial anomaliler akılda tutulmalıdır. Bu hastalara uygulanan yanlış endotrakeal entübasyonun, atelektazi ve pnömotoraks gibi komplikasyonlara neden olabileceği düşünülmelidir. Bunun yanı sıra anestezi öncesi bilgisayarlı tomografi ile anatomik yapının değerlendirilmesi varyasyonların tanımlanması açısından önemlidir.
Over Kan Akımının Değerlendirilmesinde Transabdominal Superb Mikrovasküler Görüntüleme ve Konvansiyonel Doppler Görüntüleme Tekniklerinin Karşılaştırılması
(Selçuk Üniversitesi, 2019 Mart) Arslan, Serdar; Durmaz, Mehmet Sedat
Amaç: Bu çalışmada, transabdominal Superbmikrovasküler görüntüleme (SMG), color Doppler (CD) ve power Doppler (PD) görüntüleme yöntemlerinin sağlıklı gönüllülerde intraovarianvaskülariteyi saptamada etkinliği karşılaştırılmıştır. Gereç ve Yöntem: Çalışmaya yaşları 0 – 34 arasında olan 81 sağlıklı gönüllü (n = 162over) dahil edildi. Tüm katılımcılar transabdominal B-modultrasonografi, CD, PD ve SMG ile ayrı ayrı incelendi. Over hacimleri B-mod ultrasonografi ile ölçüldü, ardından CD, PD, SMG (cSMG) ve monokrom SMG (mSMG) yoluyla over kan akımları değerlendiriledi. Bulgular: SMG, over dokusunda düşük hızlı kan akım sinyallerini saptamada CD ve PD'den daha etkiliydi (p> 0.001). CD, PD, cSMG ve mSMG'deki ortalama ovaryanvaskülerite skoru sırasıyla, 0,5 ± 1, 1,8 ± 1,5, 3,3 ± 1,3 ve 4,3 ± 0,9 idi.Over hacimleri ve sağlıklı gönüllülerin yaş ortalaması azaldıkça, mSMG ve cSMG yöntemleri konvansiyonel Doppler tekniklerine göre overvaskülaritesini daha iyi gösterdi. Sonuç: Transabdominal SMG, overvasküleritesini diğer konvansiyonel Doppler tekniklerine kıyasla daha ayrıntılı göstermektedir. SMG, özellikle çocuk hastalarda overvasküleritesinin değerlendirilmesi için inceleme protokolünün bir parçası olmalıdır.
MR İle Saptanan Uterus Didelphys Bicollis Olgusu
(Selçuk Üniversitesi, 2019 Aralık) Özcan, Ayşe Gamze; Doğan, Nadire Ünver; Baytok, Ahmet; Fazlıoğulları, Zeliha
Uterus'un nadir görülen varyasyonlarından olan uterus didelphys, mu?llerian fu?zyonun gerc?ekles?memesi sonucu olus?maktadır. İlk olarak 1925 yılında Wilson tarafından rapor edilmiştir. Bu varyasyonda, iki ayrı cavitas uteri ve iki cervix uteri longitudinal vajinal septum ile birleşmektedir. Mu?llerian kanal anomalileri literatürde %0,1- 3,5 sıklıkta bildirilmektedir. Uterus didelphys ise bu anomalilerin % 5’ini oluşturmaktadır. Mu?llerian kanal malformasyonlarına %20 oranında renal anomaliler es?lik etmektedir. Selçuk Üniversitesi Tıp Fakültesi’ne dismenore şikayeti ile başvuran 21 yaşındaki kadın hastanın dinamik kontrastlı pelvik MR ve difüzyon MR görüntüleri incelemesinde uterus didelphys bicollis varyasyonu belirlendi. Genellikle uterus didelphys olguları asemptomatik olup bazen dismenore, tekrarlayan abortus veya infertilite gibi şikayetlere sebep olabilirler. Uterus anomalilerin teşhisinde MR görüntüleri çok değerlidir. Uterus varyasyonları olan kişilerde muayene ve görüntüleme teknikleriyle özellikle gebelik öncesinde tanı konulması komplikasyonların önlenmesi açısından oldukça önemlidir.
Pektus Ekskavatum Hastalarında Minimal İnvaziv Cerrahinin Akciğer Hacimlerine Olan Etkisinin Kantitatif Bt Volumetri ile Değerlendirilmesi
(Selçuk Üniversitesi, 2020 Eylül) Cebeci, Hakan; Özlü, Mustafa Yasir; Kılınçer, Abidin; Öztürk, Mehmet; Yıldıran, Hüseyin; Sunam, Güven Sadi; Öncel, Murat
Amaç: Pektus ekskavatum çocuklarda en sık görülen doğumsal göğüs duvarı anomalisidir. Bu çalışmada minimal invaziv cerrahi yapılan pektus ekskavatum hastalarında akciğer hacimlerinin kantitatif BT volumetri ile araştırılması amaçlanmıştır. Gereç ve Yöntem: Etik kurul onayı alındıktan sonra, Ocak 2012 ile Şubat 2018 tarihleri arasında minimal invaziv pektus ekskavatum cerrahisi yapılmış hastalar retrospektif olarak tarandı. Preoperatif ve postoperatif BT incelemesi bulunan hastalar çalışmaya dahil edildi. BT görüntüleri iş istasyonuna aktarılarak akciğer hacimleri ve Haller indeksleri hesaplandı. Bulgular: Çalışmaya dahil edilen hastaların (11 erkek, 1 kadın) ortalama yaşları 16,3 ± 3,7 bulundu. Postoperatif akciğer hacimlerinde anlamlı düzeyde artış saptandı. Total akciğer hacimlerindeki ortalama artış 695 ± 691 ml idi. Preoperatif Haller indeksi ortalaması 3,1’den 2,7’ye düştü ve arada anlamlı fark vardı (p=0,002). Sonuç: Kantitatif BT volumetri, minimal invaziv cerrahi yapılan pektus ekskavatum hastalarında akciğer hacmindeki değişiklikleri değerlendirilmesinde yararlı bilgiler sağlamaktadır.
Tüm barsaklar sana emanet: Truncus coeliacamesenterica
(Selçuk Üniversitesi, 2021) Pirinç, Büşra; Nayman, Alaaddin; Fazlıoğulları, Zeliha; Karabulut, Ahmet Kağan
Truncus coeliacus ve a. mesenterica superior, gastrointestinal sistemin önemli bir bölümünü besleyen iki damardır. Bu iki damarın ortak bir kök ile aorta abdominalis’ten ayrılması nadir görülen ve oldukça önemli bir varyasyondur. 63 yaşındaki erkek hastanın 256 kesitli multidedektör bilgisayarlı tomografi anjiografi görüntüleri incelendi. Yapılan değerlendirmede truncus coeliacus ve a. mesenterica superior’un ortak bir kök halinde 1. lumbal vertebra’nın alt hizasında aorta abdominalis’in ön yüzünden ayrıldıkları tespit edildi. Bunun yanı sıra; a. gastrica sinistra’nın a. hepatica propria’dan orijin aldığı gözlendi. Truncus coeliacus’un varyasyonları karaciğer nakilleri, safra kesesi ve gastrik bölge cerrahisinin yanı sıra girişimsel radyolojik prosüdürlerde de oldukça önemlidir.
Quantitative analysis of thyroid gland blood supply in children and adolescents
(Selçuk Üniversitesi, 2022) Uysal, Emine; Öztürk, Mehmet; Bayramoğlu, Zuhal; Cebeci, Hakan
Aim: This study aims to determine the reference vascularization index (VI) values for the thyroid gland in healthy children and adolescents using Super microvascular imaging (SMI). It was also investigated that the correlation between thyroid vascularity and thyroid lobe volumes, age, sex, weight, height, and body mass index (BMI). Materials and Methods: One hundred and twenty-four children and adolescents without a thyroid gland and systemic disease, and medical history affecting the thyroid gland were included in the study. Participants with abnormal thyroid function tests were excluded from the study. Age, gender, height, and weight were recorded before ultrasonography and SMI examinations. After the grayscale ultrasonography, VI values for each participant were obtained using SMI. The association between the VI and thyroid lobe volumes, age, sex, weight, height, and BMI values were analyzed. Results: Median values of the age, height, weight, and BMI of 124 participants were 10 (6-12) years, 130 (120-152) cm, 30.5 (21-47) kg, 17.55 (15.37-21.14) kg/m2, respectively. Median (IQR) values of the left and right thyroid lobe volumes were 1.4 (0.9-2.07) mL and 1.9 (1.2-3.07) mL, respectively, and the mean VI value was 5.31±1.84%. There was no significant association of VI values with the thyroid lobe volume. Also, there was no relation between the mean VI values and the auxological parameters. Conclusion: This study defines the VI values of thyroid glands in healthy adolescents and children. It also demonstrated no correlation between VI values of the thyroid gland and thyroid lobe volume, sex, age, weight, height, and BMI
Quantitative analysis of thyroid gland blood supply in children and adolescents
(Selçuk Üniversitesi, 2022) Bayramoğlu, Zuhal; Uysal, Emine; Öztürk, Mehmet; Cebeci, Hakan
Aim: This study aims to determine the reference vascularization index (VI) values for the thyroid gland in healthy children and adolescents using Super microvascular imaging (SMI). It was also investigated that the correlation between thyroid vascularity and thyroid lobe volumes, age, sex, weight, height, and body mass index (BMI). Materials and Methods: One hundred and twenty-four children and adolescents without a thyroid gland and systemic disease, and medical history affecting the thyroid gland were included in the study. Participants with abnormal thyroid function tests were excluded from the study. Age, gender, height, and weight were recorded before ultrasonography and SMI examinations. After the grayscale ultrasonography, VI values for each participant were obtained using SMI. The association between the VI and thyroid lobe volumes, age, sex, weight, height, and BMI values were analyzed. Results: Median values of the age, height, weight, and BMI of 124 participants were 10 (6-12) years, 130 (120-152) cm, 30.5 (21-47) kg, 17.55 (15.37-21.14) kg/m2, respectively. Median (IQR) values of the left and right thyroid lobe volumes were 1.4 (0.9-2.07) mL and 1.9 (1.2-3.07) mL, respectively, and the mean VI value was 5.31±1.84%. There was no significant association of VI values with the thyroid lobe volume. Also, there was no relation between the mean VI values and the auxological parameters. Conclusion: This study defines the VI values of thyroid glands in healthy adolescents and children. It also demonstrated no correlation between VI values of the thyroid gland and thyroid lobe volume, sex, age, weight, height, and BMI.
Morphometric Analysis of Orbit in Turkish Population: a MDCT Study
(Selçuk Üniversitesi, 2022) Pirinc, Busra; Fazliogullari, Zeliha; Koplay, Mustafa; Dogan, Nadire Unver; Karabulut, Ahmet Kagan
Objective: The orbit is an important cavity containing vision-related formations and important neurovascular structures, and adjacent to various regions. This study aimed to evaluation, by multidedector computed tomography (MDCT) images, the morphometry of orbit by examining its changes according to gender and body side, and developments according to age, in Turkish population. Materials and Methods: A total of 200 individuals’s (94 females,106 males;400 sides) MDCT images were evaluated. Images were examined according to the gender, body side, and the anatomical structures development. Results: The height, width and depth of the orbit were determined as 36.04±2.97 mm, 32.33±2.59 mm, 38.35±3.32 mm on the right side, 35.79±3.18 mm, 32.29±2.67 mm, 38.13±3.21 mm on the left side, respectively, in healthy subjects. The height and width of the orbit were found to be statistically significantly larger on both sides in men than in women (p?0.05). Conclusion: Comprehensive information about the orbit and associated apertures is quite important for clinicians working in this area, damage to these structures can cause serious complications. In addition, determining the morphometry of the orbit can be used as an important parameter for determining gender, age and race in forensic medicine.
Sexual dimorphism in the sheep corpus callosum using 3 tesla MRI
(Selçuk Üniversitesi Veterinerlik Fakültesi, 2021)
Amaç: Bu çalışmada formaldehit ile tespit edilmiş koyun beyninden 3T Manyetik Rezonans Görüntüleme (MRG) ile elde edilen yüksek çözünürlükteki görüntüler kullanılarak, corpus callosum’un cinsiyet açısından morfolojik ve morfometrik farklılıklarını ortaya koymak amaçlandı. Gereç ve Yöntem: Çalışmada formaldehit ile tespit edilmiş erişkin, sağlıklı ve herhangi bir anomalisi bulunmayan 9 adet dişi ve 9 adet erkek olmak üzere toplam 18 adet Akkaraman koyun beyni kullanıldı. Koyun beynindeki morfometrik ölçümler 3T MRG’den elde edilen T2 ağırlıklı görüntülerde gerçekleştirildi. İlk önce MIMICS programında corpus callosum’un kesit yüzey alanı hesaplandı. Morfometrik ölçümlerden önce MRcronGL programında DICOM formatındaki görüntüler NIfTI formatına dönüştürüldü. Daha sonra ITK-SNAP programında standart şablon kullanılarak görüntülerin normalizasyonu yapıldı. Normalizasyonu gerçekleştirilen görüntüler ITK-SNAP programında açılarak genu corporis callosi, truncus corporis callosi ve splenium corporis callosi’de morfometrik ölçümler gerçekleştirildi. Bulgular: Koyunlarda truncus corporis callosi’nin venticulus lateralis’in tavanını oluşturduğu alt yüzeyinin köpek ve kediye göre daha içbükey; insan, at ve tavşana göre ise daha düz olduğu tespit edildi. Corpus callosum uzunluğu, corpus callosum yüzey alanı, genu corporis callosi genişliği, truncus corporis callosi genişliği ve splenium corporis callosi genişliği’nde cinsiyet açısından fark tespit edilmedi. Corpus callosum yüzey alanı ile beyin ağırlığı ve hacmi arasındaki oranda benzer şekilde cinsiyet açısından fark gözlenmedi. Ancak yüzey alanı ile hacim arasındaki oranın insanlar ve diğer memelilerde yapılan araştırmalarda bu parametrede sıklıkla karşılaşılan farka çok yakın olduğu gözlendi. Öneri: Bu çalışmada sağlıklı koyun beyinlerinden elde edilen bulguların sinirbilimi çalışmalarında koyunlarda oluşturulan nörodejeneratif hastalık modellerinde ve deneysel çalışmalarda kullanılabileceği düşünülmektedir
Shear wave elastography evaluation of testes in patients with varicocele
(Lippincott Williams and Wilkins, 2020) Erdoğan, Hasan; Durmaz, Mehmet Sedat; Arslan, Serdar; Gokgoz Durmaz, Funda; Cebeci, Hakan; Ergun, Osman; Soğukpınar Karaağaç, Seda
We aimed to determine histological damage in patients with varicocele by comparing the elasticity of their affected testes with that of their normal contralateral testes as well as normal testes of control subjects without varicocele using shear wave elastography (SWE). In total, 48 patients with varicocele (96 testes) and 52 control subjects (104 testes) were included in this study. Shear wave elastography values were measured in the longitudinal plane using an oval region of interest that covered as much of the testicular contours as possible. Fifty testes with varicocele were classified as group A, 46 normal contralateral testes of the same patients as group B, and 104 normal testes of control subjects as group C. The normal group C testes were randomly chosen from patients who had applied for ultrasonography for any reason and agreed to participate in the study. The testicular volume and SWE values were compared between these 3 groups. The average age of the patients was 28.45 years, and no significant difference in age was found between the 3 groups (P = 0.665). A significant difference in the testicular volume was found between groups A and C (P = 0.014). The SWE values were significantly higher in group A than in groups B and C (P < 0.001). No significant correlation was observed between the testicular volume and SWE values in any of the groups. Our results showed that SWE can be used as an effective technique to assess testicular stiffness in patients with varicocele to predict interstitial fibrosis and the severity of histological damage.
Normative values of thymus in healthy children; stiffness by shear wave elastography
(AVES, 2020) Bayramoğlu, Zuhal.; Öztürk, Mehmet.; Çalışkan, Emine.; Ayyıldız, Hakan.; Adaletli, İbrahim.
PURPOSE Thymus grows after birth, reaches maximal size after the first few years and involutes by puberty. Because of the postnatal developmental and involutional duration, we aimed to investigate normal stiffness values of mediastinal thymus by shear wave elastography (SWE) in different age groups of children and discuss imaging findings of thymus. METHODS We prospectively examined 146 children (90 girls, 56 boys) who underwent a thyroid or neck ultrasound examination. All subjects underwent ultrasound and SWE evaluation of mediastinal thymus by parasternal and suprasternal approach. We grouped the subjects based on age as 0 to 2 months, >2 to 6 months, >6 months to 2 years, >2 to 5 years, >5 to 8 years, and greater than 8 years old. We investigated differences of mean shear wave elasticity (kPa) and shear wave velocity (m/s) values among age groups and the association of SWE values with age, body mass index (BMI), height, and weight of the patients. RESULTS Median and range of age, height, weight, and BMI were 24 months (2-84 months), 85 cm (55-120 cm), 12 kg (4.55-22 kg), 15.37 kg/m(2) (13.92-17.51 kg/m(2)), 11 cc (2.64-23.15 cc), respectively. Mean shear wave elasticity of thymus of all participants was 6.76 +/- 1.04 kPa. Differences of mean elasticity values among the age and gender groups were not statistically significant. Thymus elasticity and velocity values showed highly significant negative correlations with age (r=-0.3), height (r=-0.26), weight (r=-0.3) (P < 0.001). CONCLUSION Quantitative evaluation of the thymus by SWE provides normative stiffness values based on age and gender groups. The thymus elasticity decreases with increased age, height, and weight.
Evaluating nail thickness and stiffness with shear-wave elastography in nail psoriasis: A preliminary study
(WILEY, 2020) Islamoğlu, Zeynep Gizem Kaya.; Uysal, Emine.; Demirbaş, Abdullah.; Islamoğlu, Necat.
Introduction Psoriasis is a chronic, relapsing skin disease affecting millions of people worldwide. Nail changes have been reported to occur in up to 40% of patients with mild psoriasis and 50%-70% with severe disease. Shear-wave elastography (SWE) is a new non-invasive ultrasonic technique that evaluates thickness and stiffness of tissues. Aims To evaluate nail plate thickness and stiffness of patients with psoriasis and determine whether there are differences among psoriatic patients with and without nail involvement, and to investigate the feasibility of using SWE in assessing this disease. Materials and Methods Nail plate thickness and stiffness were investigated in 54 patients with psoriasis and 58 healthy controls. SWE was performed with an Aplio 500 ultrasound system. Results Increased nail plate thickness was observed more often in the affected nails of psoriatic patients compared to non-affected nails of patients and controls. Stiffness was similar in both groups. Conclusions Our study is the first report to evaluate the SWE scores in nail psoriasis. While it may not provide reliable information for diagnosis, it can be used for follow-up treatment.
Bone mineral density in emphysema and chronic bronchitis phenotypes in hospitalized male chronic obstructive pulmonary disease patients
(WILEY, 2020) Yormaz, Burcu; Cebeci, Hakan; Yılmaz, Farise; Süerdem, Mecit
Introduction Risk of osteoporosis known to increase in chronic obstructive pulmonary disease (COPD), but is usually overlooked, especially in male patients. Objectives The present study compares the bone mineral density (BMD) measurements of male COPD patients with emphysema and the chronic bronchitis phenotype, and evaluates the association between density of emphysema and osteoporosis. Methods Ninety-four patients with COPD, and with emphysema and the chronic bronchitis phenotype, were included in the prospective study. A high-resolution computed tomography (HRCT) was used for the diagnosis of emphysema, and a dual X-ray absorptiometry was used to measure the BMD of the lumbar vertebrae and neck of the femur. Results Emphysema phenotype 45.75% and chronic bronchitis phenotype 54.25%, based on their clinical findings and a quantitative volumetric analysis by HRCT. Osteoporosis was found 60.47% and 17.65% of patients with emphysema and bronchitis, while osteopenia was detected 27.91% and 41.18% of patients with emphysema and bronchitis, respectively. A negative correlation was found between HRCT emphysema density and the bone densitometer t-score in patients with osteoporosis. Among the patients with osteoporosis, a positive correlation was found between Body Mass Index (BMI) and the bone densitometer t-score. Only BMI and emphysema score were found to be independent risk factors for a low BMD. One unit drop in BMI increased the risk of osteoporosis by 28% (OR = 1.28, 95% CI 1.14-1.45) (P < 0.001). One unit increase in emphysema score increased the risk of osteoporosis by 6% (OR = 1.06, 95% CI 1.03-1.09) (P < 0.001). Conclusion Especially male patients with emphysema, high dyspnea score, low BMI and frequent exacerbations should be evaluated for osteoporosis.
Can shear wave ultrasound elastography be a useful tool for determining the tumor extent of basal cell carcinomas pre-operatively? A preliminary study
(WILEY, 2020) Unal, Mehmet.; İslamoğlu, Zeynep Gizem Kaya.; Öztürk, Mehmet.; Uysal, Emine.; İslamoğlu, Necat.
[Abstract not Available]
Adrenal tumor characterization on magnetic resonance images
(WILEY, 2020) Barstugan, Mucahid.; Ceylan, Rahime.; Asoglu, Semih.; Cebeci, Hakan.; Koplay, Mustafa.
Adrenal tumors occur on adrenal glands and are generally detected on abdominal area scans. Adrenal tumors, which are incidentally detected, release vital hormones. These types of tumors that can be malignant affect body metabolism. Both of benign and malign adrenal tumors can have a similar size, intensity, and shape, this situation may lead to wrong decision during diagnosis and characterization of tumors. Thus, biopsy is done to confirm diagnosis of tumor types. In this study, adrenal tumor characterization is handled by using magnetic resonance images. In this way, it is wanted that patient can be disentangled from one or more imaging modalities (some of them can includes X-ray) and biopsy. An adrenal tumor image set, which includes five types of adrenal tumors and has 112 benign tumors and 10 malign tumors, was used in this study. Two data sets were created from the adrenal tumor image set by manually/semiautomatically segmented adrenal tumors and feature sets of these data sets are constituted by different methods. Two-dimensional gray-level co-occurrence matrix (2D-GLCM), gray-level run-length matrix (GLRLM), and two-dimensional discrete wavelet transform (2D-DWT) methods were analyzed to reveal the most effective features on adrenal tumor characterization. Feature sets were classified in two ways: benign/malign (binary classification) and type characterization (multiclass classification). Support vector machine and artificial neural network classified feature sets. The best performance on benign/malign classification was obtained by the 2D-GLCM feature set. The best results were assessed with sensitivity, specificity, accuracy, precision, and F-score metrics and they were 99.17%, 90%, 98.4%, 99.17%, and 99.13%, respectively. The highest classification performance on type characterization was obtained by the 2D-DWT feature set as 59.62%, 96.17%, 93.19%, 54.69%, and 54.94% for sensitivity, specificity, accuracy, precision, and F-score metrics, respectively.
Neuro-Behçet disease presented with pachymeningitis in a child [Enfermedad de neuro-Behçet con paquimeningitis en una niña]
(Sociedad Argentina de Pediatria, 2019) Alkan, Gülsüm; Kartal, Ayşe; Emiroğlu, Melike; Paksoy, Yahya
Behçet’s disease (BD) is a rare systemic vasculitis disorder of unknown etiology characterized by recurrent oral and genital apthae and uveitis. It involves the central or peripheral nervous system; occurs rarely during childhood. Isolated acute aseptic meningitis is extremely uncommon. We report here a case of Neuro-Behçet disease (NBD) diagnosed in a 14-year-old girl. The patient presented acute headache, diplopia, papilla edema, and meningeal irritation. She had a history of recurrent oral ulcers. Brain magnetic resonance imaging revealed pachymeningitis. Pleocytosis and pressure increase were the cerebrospinal fluid findings. Although medical therapy, her complaints were not resolved. Uveitis was not detected, pathergy test was negative. HLA-B51 allele was positive. The findings were considered to unusual NBD. The patient improved dramatically after steroid therapy. BD should be considered in differential diagnosis of meningitis unless an infectious agent is demonstrated. To our knowledge, a case of pachymeningitis with NBD, was not described in children.
Unilateral hypertrophy of the C5 vertebra spinous process in an adolescent
(CUKUROVA UNIV, FAC MEDICINE, 2019) Başar, Ibrahim.; Öztürk, Mehmet.; Sağlık, Semih.
[Abstract not Available]
Two-dimensional shear wave elastography in the assessment of salivary gland ınvolvement in primary sjogren's syndrome
(WILEY, 2019) Arslan, Serdar.; Durmaz, Mehmet Sedat.; Erdogan, Hasan.; Esmen, Serpil Ergulu.; Turgut, Bekir.; Iyisoy, Mehmet Sinan.
Objectives The aim of this study was to investigate the diagnostic performance of two-dimensional (2D) shear wave elastography (SWE) in the assessment of salivary gland involvement in primary Sjogren's syndrome (pSS). Methods Fifty-three patients with pSS and 30 healthy volunteers were included. The echogenicity of all submandibular and parotid glands was evaluated with B-mode ultrasound, and their elasticity was assessed with 2D SWE. The mean and standard deviation of the shear wave speed and elasticity modes on 2D SWE were calculated. Results The mean shear wave speed and elasticity mode values for the submandibular and parotid glands were significantly higher in the patients with pSS (P < .05). The mean elasticity of the shear wave speed mode was best able to differentiate the parotid glands of patients with pSS from those of healthy volunteers at a cutoff value of 2.48 m/s, whereas the mean elasticity of the elasticity mode was best able to differentiate the submandibular glands of patients with pSS from those of healthy volunteers at a cutoff value of 21 kPa. Conclusions Two-dimensional SWE is an effective technique for assessment of the parenchyma of the salivary glands in patients with pSS and predicts interstitial fibrosis and the severity of histologic damage.

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